Results 81 to 90 of about 12,271 (224)

Remotely triggered scaffolds for controlled release of pharmaceuticals [PDF]

, 2013
Fe3O4-Au hybrid nanoparticles (HNPs) have shown increasing potential for biomedical applications such as image guided stimuli responsive drug delivery.
Hoskins, Clare, Lees, Martin R., McGarvey, David J., Roach, Paul, Ph.D.   +3 more
core   +2 more sources

Precise Regulation of Membrane Proteins: From Physical Technology to Biomolecular Strategy

Advanced Science, EarlyView.
This review summarizes the emerging strategies for the precise regulation of membrane proteins using physical stimuli and biomolecule‐based tools. These methods provide new insights into cell regulation and offer promising directions for future disease treatment.
Xiu Zhao, Qingqing Zhou, Mengli Li, Wen Zou, Zhenzhong Zhang, Jinjin Shi, Junjie Liu   +6 more
wiley   +1 more source

Influence of cyclodextrin on the UCST- and LCST-behavior of poly(2-methacrylamido-caprolactam)-co-(N,N-dimethylacrylamide)

Beilstein Journal of Organic Chemistry, 2014
The monomer 2-methacrylamido-caprolactam (4) was synthesized from methacryloyl chloride (3) and racemic α-amino-ε-caprolactam (2). Copolymerization of 4 with N,N-dimethylacrylamide (5) was carried out by a free-radical mechanism using 2,2’-azobis(2 ...
Alexander Burkhart, Helmut Ritter
doaj   +1 more source

Poly(NIPAM-co-MPS)-grafted multimodal porous silica nanoparticles as reverse thermoresponsive drug delivery system

Asian Journal of Pharmaceutical Sciences, 2017
Hybrid drug delivery systems (DDS) have been prepared by grafting poly(NIPAM-co-MPS) chains on multimodal porous silica nanoparticles having an inner mesoporous structure and an outer thin layer of micropores.
Sushilkumar A. Jadhav, Valentina Brunella, Dominique Scalarone, Gloria Berlier   +3 more
doaj   +1 more source

NIR‐Activatable Domino Cascade Catalysis Nanozyme Reactor for Multi‐Mechanism Synergistic Immunotherapy in Bladder Cancer

Advanced Science, EarlyView.
This study presents an intravesical delivery strategy of ferroptosis‐ and immunity‐inducing nanozyme‐loaded thermoresponsive hydrogels (FMCC@PNH) for enhanced bladder cancer therapy. Abstract Current intravesical therapies for bladder cancer after resection are limited by poor tissue penetration, off‐target effects, and insufficient efficacy.
Yongnan Jiang, Qingling Zhang, Yuhan Zhang, Xinlu Yu, Bo Jia, Yulong Dong, Yalong Wu, Kelong Fan, Xinquan Gu, Lei Ji, Wei Jiang, Bin Liu   +11 more
wiley   +1 more source

Kosmotropes and chaotropes: modelling preferential exclusion, binding and aggregate stability [PDF]

, 2004
Kosmotropic cosolvents added to an aqueous solution promote the aggregation of hydrophobic solute particles, while chaotropic cosolvents act to destabilise such aggregates. We discuss the mechanism for these phenomena within an adapted version of the two-
Moelbert, Susanne, Normand, B., Rios, Paolo De Los   +2 more
core   +1 more source

Stimuli-responsive electrospun fibers and their applications [PDF]

, 2011
Stimuli-responsive electrospun nanofibers are gaining considerable attention as highly versatile tools which offer great potential in the biomedical field.
Braeckmans, Kevin, De Smedt, Stefaan, Demeester, Jo, Huang, Chaobo, Lucas, Bart, Rejman, Joanna, Soenen, Stefaan   +6 more
core   +2 more sources

Stimuli‐Responsive Supramolecular Biomaterials for Cancer Theranostics

Advanced Science, EarlyView.
The ultimate goal of cancer theranostics is to get imaging agents and therapeutic cargo to tumor sites when and where they are required. “Smart” systems should be developed. This review discusses the characteristics of physiological stimuli, types and action modes of external stimuli, construction approaches and working principles, as well as ...
Wenting Hu, Binglin Ye, Guocan Yu, Feihe Huang, Zhengwei Mao   +4 more
wiley   +1 more source

Hydrophobic-electrostatic balance driving the LCST offset aggregation-redissolution behavior of N-alkylacrylamide-based ionic terpolymers [PDF]

, 2010
A series of random terpolymers composed of N-isopropylacrylamide (NIPAAm), 2-acrylamido-2-methyl-1-propanesulfonic acid (AMPS), and N-tert-butylacrylamide (NTBAAm) monomers were synthesized by free radical polymerization.
López Pérez, Paula M., Parra, Francisco, Pashkuleva, I., Reis, R. L., San Román, J., Silva, Ricardo M. P. da   +5 more
core   +1 more source

Control of osmotic pressure through CO₂-capture and release facilitated by the lower critical solution temperature (LCST) phase transition of acylated branched polyethylenimine

RSC Advances, 2016
A solution of acylated polyethylenimine absorbs CO2at low temperatures and draws water from high-salt saline due to the high osmotic pressure, while it liberates CO2after phase separation by mild heating and releases water into low-salt saline.
Jeongseon Park, Minwoo Noh, Min Keun Chey, Yeongbong Mok, Ji-Hun Seo, Yan Lee   +5 more
openaire   +1 more source