Results 91 to 100 of about 345,519 (275)
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
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Subharmonic solutions for nonlinear second order equations in presence of lower and upper solutions
Discrete and Continuous Dynamical Systems, 2013 We study the problem of existence and multiplicity of subharmonic solutions for a second order nonlinear ODE in presence of lower and upper solutions. We show how such additional information can be used to obtain more precise multiplicity results.
BOSCAGGIN, Alberto, ZANOLIN F.
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Molecular Oncology, EarlyView.Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
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Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy
Molecular Oncology, EarlyView.We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen +19 more
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Upper and lower bounds of solutions for fractional integral equations [PDF]
Surveys in Mathematics and its Applications, 2007 n this paper we consider the integral equation of fractional order in sense of Riemann-Liouville operator um(t) = a(t) Iα [b(t)u(t)]+f(t) with m ≥ 1, t ∈ [0, T], T < ∞ and 0< α
Rabha W. Ibrahim, Shaher Momani
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Upper and lower solution method for Hilfer fractional evolution equations with nonlocal conditions
Boundary Value Problems, 2019 This paper is concerned with the existence of extremal mild solutions for Hilfer fractional evolution equations with nonlocal conditions in an ordered Banach space E.
Haide Gou, Yongxiang Li
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Molecular Oncology, EarlyView.Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler +3 more
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Lower and Upper Solutions for Singular Derivative Dependent Dirichlet Problem [PDF]
Mathematical Inequalities & Applications, 2001 The author develops the lower and upper solution method to work out the Dirichlet problem \[ u''+f(t,u,u')=0,\quad u(a)=0,\;u(b)=0, \] where \(f\) can be singular for \(t=a\), \(t=b\) and \(u=0\). Solutions are supposed to be in \(W^{1,1}(a,b)\cap W^{2,1}_{loc}(a,b)\).
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Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source
The method of upper and lower solutions for Caratheodory n-th order differential inclusions
Electronic Journal of Differential Equations, 2004 In this paper, we prove an existence theorem for n-th order differential inclusions under Caratheodory conditions. The existence of extremal solutions is also obtained under certain monotonicity condition of the multi-function.
Bupurao C. Dhage +2 more
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