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Impact of tumor necrosis factor-alpha and lysophosphatidic acid on the behavior of ovarian cancer cells in a three-dimensional collagen hydrogel. [PDF]
Tino AB +3 more
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Inflammatory milieu and role of epigenetic modifications in high-grade serous ovarian cancer. [PDF]
Pradhan S +6 more
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Lysophosphatidic acid-induced Arf6-driven macropinocytosis of CD147<sup>+</sup> extracellular vesicles promotes sorafenib resistance of hepatocellular carcinoma. [PDF]
Qian L +13 more
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Lipoprotein(a) and the Vascular Redox Interface: Linking Arteriosclerosis, Thrombosis, and Vascular Biology. [PDF]
Zubiran R, Remaley AT.
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Autotaxin Facilitates Selective LPA Receptor Signaling
SSRN Electronic Journal, 2022SUMMARYAutotaxin (ATX; ENPP2) produces the lipid mediator lysophosphatidic acid (LPA) that signals through disparate EDG (LPA1-3) and P2Y (LPA4-6) G protein-coupled receptors. ATX/LPA promote several (patho)physiological processes, including in pulmonary fibrosis, thus serving as attractive drug targets.
Fernando Salgado-Polo +8 more
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