Results 111 to 120 of about 346,142 (364)

Population pharmacokinetic modelling of prednisolone in systemic lupus erythematosus patients: Analysis of exposure and disease activity

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aims Prednisone is a widely used glucocorticoid in the treatment of lupus, although its dosing is often determined empirically. Prednisolone, the active metabolite of prednisone, is found in its free form in the serum. The goal of this study was to develop a population pharmacokinetic model in patients with systemic lupus erythematosus (SLE ...
Naïm Bouazza   +26 more
wiley   +1 more source

AI-aided Geometric Design of Anti-infection Catheters [PDF]

open access: yesarXiv, 2023
Bacteria can swim upstream due to hydrodynamic interactions with the fluid flow in a narrow tube, and pose a clinical threat of urinary tract infection to patients implanted with catheters. Coatings and structured surfaces have been proposed as a way to suppress bacterial contamination in catheters.
arxiv  

Prevalence, affecting factors and relationship with toileting behaviors of lower urinary tract symptoms in pregnant women: a cross-sectional study [PDF]

open access: yes, 2023
OBJECTIVE: This study aimed to determine factors associated with lower urinary tract symptoms and their prevalence in pregnant women, and to examine the relationship between these symptoms and toileting behaviorPATIENTS AND METHODS: The study included ...
Destegul, E.   +3 more
core  

CNN-Based Automatic Urinary Particles Recognition [PDF]

open access: yes, 2018
The urine sediment analysis of particles in microscopic images can assist physicians in evaluating patients with renal and urinary tract diseases. Manual urine sediment examination is labor-intensive, subjective and time-consuming, and the traditional automatic algorithms often extract the hand-crafted features for recognition.
arxiv   +1 more source

Artificial Intelligence-based Eosinophil Counting in Gastrointestinal Biopsies [PDF]

open access: yesarXiv, 2022
Normally eosinophils are present in the gastrointestinal (GI) tract of healthy individuals. When the eosinophils increase beyond their usual amount in the GI tract, a patient gets varied symptoms. Clinicians find it difficult to diagnose this condition called eosinophilia. Early diagnosis can help in treating patients.
arxiv  

The pathobiology of subclinical pyelonephritis—An experimental evaluation [PDF]

open access: yes, 1992
The pathobiology of subclinical pyelonephritis—An experimental evaluation. Clinical studies have demonstrated a poor correlation between localization tests, which are designed to determine the site of urinary tract infection, and symptoms of upper ...
Findon, Glenne   +3 more
core   +1 more source

Intravesical therapy for lower urinary tract symptoms

open access: yesUrological Science, 2012
AbstractIntravesical (local) therapy for diseases emanating from the bladder is similar to the commonplace management of ocular diseases using eyedrops. The existing intravesical therapy involves administering dosage forms directly into the bladder (through a catheter). This mode of treatment is routine in the bladder cancer by instillation of bacillus
Pradeep Tyagi   +3 more
openaire   +2 more sources

Teachers', parents', and pupils' perceptions and described experiences of toilet provisions and practices within English schools

open access: yesBritish Educational Research Journal, EarlyView.
Abstract This paper explores teachers', parents' and pupils' perceptions and described experiences of school toilet policies, provisions and practices within state‐funded primary (5–11 years) and secondary (11–16 years) schools in England. In doing so, this research critically examines how school‐specific policies and toilet provisions influence ...
Matthew J. Green   +3 more
wiley   +1 more source

Ultrasound Estimated Bladder Weight in Asymptomatic Adult Females

open access: yesUrology Journal, 2012
PURPOSE: To estimate the bladder weight by automated ultrasound method (BladderScan BVM 9500) in adult females without lower urinary tract symptoms and to assess both the intra-observer and interobserver reproducibility of this method.
Ghadeer Al-Shaikh, Hazem Al-Mandeel
doaj  

An open‐label, single‐arm, multicenter, phase II trial of bireociclib as monotherapy for heavily pretreated HR‐positive, HER2‐negative advanced breast cancer patients: BRIGHT‐1 trial

open access: yesCancer Communications, EarlyView.
Abstract Background Bireociclib (XZP‐3287) is a novel selective cyclin‐dependent kinase 4 and 6 (CDK4/6) inhibitor, with a favorable safety profile demonstrated in preclinical and phase I studies. BRIGHT‐1 aimed to further explore the efficacy and safety of bireociclib monotherapy in patients with locally advanced, recurrent or metastatic, hormone ...
Jiayu Wang   +18 more
wiley   +1 more source

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