Results 81 to 90 of about 450,617 (310)

Minocycline attenuates lipopolysaccharide (LPS)-induced neuroinflammation, sickness behavior, and anhedonia-6

open access: yes, 2011
Day mice were challenged with saline or LPS i.p. and A) MHC II, B) TLR2, C) IL-1β, D) IL-6, and E) IDO mRNA levels were determined from hippocampus collected 4 h later. Bars represent the mean ± SEM (n = 8).
Angela Wynne (96300)   +7 more
core   +1 more source

Macrophages exposed continuously to lipopolysaccharide and other agonists that act via toll-like receptors exhibit a sustained and additive activation state [PDF]

open access: yes, 2001
Background: Macrophages sense microorganisms through activation of members of the Toll-like receptor family, which initiate signals linked to transcription of many inflammation associated genes.
Aderem, A   +17 more
core   +1 more source

Fusogenic RNA Nanomodules for Fusion‐Mediated and Multiplexed siRNA Delivery

open access: yesAdvanced Functional Materials, EarlyView.
A fusogenic lipid‐layered RNA nanomodules (L‐CRAMs) enable high‐capacity and long‐lasting siRNA delivery through membrane fusion. These nanomodules carry exceptionally large siRNA payloads, avoid conventional endosomal uptake, and release multiple functional siRNAs through Dicer‐mediated processing.
Sunghyun Moon   +5 more
wiley   +1 more source

Nanoconfinement‐Induced Second‐Harmonic Circular Dichroism via Chirality–Ferroelectric Coupling

open access: yesAdvanced Functional Materials, EarlyView.
Nanoconfinement of a ferroelectric nematic liquid crystal within a chiral nanoporous sponge yields an enhanced second‐harmonic generation circular dichroism (|gSHG–CD| ≈ 1.1). Polarization‐resolved analysis suggests an additional magnetic‐dipole‐associated nonlinear contribution under nanoconfinement, highlighting chirality–ferroelectric coupling as a ...
Jae‐Jin Lee   +5 more
wiley   +1 more source

Ultrathin (60 μm), ultralong (≥40 mm) sirolimus-eluting stent: study of clinical and safety profiles among real-world patients

open access: yesAnatolian Journal of Cardiology, 2021
Santosh Kumar Sinha   +5 more
doaj   +1 more source

LPS-induced NF-κB is inactivated by Glrx knockdown via TRAF6–IKKβ inactivation.

open access: yes, 2019
(A) LPS (100 μg/ml)-induced phosphorylation of IKKβ (15 min, 30 min) was attenuated in RAW267.4 cells treated with siGlrx. The representative Western blot and densitometry analysis from 4 independent experiments are shown. *pB) Western blotting show that
Beatriz Ferran (6264209)   +6 more
core   +1 more source

A Holistic Platform Approach for Developing Robust Pulmonary mRNA Delivery: Integrating Novel Phenolic Acid‐Derived Ionizable Lipids and Device Engineering

open access: yesAdvanced Functional Materials, EarlyView.
An integrated pulmonary mRNA delivery platform combining novel biodegradable syringic acid‐derived ionizable lipids, design‐of‐experiments formulation optimization, and vibrating‐mesh nebulizer engineering enabled stable aerosolization and efficient lung delivery.
Neha Kaushal   +21 more
wiley   +1 more source

Modulation of Inflammatory Responses by Green and Black Tea in LPS-induced RAW 264.7 Cells

open access: yes, 2010
Recently, the World Health Organization estimated that chronic diseases are responsible for 46% of disease occurrence and 59% of all deaths worldwide. Growing evidence suggests that increasing chronic disease incidence is dependent upon several factors,
Summers, Caroline Rueda
core  

yutamezy0/LPS-detector: v1.0.0

open access: yes
<p><strong>LPS-Detector</strong></p> <p>A CNN-based automatic detection model for Later Phase in S coda (LPS), which was observed at near-source stations of earthquakes occurring in the upper crust.  </p> <p>
yutamezy0
core   +1 more source

Leptin fails to blunt the lipopolysaccharide-induced activation of the hypothalamic-pituitary-adrenal axis in rats [PDF]

open access: yes, 2014
Copyright @ 2013 The authors. This work is licensed under a Creative Commons Attribution 3.0 Unported License.Obesity is a risk factor for sepsis morbidity and mortality, whereas the hypothalamic-pituitary-adrenal (HPA) axis plays a protective role in ...
Bloom, SR   +5 more
core   +1 more source

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