Results 91 to 100 of about 5,989,717 (278)

Yoda1‐Functionalized Nanozymes Coordinate Piezo1 Activation and Mitochondrial Protection to Reprogram the Diabetic Osteoimmune Micromilieu and Promote Vascularized Bone Repair

Advanced Science, EarlyView.
Diabetic bone defects remain a critical clinical challenge. A 3D‐printed BCPG‐MF@Y scaffold, embedding Yoda1‐functionalized manganese dioxide‐ferritin nanozymes, scavenges mtROS, suppresses the cGAS–STING pathway, and reverses cellular senescence, while Yoda1 activates Piezo1 to direct BMSCs fate to synergistically reprogram the osteoimmune ...
Qing‐Song Deng, Ang Wang, Ren Zhang, Xu‐Ran Li, Po‐Lin Liu, Shu‐Hang He, Zi‐Yin Han, Zhi‐Han Shen, Zhan‐Ying Wei, Chang‐Ru Zhang, Fei Wang, Helen Dawes, Jian Lu, Tong‐He Zhu, Jin‐Zhong Zhao, Shang‐Chun Guo, Shi‐Cong Tao   +16 more
wiley   +1 more source

Mechanical Distraction Engages a Neuro‐Immune Program to Drive Regenerative Soft‐Tissue Healing in Ilizarov Bone Transport

Advanced Science, EarlyView.
Ilizarov bone transport accelerates healing of soft‐tissue wounds through unclear mechanisms. In a rat model, sustained mechanical distraction elicits calcitonin gene‐related peptide (CGRP)‐dominant sensory reinnervation, creating a niche that shifts immune cells from inflammatory to repair‐promoting states and speeds re‐epithelialization.
Yueliang Zhu, Jiayu Chen, Xuehuan Wen, Kaijia Tang, Ling Gao, Chenxing Wang, Yixuan Feng, Si‐He Qin, Tao Chen, Xiaohua Yu   +9 more
wiley   +1 more source

Trajectory Optimization of Lower Extremity Rehabilitation Robots Based on Cycloid

Jixie chuandong
With the rapid development of modern robotics and medical industry, the use of rehabilitation robots for the treatment of patients with lower limb sports injuries has become one of the research hotspots at home and abroad.
Cui Bingyan, Zeng Hongtai, Yang Zhongyuan, Gui Xiaogeng, Li He, Wang Jingwei   +5 more
doaj  

Targeting Mitochondrial Redox Signaling Promotes Neuroregeneration and Functional Recovery in a Multiple Sclerosis Model

Advanced Science, EarlyView.
Modulation of mitochondrial redox signaling by furapyrrodole activates CYB5R3 and suppresses Notch signaling, unlocking the regenerative potential of endogenous neural progenitor cells. This approach promotes neurogenesis, oligodendrogenesis, and remyelination, thereby improving neuronal function in a mouse model of multiple sclerosis and identifying ...
Yuki Narushima, Joshua Saylor, Shun Saito, Jinyan Zhou, Haruka Kawano, Shehata Anwar, Haruki Oba, Rachel Huezo, Miyu Okano, Haruki Matsuda, Makoto Kawatani, Kaori Honda, Hiroyuki Osada, Yuta Kikuchi, Masahito Ohue, Masami Ishibashi, Takayoshi Arai, Makoto Inoue, Midori A. Arai   +18 more
wiley   +1 more source

Investigating Current Notion on Virtual Reality Rehabilitation Approach on Post Operative Lower Extremity Conditions: A Narrative Review

Journal of Modern Rehabilitation
Introduction: Lower extremity surgeries, such as total knee arthroplasty, total hip arthroplasty (THA), and anterior cruciate ligament reconstruction require extensive rehabilitation to restore mobility and function.
Om Wadhokar, Vanshika Tandon, Sakshi Yede, Jayantika Bhardwaj, Seema Saini, Tushar Palekar   +5 more
doaj   +1 more source

A High‐Precision Dynamic Movement Recognition Algorithm Using Multimodal Biological Signals for Human–Machine Interaction

Advanced Intelligent Systems, Volume 7, Issue 3, March 2025.
This article describes a multimodal fusion data acquisition and processing system about electromyography for dynamic movement recognition and bioelectrical impedance for key posture recognition. In addition, a new dynamic–static fusion algorithm strategy is designed.
Chenhao Cao, Gang Ma, Zelin Chen, Yiming Ouyang, Hu Jin, Shiwu Zhang   +5 more
wiley   +1 more source

Fatigue‐Driven Adaptive Assistance for a Semi‐Active Upper‐Limb Occupational Exoskeleton

Advanced Intelligent Systems, EarlyView.
Physical fatigue during a physical activity is estimated in real time to enable adaptive exoskeleton assistance. By continuously adjusting the level of support according to the user’s fatigue, this approach reduces physical demand and provides a pathway toward personalized exoskeleton assistance.
Seemab Zakir, Lorenzo Grazi, Simone Prisinzano, Francesco Giovacchini, Nicola Vitiello, Emilio Trigili, Simona Crea   +6 more
wiley   +1 more source

An Integrated Fabric‐Pneumatic Soft Sensing System for Multi‐Site Muscle Activity Decoding

Advanced Intelligent Systems, EarlyView.
Fabric‐pneumatic chambers convert muscle deformation into pressure signals without electronics at the body‐contact sensing interface. A unified processing pipeline enables static posture classification, continuous elbow‐angle estimation, forearm gesture recognition, and knee‐movement detection across three anatomical sites.
Qifeng Xun, Jonathan William Ambrose, Quan Xiong, Chen Hua Yeow   +3 more
wiley   +1 more source

Minimalist versus conventional running shoes : effects on lower limb injury incidence, pain and muscle function experienced distance runners [PDF]

, 2013
Includes abstract.Includes bibliographical references.The aim of this randomised clinical trial over 12 weeks was to determine if the gradual transition (accompanied by calf muscle training), from conventional to minimalist running shoes 1) increased the
Marshall, Charlene
core   +1 more source

The Key Technologies and Technological Evolution Mechanisms of Robotic Systems for Fracture Reduction Surgery

Advanced Intelligent Systems, EarlyView.
This review traces three decades of technological evolution in robot‐assisted fracture reduction systems, from early robotic concepts to clinically oriented platforms. Key advances in robotic architecture, navigation, path planning, interaction control, and surgical integration are summarized, while current translational challenges and future ...
Shaolong Kuang, Xiaoyang Hu, Jianhua Li, Fang Wang, Xue Zhang, Lihai Zhang   +5 more
wiley   +1 more source