ABSTRACT Background and Aims Nurses in plateau areas face unique stressors, yet little is known about their perceived stress patterns. This study aimed to identify the latent profiles of perceived stress among nurses in plateau areas, explore associated factors, and compare work engagement across different profiles.
Huamin Chu, Qian Gao, Lin Chen
wiley +1 more source
Metabolic reprogramming in tumor-associated cells of hematologic malignancies: mechanisms, crosstalk networks, and therapeutic implications in the tumor microenvironment. [PDF]
Hong Z, Wu Y, Liu W, Li D, Xu J.
europepmc +1 more source
Canoe full of hot paddlers: TRPV1 neurons steering cardiorespiratory control
The Journal of Physiology, EarlyView.
Richard J. A. Wilson +1 more
wiley +1 more source
ABSTRACT Lipid metabolism reprogramming is a hallmark of cancer, yet the global lipidome of cancer cells and their extracellular vesicles (EVs) remains poorly understood. Using mass spectrometry, we analyzed the lipid profiles of a panel of human cancer and non‐cancer cell lines along with their secreted EVs.
Noélie Douanne +14 more
wiley +1 more source
Lysophosphatidic acid-mediated NF-κB activation promotes FOXC2 expression essential for lymphatic valve development. [PDF]
Yasuda D +12 more
europepmc +1 more source
EVennCorona: Annotating Protein Corona of Extracellular Vesicles by Venn Diagram
ABSTRACT Extracellular vesicles (EVs) circulating in human blood are coated by adsorbed plasma proteins, termed the EV protein corona. The corona is an intrinsic property of EVs in vivo, forming through selective adsorption of tissue microenvironment secretome components and plasma proteins, and modulates key EV biological functions including cellular ...
Somchai Chutipongtanate
wiley +1 more source
The GPCR Connection: Linking Alzheimer's Disease and Glioblastoma. [PDF]
Caniceiro AB +4 more
europepmc +1 more source
Doxycycline attenuates breast cancer related inflammation by decreasing plasma lysophosphatidate concentrations and inhibiting NF-κB activation [PDF]
core +1 more source
Chronic Pain: Epidemiology, Pathophysiology, and Clinical Management
The multidimensional nature of chronic pain is illustrated through four interconnected domains. (Left) Epidemiology and Global Burden: Chronic pain affects approximately one in five individuals globally, contributing to a rising trend in disability‐adjusted life years (YLDs) and a significant socioeconomic impact.
Zhihao Shang +12 more
wiley +1 more source
Targeting Phosphoinositide 3-Kinase to Reduce the Progression of Ovarian Cancer Cells in a 3D Collagen Model. [PDF]
Tino AB +3 more
europepmc +1 more source

