Results 31 to 40 of about 9,434 (185)

Freeze-Dried Lopinavir-Loaded Nanostructured Lipid Carriers for Enhanced Cellular Uptake and Bioavailability: Statistical Optimization, in Vitro and in Vivo Evaluations

Pharmaceutics, 2019
Nanostructured lipid carriers (NLCs) loaded with lopinavir (LPV) were prepared by the high-shear homogenization method. The LPV-NLCs formulations were freeze-dried using trehalose as a cryoprotectant.
Arshad Ali Khan, Jahanzeb Mudassir, Safia Akhtar, Vikneswaran Murugaiyah, Yusrida Darwis   +4 more
doaj   +1 more source

Robust Controller Designing for an Air-Breathing Hypersonic Vehicle with an HOSVD-Based LPV Model

International Journal of Aerospace Engineering, 2021
This paper focuses on the linear parameter varying (LPV) modeling and controller design for a flexible air-breathing hypersonic vehicle (AHV). Firstly, by selecting the measurable altitude and velocity as gain-scheduled variables, the original ...
Xing He, Wei Jiang, Caisheng Jiang
doaj   +1 more source

Localized Provoked Vulvodynia-An Ignored Vulvar Pain Syndrome

Frontiers in Cellular and Infection Microbiology, 2021
Localized provoked vulvodynia (LPV) causes dyspareunia among reproductive aged women. We review the pathogenesis of LPV and suggest that LPV is an inflammatory pain syndrome of the vestibular mucosa triggered by microbial antigens in a susceptible host ...
Jorma Paavonen, David A. Eschenbach
doaj   +1 more source

Acquired HIV-1 Protease Conformational Flexibility Associated with Lopinavir Failure May Shape the Outcome of Darunavir Therapy after Antiretroviral Therapy Switch

Biomolecules, 2021
Understanding the underlying molecular interaction during a therapy switch from lopinavir (LPV) to darunavir (DRV) is essential to achieve long-term virological suppression.
Simeon Eche, Ajit Kumar, Nelson Sonela, Michelle L. Gordon   +3 more
doaj   +1 more source

Virological efficacy in cerebrospinal fluid and neurocognitive status in patients with long-term monotherapy based on lopinavir/ritonavir: an exploratory study.

PLoS ONE, 2013
BackgroundData on suppression of HIV replication in the CNS and on the subsequent risk of neurocognitive impairment using monotherapy with boosted protease inhibitors are limited.MethodsOurs was an exploratory cross-sectional study in patients on ...
José R Santos, José A Muñoz-Moreno, José Moltó, Anna Prats, Adrià Curran, Pere Domingo, Josep M Llibre, Daniel R McClernon, Isabel Bravo, Jaume Canet, Victoria Watson, David Back, Bonaventura Clotet   +12 more
doaj   +1 more source

Initiation of a Lung Protective Ventilation Strategy in the Emergency Department: Does an Emergency Department-Based ICU Make a Difference?

Critical Care Explorations, 2022
BACKGROUND:. Lung protective ventilation (LPV) is a key component in the management of acute respiratory distress syndrome and other acute respiratory pathology.
Carrie E. Harvey, MD, Nathan L. Haas, MD, Chiu-Mei Chen, MS, MA, James A. Cranford, PhD, Joseph A. Hamera, MD, Renee A. Havey, RN, Ryan E. Tsuchida, MD, Benjamin S. Bassin, MD   +7 more
doaj   +1 more source

Optimal Shape and Boil-Off Gas Generation of Fuel Tank for LNG Fueled Tugboat

한국해양공학회지, 2020
This paper proposes the optimal shape of an LNG fuel tank with a lattice pressure vessel (LPV) design for a tugboat. The LPV is a Type C tank with a design philosophy of “design by analysis,” which facilitates greater variability of shape compared with ...
Jung-Woog Kim, Jin-yeong Jeong, Dae-Jun Chang   +2 more
doaj   +1 more source

Comparison of antiviral effect for mild-to-moderate COVID-19 cases between lopinavir/ritonavir versus hydroxychloroquine: A nationwide propensity score-matched cohort study

International Journal of Infectious Diseases, 2021
Objectives: We aimed to compare the antiviral effect of hydroxychloroquine (HCQ) and lopinavir/ritonavir (LPV/r) in patients with COVID-19. Methods: Nationwide retrospective case-control study was conducted to compare the effect of HCQ and LPV/r on viral
Min Joo Choi, Minsun Kang, So Youn Shin, Ji Yun Noh, Hee Jin Cheong, Woo Joo Kim, Jaehun Jung, Joon Young Song   +7 more
doaj   +1 more source

Drought Exposure and Dynamic Input Adjustment in North Central U.S. Agriculture

Agribusiness, EarlyView.
ABSTRACT This article examines whether realized extreme drought episodes affect the speed of adjustment of derived input demands and output supplies toward their long‐run equilibrium in U.S. agriculture, focusing on states in the North Central Region.
Victor H. Lana Pinto, Lilyan E. Fulginiti, Richard K. Perrin   +2 more
wiley   +1 more source

The Bochum Survey of the Southern Galactic Disk: IV. Multi‐Band Photometry

Astronomische Nachrichten, EarlyView.
ABSTRACT The Southern Galactic Disk Survey (GDS) monitored a mosaic of 268 fields along a 6°‐wide stripe in the southern galactic disk from September 2010 to September 2019. These fields were observed between 21 and 407 times sim r′$$ {r}^{\prime } $$ultaneously in (8mag≲r′≲18mag$$ 8\kern0.6em \mathrm{mag}\lesssim {r}^{\prime}\lesssim 18\kern0.6em ...
Julia Blex, Dominik J. Bomans, Kerstin Weis, Markus Demleitner, Moritz Hackstein, Anna Franckowiak, Michael Ramolla, Christian Westhues, Christofer Fein, Rolf Chini   +9 more
wiley   +1 more source