Results 111 to 120 of about 450,617 (310)

Chemical Strategies for Multistimuli Responsive Dynamic Covalent Materials in Regenerative Medicine

Advanced Healthcare Materials, EarlyView.
Multistimuli responsive dynamic covalent materials integrate reversible chemistry with the complex chemical, mechanical, and biochemical cues of regenerative environments. This review highlights chemical strategies based on orthogonal dynamic bonds, multicomponent networks, and hierarchical architectures to regulate mechanics, degradation, and ...
Saurabh Joshi, Matthew B. Baker, Dominik Schauenburg   +2 more
wiley   +1 more source

Aloe Extracts Inhibit Skin Inflammatory Responses by Regulating NF-κB, ERK, and JNK Signaling Pathways in an LPS-Induced RAW264.7 Macrophages Model

Clinical, Cosmetic and Investigational Dermatology, 2023
Fei Wang,1– 3,* Jitao Liu,1– 3 Quan An,1– 4,* Yiming Wang,1– 3 Yang Yang,1– 3 Tong Huo,1– 3 Simin Yang,5 Ruijun Ju,5 Qianghua Quan1– 4 1Research and Development Department, Yunnan Baiyao Group Health Products Co., Ltd., Kunming, People’s Republic
Wang F, Liu J, An Q, Wang Y, Yang Y, Huo T, Yang S, Ju R, Quan Q   +8 more
doaj  

LPS-induced dynamics of iron-related parameters under normal/enriched iron diet is well reproduced/predicted by the model.

, 2017
A-Serum iron, B-Liver Iron, C-Liver hepcidin, D-Spleen iron, E-Liver BMP6, F-Liver Fpn mRNA, G-Spleen Fpn protein, H-Liver pSTAT, I-Liver pSMAD, J-Duodenum iron, K-Red blood cells iron, L-Liver Fpn protein.
Mihaela Enculescu (3626096), Maximilian Hahnel (3626093), Stefan Legewie (65841), Martina U. Muckenthaler (156534), Johannes Bode (3424313), Christoph Metzendorf (3626090), Richard Sparla (3626087)   +6 more
core   +1 more source

In Vivo Monitoring of Thrombo‐Inflammatory Biomarkers via Molecularly Imprinted Polymer‐Integrated Hydrogel Microneedles

Advanced Materials, EarlyView.
A wearable electrochemical microneedle patch integrates Prussian Blue redox transduction with molecularly imprinted polymer recognition for reagent‐free sampling and detection of thrombo‐inflammatory biomarkers in dermal interstitial fluid. The platform tracks thrombin and inflammatory cytokines with sensitive in vitro, ex vivo, and in vivo performance,
Mahmoud Ayman Saleh, Peyman GhavamiNejad, Arash Khorrami Jahromi, Sanjana Srikant, Sripadh Guptha Yedire, Fatemeh Keyvani, Roozbeh Siavash Moakhar, Sajad Shiekh, Mackenzie Graham, Joe Quadrilatero, Mahla Poudineh, Sara Mahshid   +11 more
wiley   +1 more source

LPS-induced DC maturation in vivo is impaired in Inhα^-/- mice.

, 2016
Inhα+/+ and Inhα-/- 3-week-old mice were inoculated intradermal with LPS (1μg) in left ear and PBS in right ear as control. After 6, 18 and 72 h, dLN and ear epidermal layers were obtained to evaluate DC maturation. A.
Roxana Olguín-Alor (3391439), Laura C. Bonifaz (2503054), Gloria Soldevila (139753), Laura Antonio-Herrera (3391442), Eduardo A. García-Zepeda (3391448), Marisol de la Fuente-Granada (3391445)   +5 more
core   +1 more source

Ionizable Lipid‐Dependent Optimization of Steroid Lipid Nanoparticles With Tunable Immunomodulatory Properties

Advanced Materials, EarlyView.
A novel engineering strategy that establishes material design principles for incorporating anti‐inflammatory steroids into lipid nanoparticles to reduce LNP‐induced inflammation while retaining mRNA delivery. Results are validated in vitro and in three animal models of inflammation and autoimmunity in vivo.
Ajay S. Thatte, Benjamin E. Nachod, Julia Baena, Jenna Muscat‐Rivera, Lesley Chaboub, Hannah C. Safford, Hannah C. Geisler, Hannah M. Yamagata, Melgious J. Y. Ang, Michael Kegel, Alexandre Poirier, Elaine R. Tong, Zhe Zhong, Qiangqiang Shi, Jinjin Wang, Elisa Battistini, Ye Zeng, Alex G. Hamilton, Kelsey L. Swingle, Drew Weissman, Jilian R. Melamed, Michael J. Mitchell   +21 more
wiley   +1 more source

HyPLANT100: Industrialization from Assembly to the Construction Site for Gigawatt Electrolysis

Hydrogen
The global push for sustainable energy has heightened the demand for green hydrogen, which is crucial for decarbonizing heavy industry. However, current electrolysis plant capacities are insufficient.
Lukas Büsch, Malte Jakschik, Daniel Syniawa, Christian Masuhr, Lukas Christ, Jan Schachtsiek, Kay Haalck, Leon Nerlich, Elisabeth Frömsdorf, Nadine Schirmack, Benedikt Ebert, Chaman Kirty, Patrick Adler, Thorsten Schüppstuhl, Bernd Kuhlenkötter   +14 more
doaj   +1 more source

Metal–Organic Framework‐Preserved Thermostable Microneedle Patch for Minimally Invasive Detection and Monitoring of Kidney Dysfunction

Advanced Materials, EarlyView.
By growing a conformal ZIF‐8 protective layer directly on antibody‐functionalized microneedles, this work converts a fragile biosensing interface into a thermostable diagnostic platform. The MOF@MN patch enables minimally invasive NGAL detection from dermal ISF while supporting cold‐chain‐independent storage and transport for decentralized kidney ...
Yixuan Wang, Ying Liu, Avishek Debnath, Chuang Li, Zheyu Wang, Gayathri Kondepati, Saketh Balmoori, Jeremiah J. Morrissey, Ying Maggie Chen, Limei Tian, Srikanth Singamaneni   +10 more
wiley   +1 more source

PSYNDEX Tests Review für LPS-2 - Leistungsprüfsystem 2

, 2014
This is a PSYNDEX Tests Review of LPS-2 - Leistungsprüfsystem 2. PSYNDEX Tests Reviews are written in German and describe and evaluate psychological and educational tests used in the German-speaking countries.
List, Sarah
core   +1 more source

Anisotropic Masked Mycobacterium Potentiates Amplified Antitumor Trained Immunity via Spleen Targeting and Myelopoiesis Conversion

Advanced Materials, EarlyView.
An engineered Trojan Mycobacterium, developed via a “peeling‐off and masking‐up” strategy, functions as a powerful splenic myelopoiesis converter. This spleen‐targeted nanomedicine induces trained immunity to reprogram immunosuppressive myeloid reservoirs into antitumoral effectors.
Jin‐Ho Choi, Sang Nam Lee, Jang Hun Heo, Soyoung Park, Sei Hyun Park, Yong Taik Lim   +5 more
wiley   +1 more source