Results 41 to 50 of about 9,434 (185)
British Journal of Clinical Pharmacology, EarlyView.Abstract Background We conducted a systematic review of clinical trials and cohort studies on HIV post‐exposure prophylaxis (PEP) regimens to inform updated 2025 Canadian guidelines. Methods We searched Medline and Embase (July 2017–June 2024) for studies reporting on: HIV acquisition, PEP completion, adverse events (AEs) leading to discontinuation and/
Stanley O. Onyegbule +12 more
wiley +1 more source
LPV Control for the Full Region Operation of a Wind Turbine Integrated with Synchronous Generator
The Scientific World Journal, 2015 Wind turbine conversion systems require feedback control to achieve reliable wind turbine operation and stable current supply. A robust linear parameter varying (LPV) controller is proposed to reduce the structural loads and improve the power extraction ...
Guoyan Cao +2 more
doaj +1 more source
Performance change detection and recovery in inferential control loops
The Canadian Journal of Chemical Engineering, EarlyView.Abstract In most industrial environments, soft sensors are crucial for estimating variables that are hard to measure. It is critical that these variables be estimated quickly and accurately because they are closely linked to plant safety and profit. Therefore, performance drift in the soft sensors cannot be ignored.
Xuanhui Zhai, Yuri A. W. Shardt
wiley +1 more source
Epilepsia, EarlyView.Abstract Objective RAP‐219, a potent selective negative allosteric modulator (NAM) of α‐amino‐3‐hydroxy‐5‐methyl‐4‐isoxazolepropionic acid receptor (AMPAR) associated with γ8 transmembrane AMPAR regulatory protein (TARPγ8), is in phase 3 development for refractory focal epilepsy. This study was undertaken to assess efficacy and motor function following
Jose A. Matta +5 more
wiley +1 more source
Energy Science &Engineering, EarlyView.Deployment of an aging‐based controller during designing of optimal lithium‐ion battery—supercapacitor (LB‐Sc) hybrid energy storage system (HESS) capacity, in off‐grid IREMGs, improves performance of the LB and reduces its aging rate. Also, annualised cost of the LB‐Sc HESS improves by 33.15% in relation to optimal LB SESS.
Isaac Gwayi +2 more
wiley +1 more source
Amino Acid Prodrugs: An Approach to Improve the Absorption of HIV-1 Protease Inhibitor, Lopinavir
Pharmaceuticals, 2014 Poor systemic concentrations of lopinavir (LPV) following oral administration occur due to high cellular efflux by P-glycoprotein (P-gp) and multidrug resistance-associated proteins (MRPs) and extensive metabolism by CYP3A4 enzymes.
Mitesh Patel +4 more
doaj +1 more source
IFT-LPV: Data-Based Tuning of Fixed Structure Controllers for LPV Systems
IFAC-PapersOnLine, 2015 Fixed structure controllers are widely used, however the tuning thereof can be cumbersome and gives no guarantee of optimality, especially when the system is Linear Parameter-Varying (LPV). Iterative Feedback Tuning (IFT) is a technique for the optimisation of a parameterised controller based on closed-loop experiments.
Navalkar, S.T. +2 more
openaire +2 more sources
BMC Anesthesiology, 2018 Background The benefits of lung-protective ventilation (LPV) with a low tidal volume (6 mL/kg of ideal body weight [IBW]), limited plateau pressure (
Seung Hyun Kim +4 more
doaj +1 more source
Lung-protective ventilation worsens ventilator-induced diaphragm atrophy and weakness
Respiratory Research, 2020 Background Lung–protective ventilation (LPV) has been found to minimize the risk of ventilator–induced lung injury (VILI). However, whether LPV is able to diminish ventilator–induced diaphragm dysfunction (VIDD) remains unknown.
Xian-Long Zhou +4 more
doaj +1 more source
Sliding Mode Control in Aerospace Applications: A Survey
International Journal of Robust and Nonlinear Control, EarlyView.ABSTRACT Sliding mode control (SMC) enjoys robustness to matched and unmatched (in the case of minimum phase input‐output dynamics) bounded perturbations, and finite time convergence. Second‐order and higher‐order sliding mode control systems (2‐SMC/HOSMC) retain all the advantages of sliding mode control, but in addition can be applied to systems of ...
Yuri Shtessel, Christopher Edwards
wiley +1 more source