Results 41 to 50 of about 5,081,141 (297)

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Modular lower extremity prosthetics

South African Journal of Physiotherapy, 1971
No abstract available.
J. Foort
doaj   +1 more source

Lower Extremity Nerve Function in Patients With Lower Extremity Ischemia [PDF]

Archives of Internal Medicine, 2006
We determined whether lower extremity ischemia, as measured by the ankle brachial index (ABI), is associated with impaired lower extremity nerve function.Participants included 478 persons with peripheral arterial disease (PAD) identified from noninvasive vascular laboratories and 292 persons without PAD identified from a general medicine practice and ...
Mary M, McDermott, Robert, Sufit, Takashi, Nishida, Jack M, Guralnik, Luigi, Ferrucci, Lu, Tian, Kiang, Liu, Jin, Tan, William H, Pearce, Joseph R, Schneider, Leena, Sharma, Michael H, Criqui   +11 more
openaire   +2 more sources

Effects of Noxious Versus Innocuous Thermal Stimulation on Lower Extremity Motor Recovery 3 Months After Stroke

, 2017
Objective: To examine the effects of thermal stimulation (TS) on the lower extremity (LE) movement and function in patients with stroke. ;Design: A double-blinded randomized controlled trial. ;Setting: A university hospital. ;Participants: Patients (N=34)
Hsu, Hsin-Wen; Lee, Chia-Ling; Hsu, Miao-Ju; Wu, Hung-Chia; Lin, Roxane; Hsieh, Ching-Lin; Lin, Jau-Hong
core   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Structural integrity of custom-designed additive manufactured prosthetic sockets compared to traditional sockets

Results in Materials
Over the past decades, the number of patients with lower extremity amputation increased world-wide. The increasing rate of patients, particularly in developing countries, has led to limited access to clinics and services for prosthetic and orthotic care.
Sunjung Kim, Sai V. Yalla, Sagar Shetty, Noah J. Rosenblatt   +3 more
doaj   +1 more source

Chlamydia psittaci Pneumonia Complicated with Lower Extremity Atherosclerotic Occlusive Disease

, 2023
YongHong He,1 SongPing Wang,1 Jun Deng,1 Qian Pu,2 Hong Chen,3 Lan Huang3 1Department of Respiratory Medicine and Critical Care Medicine, The Affiliated Hospital of Southwest Medical University, Luzhou City, Sichuan Province, 646000, People’s Republic of
Pu Q, He Y, Wang S, Deng J, Chen H, Huang L   +5 more
core  

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

The Impact of Cast Walker Design on Metabolic Costs of Walking and Perceived Exertion

Diabetology
Background/Objectives: Cast walkers (CWs) are often prescribed to offload diabetic foot ulcers (DFUs). However, their mass, the degree of ankle immobilization and the limb length discrepancy they induce may increase the energetic demands of walking ...
Emily Standage, Dylan Tookey, Uchechukwu Ukachukwu, Marco Avalos, Ryan T. Crews, Noah J. Rosenblatt   +5 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source