Results 31 to 40 of about 5,081,141 (297)

Factors affecting contralateral extremity following lower-extremity major amputation

open access: yesIndian Journal of Vascular and Endovascular Surgery, 2021
Objective: Lower-extremity amputation is performed in patients who are at risk due to acute limb ischemia (ALI), chronic limb-threatening ischemia (CLTI), and diabetic foot infections, yet the proportion of patients who progress to amputation of their ...
B Nishan   +4 more
doaj   +1 more source

Serum Myonectin Levels Are Positively Associated With Physical Function and Lower Frailty‐Related Limitation in Maintenance Hemodialysis Patients: A Cross‐Sectional Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Maintenance hemodialysis (MHD) patients frequently suffer from frailty, characterized by reduced physical function and poor prognosis. Myokines, such as myonectin, secreted by muscle, are emerging regulators of systemic health. This study investigated the relationship between serum myonectin, adipokines (adiponectin, omentin), and ...
Kenichi Kono   +7 more
wiley   +1 more source

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa   +7 more
wiley   +1 more source

Development and Validation of an Algorithm to Objectively Quantify Adherence to Offloading Interventions

open access: yesJournal of Foot and Ankle Research
Background Diabetic foot ulcers require offloading for healing. However, adherence with removable offloading devices is often poor. Prior objective measures of adherence yielded important behavioral insights, despite substantial methodological ...
Sai V. Yalla   +4 more
doaj   +1 more source

Total talus metallosis with ankle arthroplasty

open access: yesFoot & Ankle Surgery: Techniques, Reports & Cases
Total ankle total talus replacement (TATTR) is gaining popularity in the foot and ankle surgery world in patients with end-stage ankle arthritis with concomitant pathology to the talus.
Thomas Milisits, DPM, MPH   +4 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Association of Risk-Taking Behaviors, Vestibular Provocation and Action Boundary Perception Following Sport-Related Concussion in Adolescents

open access: yesBrain Sciences
Background/Objectives: The purpose of this study was to evaluate the association between risk-taking behaviors, vestibular symptoms/impairment and perception–action coupling behavior in recently concussed adolescents. Methods: This study utilized a cross-
Shawn R. Eagle   +3 more
doaj   +1 more source

Efficacy and patient satisfaction regarding lymphovenous bypass with sleeve-in anastomosis for extremity lymphedema

open access: yesArchives of Plastic Surgery, 2019
Background When performing lymphovenous anastomosis, it is sometimes difficult to find venules in the proximity of an ideal lymphatic vessel that have a similar diameter to that of the lymphatic vessel. In this situation, larger venules can be used.
Jae-Ho Chung   +5 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Free Flap Salvage in Lower Extremity Reconstruction via Use of Contralateral Lower Extremity Recipient Vessels

open access: yesJournal of Reconstructive Microsurgery Open, 2016
Soft-tissue coverage after complex distal lower extremity trauma is often difficult due to limited local flap options and injury to potential recipient vessels when considering microsurgical reconstruction.
Katelyn G. Bennett   +3 more
doaj   +1 more source

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