Results 121 to 130 of about 5,989,717 (278)

A mouse model of mechanical stress injury to the basal ganglia using thermosensitive PNIPAM hydrogel for intracerebral hemorrhage research

open access: yesAnimal Models and Experimental Medicine, EarlyView.
In this study, we established a novel mouse model of intracerebral hemorrhage (ICH) by stereotactically injecting thermosensitive PNIPAM hydrogel into the internal capsule to impose localized mechanical stress on the corticospinal tract, which provides a straightforward and reproducible tool for preclinical studies on focal mechanical stress–induced ...
Mingxi Li   +11 more
wiley   +1 more source

Rate and Shape of Functional Decline in Amyotrophic Lateral Sclerosis Identify Clinically Distinct Amyotrophic Lateral Sclerosis Phenotypes

open access: yesAnnals of Neurology, EarlyView.
Objective The ALS Functional Rating Scale–Revised decline rate compresses trajectory shape into a single number, potentially missing distinct phenotypes. We tested whether shape identifies phenotypes that rate does not distinguish, and whether post‐hoc analysis recovers a hidden ultrarapid subgroup. Methods From the Piemonte and Valle d'Aosta register (
Andrea Calvo   +20 more
wiley   +1 more source

Rehabilitation training robot using mirror therapy for the upper and lower limb after stroke: a prospective cohort study

open access: yesJournal of NeuroEngineering and Rehabilitation
Background This prospective cohort study was designed to investigate and compare the effectiveness of rehabilitation training robots versus conventional rehabilitation training on stroke survivors by monitoring alterations in brain network of stroke ...
Xixi Wu   +7 more
doaj   +1 more source

Preoperative Sagittal Tibial Tubercle‐Trochlear Groove Distance Predicts Postoperative Outcome in Patients Undergoing Combined Trochleoplasty and Medial Patellofemoral Ligament Reconstruction

open access: yesArthroscopy, EarlyView.
Purpose To evaluate the association between the preoperative sagittal tibial tubercle‐trochlear groove (sTTTG) distance and postoperative patient‐reported outcomes after combined patellofemoral ligament reconstruction and deepening trochleoplasty in patients with recurrent lateral patellar instability and high‐grade trochlear dysplasia.
Sebastian Schmidt   +5 more
wiley   +1 more source

The Forgotten Joint Score Shows High Correlation With Established Anterior Cruciate Ligament Reconstruction Patient‐Reported Outcome Measures While Capturing Joint Awareness and Functional Recovery: A Systematic Review

open access: yesArthroscopy, EarlyView.
Purpose To systematically review and analyze the existing literature on the use of the Forgotten Joint Score‐12 (FJS‐12) in patients undergoing anterior cruciate ligament reconstruction (ACLR), with the aim of evaluating its effectiveness as a complementary tool to traditional patient‐reported outcome measures (PROMs) in assessing postoperative ...
Helena Son   +6 more
wiley   +1 more source

Satisfaction with cosmesis and priorities for cosmesis design reported by lower limb amputees in the United Kingdom : instrument development and results [PDF]

open access: yes, 2013
Study Design: Cross sectional questionnaire study. Background: Amputee satisfaction with cosmesis and the importance they place on cosmesis design has not been published in the literature.
Corney, Jonathan   +3 more
core  

The Use of Unloader Bracing in the Management of Knee Osteoarthritis: A Modified Delphi Consensus Study

open access: yesArthroscopy, EarlyView.
Purpose To develop international expert consensus on the role of unloader bracing in the management of tibiofemoral osteoarthritis (OA) by addressing indications, contraindications, clinical evaluation, perioperative applications, and research priorities using a modified Delphi methodology.
Jonathan T. Super   +37 more
wiley   +1 more source

Unloader Bracing Is a Biomechanically Rational and Clinically Useful Intervention in Selected Patients With Tibiofemoral Joint Cartilage Pathology: A Modified Delphi Consensus Study

open access: yesArthroscopy, EarlyView.
Purpose To establish an international expert consensus on the role of unloader bracing in the management of focal tibiofemoral cartilage lesions using Delphi methodology to inform clinical decision‐making in both nonoperative and operative contexts and identify future research priorities.
Jonathan T. Super   +37 more
wiley   +1 more source

Current Research Status of Active-Assist Lower Limb Rehabilitation Exoskeleton Robots

open access: yesJixie chuandong
It is crucial to develop active assistant lower limb rehabilitation exoskeleton robots in light of the current situation of population aging and the sharp rise in the number of people with lower limb disorders.
Guo Yifeng   +4 more
doaj   +2 more sources

Neuromuscular Electric Stimulation Improves Early Isometric Knee Strength After Anterior Cruciate Ligament Reconstruction and Repair: A Meta‐analysis of Randomized Controlled Trials

open access: yesArthroscopy, EarlyView.
Purpose To assess the effectiveness of neuromuscular electrical stimulation (NMES) on quadriceps strength and knee function after anterior cruciate ligament surgery. Methods A comprehensive search of PubMed, Ovid MEDLINE, and Embase from inception until February 2025 was conducted.
Anser Daud   +6 more
wiley   +1 more source

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