Results 51 to 60 of about 1,003,788 (328)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

open access: yesFEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

Randomized complexity lower bounds [PDF]

open access: yesProceedings of the thirtieth annual ACM symposium on Theory of computing - STOC '98, 1998
The complexity lower bound (log N) is proved for randomized computation trees (over reals with branching signs f ; >g) for recognizing an arrangement or a polyhedron with N faces. A similar lower bound is proved for randomized computation trees over any zero-characteristic eld with branching signs f=; 6 =g for recognizing an arrangement.
openaire   +2 more sources

Asymptotic lower bounds in estimating jumps

open access: yes, 2014
We study the problem of the efficient estimation of the jumps for stochastic processes. We assume that the stochastic jump process $(X_t)_{t\in[0,1]}$ is observed discretely, with a sampling step of size $1/n$.
Clément, Emmanuelle   +2 more
core   +5 more sources

Lower Bounds for Structuring Unreliable Radio Networks [PDF]

open access: yes, 2014
In this paper, we study lower bounds for randomized solutions to the maximal independent set (MIS) and connected dominating set (CDS) problems in the dual graph model of radio networks---a generalization of the standard graph-based model that now ...
A. Clementi   +7 more
core   +1 more source

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

open access: yesFEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue   +6 more
wiley   +1 more source

Comparison of an improved self-consistent lower bound theory with Lehmann’s method for low-lying eigenvalues

open access: yesScientific Reports, 2021
Ritz eigenvalues only provide upper bounds for the energy levels, while obtaining lower bounds requires at least the calculation of the variances associated with these eigenvalues. The well-known Weinstein and Temple lower bounds based on the eigenvalues
Miklos Ronto   +2 more
doaj   +1 more source

Challenges in computational lower bounds [PDF]

open access: yes, 2013
We draw two incomplete, biased maps of challenges in computational complexity lower ...
Viola, Emanuele
core  

Radio Network Lower Bounds Made Easy

open access: yes, 2014
Theoreticians have studied distributed algorithms in the radio network model for close to three decades. A significant fraction of this work focuses on lower bounds for basic communication problems such as wake-up (symmetry breaking among an unknown set ...
Newport, Calvin
core   +1 more source

Lower bounds on concurrence and separability conditions [PDF]

open access: yes, 2007
We obtain analytical lower bounds on the concurrence of bipartite quantum systems in arbitrary dimensions related to the violation of separability conditions based on local uncertainty relations and on the Bloch representation of density matrices.
Julio I. de Vicente   +3 more
core   +4 more sources

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