Results 71 to 80 of about 4,836,614 (283)
Ancient karst at the eastern slope of the Middle Urals and the Early-Middle Carboniferous boundary
Литосфера, 2016 The paleokarst occurrences associated with Lower Carboniferous limestones in the east of the Middle Urals are considered. We analyse the nature of the Early-Middle Carboniferous boundary.
G. A. Mizens +3 more
doaj +2 more sources
The evolution of a sand-rich basin-fill sequence in the Pendleian (Namurian,E1c)of North-West England [PDF]
, 1988 The Bowland and Lancaster Fells Basins of north-west England contain a Pendleian El, sequence up to 650m thick, most of which is coarse clastic material.
Sims, Andrew Peter
core +3 more sources
E3S Web of Conferences, 2018 The Lower Paleozoic basins of eastern Poland have recently been the focus of intensive exploration for shale gas. In the Lublin Basin potential unconventional play is related to Lower Silurian source rocks.
Botor Dariusz
doaj +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
Molecular Oncology, EarlyView.High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira +7 more
wiley +1 more source
Литосфера, 2016 New data about the stable carbon and oxygen isotopic composition for the Frasnian/Famennian and Devonian/Carboniferous boundary intervals, as well as for middle and upper parts of the Tournasian Stage (the Lower Carboniferous), are represented in this ...
G. A. Mizens +4 more
doaj +2 more sources
Molecular Oncology, EarlyView.Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh +11 more
wiley +1 more source
Early diversification of seeds and seed-like structures
Carnets de Géologie, 2005 The seed habit is one of the most important evolutionary acquisition in plant evolution. It allowed colonisation of new ecological niches, leading to a level of diversification never observed before.
Prestianni Cyrille
doaj
Energy Exploration & Exploitation, 2018 A substantial amount of petroleum was recently discovered in the Carboniferous volcanic reservoir of the Chepaizi Uplift in the western Junggar Basin, yet the source is still indefinitive.
Youde Xu +4 more
doaj +1 more source