Results 61 to 70 of about 5,404,147 (255)

Nanometer Layer Coating to Lactose Particles for Optimization of Dexamethasone Pulmonary Delivery

Advanced Science, EarlyView.
Nanometer layer coating (NLC) was investigated and its mechanism illustrated by advanced characterization techniques. The effects and application for the inhalation of dexamethasone (DEX) were demonstrated through in vitro and in vivo evaluation. This approach increased DEX bioavailability and enabled the dose to be reduced to 1/30 of the intravenous ...
Qin Nie, Jiahe Liu, Xiangyu Zhao, Siying Yang, Han Sun, Bingqian Jia, Xiaohong Ren, Xintao Chen, Lixin Sun, Li Wu, Caifen Wang, Jiwen Zhang   +11 more
wiley   +1 more source

Fatores preditivos de óbito em pacientes internados por hemorragia digestiva alta no Hospital Universitário - Universidade Federal de Santa catarina. [PDF]

, 1999
Trabalho de Conclusão de Curso - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Departamento de Clínica Médica, Curso de Medicina, Florianópolis ...
Malluta, Éverson Fernando
core  

A C‐Nucleoside Analogue of Cordycepin With High Metabolic Stability and Potent Anti‐Psoriatic Activity via Microneedle Delivery

Advanced Science, EarlyView.
This work identified CPD3a as a potent, stable C‐nucleoside cordycepin derivative. When formulated into microneedle array for topical treatment, it ameliorated psoriasis by rebalancing immunity and enhancing antioxidant defenses. ABSTRACT Psoriasis is a chronic inflammatory disorder characterized by immune dysregulation and epidermal hyperplasia ...
Wenfang Pan, Xinyue Shao, Yuanchen Zhong, Xujie Sun, Lixuan Yin, Zongyan He, Tianqun Lang, Yuanchao Xie   +7 more
wiley   +1 more source

A Rare Cause of Upper Gastrointestinal Bleeding: Aorta-Esophageal Fistula

Aortoesophageal fistula (AEF) is rarely seen in gastroenterology practice. It is a very fatal condition. Common causes of AEF are aortic aneurysms and dissections, foreign body ingestion, traumatic aortic injuries, ruptured penetrating aortic ulcers ...
Halil Çapar, Duran Deha Çetin, Bünyamin Sarıtaş, Ayşe Yıldırım Çelikdemir, Şehmus Ölmez, Ferid Cereb   +5 more
core   +1 more source

Colonic angiodysplasia in a 34-year-old Nigerian: A case report with a review of literature

Ibom Medical Journal
Angiodysplasia is an arteriovenous malformation characterized by abnormal, tortuous, dilated small blood vessels in the mucosa and submucosa. It commonly occurs in the colon.
Eboreime OO, Umeaku U, Uchendu OJ, Yovwin G, Nwajei IA, Sokoh AC, Chukwuebuni U   +6 more
doaj   +1 more source

Inflammation Unchecked: Concurrent Kawasaki Disease and Stevens‐Johnson Syndrome in an 18‐Month‐Old Child

Arthritis Care &Research, EarlyView.
Catherine Deffendall, Jodi Backalar, Elizabeth Acevedo Zapata, Adriana Della Porta, Lorin Bibb, Tyler Reese, Charlotte M. Brown   +6 more
wiley   +1 more source

Uhrf1‐Mediated PKM2 Degradation via Ubiquitination Alleviates Inflammation and Pyroptosis in Inflammatory Bowel Disease

Advanced Science, EarlyView.
Uhrf1‐mediated PKM2 ubiquitination and degradation repressed the nuclear translocation of PKM2, and EPT served as a molecular glue capable of targeting the Uhrf1–PKM2 complex to alleviate the IBD course, suggesting that the Uhrf1–PKM2 axis was a previously unrecognized strategy for treating IBD.
Juan Zhang, Xin‐Rong Xu, Hui‐Lin Zhang, Qi‐Meng Zhu, Xin‐Yuan Li, Xi‐Peng Shang, Jing‐Hui Du, Christophe Morisseau, Feng Qiu, Cheng‐Peng Sun   +9 more
wiley   +1 more source

Hemorragia digestiva baja en el adulto: conceptos claves en la actualización del diagnóstico y tratamiento

Revista Médica Clínica Las Condes
Resumen: La hemorragia digestiva baja (HDB) es una causa frecuente de consulta de urgencia y hospitalización, especialmente en adultos mayores con antecedentes de enfermedad cardiovascular y uso de tratamiento antitrombótico.
Roberto Salas, MD, Gonzalo Rebolledo, MD, Alejandro J. Zarate, MD   +2 more
doaj   +1 more source

Oral Nanomicelle‐Mediated Sequential Butyrate Production in the Intestine for Ulcerative Colitis and Immunosuppression Treatment

Advanced Science, EarlyView.
After oral administration, inodorous GLU‐BA self‐assembles into nanomicelles in aqueous environments to resist premature gastric adsorption. Upon reaching the intestine, endogenous esterases rapidly cleave the built‐in ester bonds in these nanomicelles to release BA and GLU, with GLU further metabolized by gut microbiota to gradually generate BA ...
Feifei Xin, Zhike Xie, Danyue Zhao, Lin Yang, Yiqun Wan, Zuwei Liu, Situ Xiong, Ying Zhang, Lei Feng, Hao Wan   +9 more
wiley   +1 more source

Jejunal Diverticula Causing Unusual Massive Lower Gastrointestinal Bleeding

International Journal of Gerontology, 2008
Jejunal diverticula are rare and difficult to diagnose. They are often asymptomatic, but they may infrequently cause serious acute complications, such as diverticulitis with or without perforation, volvulus, intussusception, or hemorrhage.
Chiong-Hee Wong, I-Tsung Lin, Shou-Chuan Shih, Wen-Hsinug Chang, Horng-Yuan Wang   +4 more
doaj   +1 more source