Results 61 to 70 of about 5,110,730 (289)
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo +5 more
wiley +1 more source
Quantum algorithms and lower bounds for convex optimization [PDF]
While recent work suggests that quantum computers can speed up the solution of semidefinite programs, little is known about the quantum complexity of more general convex optimization.
Shouvanik Chakrabarti +3 more
doaj +1 more source
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Lower bounds by Birkhoff interpolation
In this paper we give lower bounds for the representation of real univariate polynomials as sums of powers of degree 1 polynomials. We present two families of polynomials of degree d such that the number of powers that are required in such a representation must be at least of order d. This is clearly optimal up to a constant factor.
Garcia-Marco, Ignacio, Koiran, Pascal
openaire +4 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Lower bounds for the energy of graphs
Let G be a finite simple undirected graph with n vertices and m edges. The energy of a graph G , denoted by E ( G ) , is defined as the sum of the absolute values of the eigenvalues of G .
Akbar Jahanbani
doaj +2 more sources
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
On lower bounds for the L_2-discrepancy
The L_2-discrepancy measures the irregularity of the distribution of a finite point set. In this note we prove lower bounds for the L_2 discrepancy of arbitrary N-point sets. Our main focus is on the two-dimensional case. Asymptotic upper and lower estimates of the L_2-discrepancy in dimension 2 are well-known and are of the sharp order sqrt(log N ...
Aicke Hinrichs, Lev Markhasin
openaire +3 more sources
Lower bounds for the bandwidth problem
The Bandwidth Problem seeks for a simultaneous permutation of the rows and columns of the adjacency matrix of a graph such that all nonzero entries are as close as possible to the main diagonal. This work focuses on investigating novel approaches to obtain lower bounds for the bandwidth problem.
Franz Rendl +2 more
openaire +5 more sources
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source

