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Inflammatory milieu and role of epigenetic modifications in high-grade serous ovarian cancer. [PDF]

open access: yesClin Epigenetics
Pradhan S   +6 more
europepmc   +1 more source

Lysophosphatidic acid-induced Arf6-driven macropinocytosis of CD147<sup>+</sup> extracellular vesicles promotes sorafenib resistance of hepatocellular carcinoma. [PDF]

open access: yesInt J Biol Sci
Qian L   +13 more
europepmc   +1 more source
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Autotaxin Facilitates Selective LPA Receptor Signaling

SSRN Electronic Journal, 2022
SUMMARYAutotaxin (ATX; ENPP2) produces the lipid mediator lysophosphatidic acid (LPA) that signals through disparate EDG (LPA1-3) and P2Y (LPA4-6) G protein-coupled receptors. ATX/LPA promote several (patho)physiological processes, including in pulmonary fibrosis, thus serving as attractive drug targets.
Fernando Salgado-Polo   +8 more
openaire   +1 more source

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