Results 91 to 100 of about 74,325 (301)

Description of the rate-limiting hydrogen tunneling mechanism for plant 9- and 13-lipoxygenases. [PDF]

Protein Sci
Abstract Soybean lipoxygenase (GmLOX1), a plant 13‐LOX, has long been considered a model protein for non‐trivial, quantum hydrogen tunneling in enzyme catalysis. Hydrogen tunneling mechanisms have also been confirmed for LOXs across mammalian, fungal, and bacterial kingdoms.
Kockler A, Ray K, King J, Anderson E, Walker J, Gilbert N, Horn P, Offenbacher AR.   +7 more
europepmc   +2 more sources

Thiamine seed treatment enhances LOX expression, promotes growth and induces downy mildew disease resistance in pearl millet

, 2011
Seeds of pearl millet Pennisetum glaucum (L). R.Br.] susceptible cv. 7042S were treated with thiamine at 5, 10, 15, 20 and 25 mM concentrations and growth promotion and downy mildew resistance were tested.
Sudisha, J., Shekar Shetty, H., H. G. Pushpalatha, J. Sudisha, N. P. Geetha, H. Shekar Shetty, Pushpalatha, H. G., Shetty, H. S., Amruthesh, K. N., H. Shetty, K. N. Amruthesh, Geetha, N. P.   +11 more
core   +1 more source

From Inflammatory Bowel Disease to Cancer: Gut Microbiota–Immune Microenvironment Crosstalk and Natural Product‐Based Therapeutic Opportunities

Cancer Nexus, EarlyView.
ABSTRACT Inflammatory bowel disease (IBD), primarily Crohn's disease and ulcerative colitis, is a chronic relapsing inflammatory disorder of the gastrointestinal tract and an important risk factor for IBD‐associated cancer. Increasing evidence suggests that gut microbiota dysbiosis, epithelial barrier dysfunction, and immune microenvironment remodeling
Xue Zhang, Chongchong Gao, Rui Jiang, Zijian Wu, Jian Bai   +4 more
wiley   +1 more source

Applying internal coordinate mechanics to model the interactions between 8R-lipoxygenase and its substrate

BMC Bioinformatics, 2010
Background Lipoxygenases (LOX) play pivotal roles in the biosynthesis of leukotrienes and other biologically active potent signalling compounds. Developing inhibitors for LOX is of high interest to researchers.
Khosravi Ebrahim, Du Tianchuan, Bai Shuju   +2 more
doaj   +1 more source

Structures of LOX inhibitors.

, 2013
Structures of LOX inhibitors.
Andrew G. S. Warrilow (426168), Steven C. Perry (426169), Ganesha Rai (236758), Josie E. Parker (215857), David J. Maloney (126223), Ajit Jadhav (85100), Christopher J. Smyrniotis (426170), Theodore R. Holman (426172), Eric K. Hoobler (426167), Anton Simeonov (85099), Diane E. Kelly (215870), S. L. Kelly (426171)   +11 more
core   +1 more source

LOX (lysyl oxidase) [PDF]

, 2010
Review on LOX (lysyl oxidase), with data on DNA, on the protein encoded, and where the gene is ...
SFT Fong, KSK Fong, K Csiszar, Fong, KSK, Fong, SFT, Csiszar, K   +5 more
core   +1 more source

The role of Rho GTPases in facial morphogenesis

Developmental Dynamics, EarlyView.
The role of small GTPases, RHOA, RAC1, and CDC42 and pathway mediators is reviewed in the context of embryonic facial development. Lip fusion requires cytoskeletal remodeling during morphogenesis of the facial processes and during lip fusion. Fnm, frontonasal mass; lnp, lateral nasal process; mnp, medial nasal process; mxp, maxillary process; np, nasal
Isra Ibrahim, Joy M. Richman
wiley   +1 more source

The role of the LOX family in cancer

European Journal of Cell Biology
Lysyl oxidase (LOXs) are copper-dependent enzymes traditionally known for catalyzing the cross-linking of collagen and elastin, thereby ensuring extracellular matrix (ECM) stability. However, growing evidence reveals that their biological functions extend far beyond ECM remodeling.
Diego Liviu, Boaru, Diego, De Leon-Oliva, Oscar, Fraile-Martinez, Patricia, De Castro-Martinez, Cielo, Garcia-Montero, Connie, Ferrara-Coppola, Majd N, Michael Alhaddadin, Silvestra, Barrena-Blázquez, Cristina De Las, Peñas-González, Noemí, Holgado-Tirado, Mónica, Tordesillas-Vicente, Diego, Torres-Carranza, Laura, Lopez-Gonzalez, Raul, Diaz-Pedrero, Melchor, Alvarez-Mon, Miguel A, Saez, Miguel A, Ortega   +16 more
openaire   +2 more sources

Pulsed Light Technology in Food Safety and Preservation: Principles, Applications, and Future Directions

Food Chemistry International, EarlyView.
Pulsed light technology uses short high‐intensity broad‐spectrum flashes (200–1100 nm) to inactivate microbes via DNA damage. It preserves food quality, extends shelf life, and works on liquids, meats, and produce, often combined with other hurdles for enhanced efficacy.
Abdul Mueez Ahmad, Laiba Younas, Fatima Javed, Rimsha Amjad, Muhammad Tayyab Raza   +4 more
wiley   +1 more source

Lysyl Oxidase in Ectopic Cardiovascular Calcification: Role of Oxidative Stress

Antioxidants
Lysyl oxidase (LOX)-mediated extracellular matrix crosslinking modulates calcification in atherosclerosis and aortic valve disease; however, this enzyme also induces oxidative stress.
Carme Ballester-Servera, Judith Alonso, Laia Cañes, Paula Vázquez-Sufuentes, Ana B. García-Redondo, Cristina Rodríguez, José Martínez-González   +6 more
doaj   +1 more source