Results 61 to 70 of about 9,434 (185)

Efficacy and Safety of Lopinavir/Ritonavir for Treatment of COVID-19: A Systematic Review and Meta-Analysis

Tropical Medicine and Infectious Disease, 2020
(Background) Lopinavir-ritonavir (LPV/RTV) is a human immunodeficiency virus (HIV) antiviral combination that has been considered for the treatment of COVID-19 disease.
Saad Alhumaid, Abbas Al Mutair, Zainab Al Alawi, Naif Alhmeed, Abdul Rehman Zia Zaidi, Mansour Tobaiqy   +5 more
doaj   +1 more source

Linear Parameter Varying Versus Linear Time Invariant Reduced Order Controller Design of Turboprop Aircraft Dynamics [PDF]

ITB Journal of Engineering Science, 2012
The applicability of parameter varying reduced order controllers to aircraft model is proposed. The generalization of the balanced singular perturbation method of linear time invariant (LTI) system is used to reduce the order of linear parameter varying (
Widowati, Bambang Riyanto, Hari Muhammad
doaj   +1 more source

HIV viral suppression in children and adolescents who transitioned from ritonavir‐boosted lopinavir‐ to dolutegravir‐based antiretroviral therapy in Lesotho

HIV Medicine, EarlyView.
Abstract Objectives Children and adolescents living with HIV previously taking ritonavir‐boosted lopinavir (LPV/r)‐based antiretroviral therapy (ART) have been programmatically transitioned to dolutegravir (DTG)‐based regimens in many country programs.
Jacob Blankenberger, Teresa L. F. Steffy, Tristan Lee, Thithili Makhesi, Meenakshi Bakaya, Akash Devendra, Pheello Mothepu, Lipontso Motaboli, Nadine Tschumi, Anna Klicpera, Tapiwa Tarumbiswa, Frédérique Chammartin, Lineo K. Thahane, Niklaus D. Labhardt, Jennifer A. Brown   +14 more
wiley   +1 more source

Confirmation of the presence of non‐native, self‐sustaining brook trout Salvelinus fontinalis and genomic distinction between populations in southwest Germany

Journal of Fish Biology, EarlyView.
Abstract Introduced to Europe from North America in the 19th century, Brook trout, Salvelinus fontinalis, can negatively impact native fish communities, yet self‐sustaining populations remain rare in southern Germany despite a long stocking history. Here, we report a survey of 1618 electrofishing records from Baden‐Württemberg, identifying only three ...
J. Peter Koene, Jan Baer, Patrick Bartolin, Arne Jacobs, David Frei, Albert Ros, Pascal Vonlanthen, Alexander Brinker   +7 more
wiley   +1 more source

Surrogate‐Assisted Nonlinear Model Predictive Control for a Lambda Robot

Proceedings in Applied Mathematics and Mechanics, Volume 26, Issue 4, December 2026.
ABSTRACT This work presents a nonlinear model predictive control (NMPC) framework for a lambda‐shaped parallel robot that incorporates data‐driven surrogates to facilitate control design. An inverse surrogate model is used to provide an efficient initialization of the control inputs for NMPC.
Sanam Hajipour, Tianyu Zhai, Dieter Bestle   +2 more
wiley   +1 more source

LPV Updates for Sequentially Linearized Moving Horizon Estimation of Nonlinear Systems

Proceedings in Applied Mathematics and Mechanics, Volume 26, Issue 4, December 2026.
ABSTRACT Moving horizon estimation (MHE) provides high‐precision state estimation for nonlinear systems, but it is often limited by the substantial computational demands of solving a nonlinear optimization problem at every sampling step. To address this issue, we develop an efficient MHE scheme based on linear parameter‐varying (LPV) formulation, where
Jiaxin Ji, Jan Heiland, Dimitrios S. Karachalios, Hossam S. Abbas   +3 more
wiley   +1 more source

Bayesian optimized color filter: A fast method for segmentation of plant phenotypes from 3D point cloud images

The Plant Phenome Journal, Volume 9, Issue 1, December 2026.
Abstract Multispectral three‐dimensional (3D) imaging offers substantial potential for plant phenotyping, yet manual segmentation of plant organs remains a bottleneck in breeding programs. We developed a color‐based filtering workflow for faba bean (Vicia faba L.) point clouds that optimizes lower and upper thresholds of spectral indices and broadband ...
Lennart Scheer, Benjamin Wittkop, Andreas Stahl, Olaf Sass, Gregor Welna, Hanna Tietgen, Rod J. Snowdon   +6 more
wiley   +1 more source

Reduced reproductive potential in young healthy women with hereditary breast and/or ovarian cancer syndrome

Communications Medicine
Background Young, healthy women carrying a pathogenic or likely pathogenic variant (P/LPV) in genes configuring the hereditary breast and/or ovarian cancer (HBOC) syndrome face several non-oncological issues.
Giovanna Sighinolfi, Giovanni Grandi, Elena Barbieri, Marta Venturelli, Claudia Piombino, Chiara Melotti, Rebecca Lippi Bruni, Riccardo Costantini Cuoghi, Roberto D’Amico, Matteo Lambertini, Fedro A. Peccatori, Elena Tenedini, Massimo Dominici, Laura Cortesi, Antonio La Marca, Angela Toss   +15 more
doaj   +1 more source

Deep Contrastive Learning for High‐Throughput Prediction of Drug Resistance Mutations from Sequences

Advanced Science, Volume 13, Issue 59, 23 October 2026.
This study presents DeepMutDTA, a deep learning framework aimed at predicting mutation‐induced changes in protein‐drug interactions and prioritizing variants potentially linked to drug resistance. Trained on large‐scale data, it incorporates SimSiam‐MuTF, a label‐aware contrastive fine‐tuning strategy that encourages separation between WT and MT ...
Xiaowen Hu, Pan Zhang, Shangqian Wu, Hao Sun, Minwei Li, Sophia Tsoka, Zizhang Sheng, Lei Deng   +7 more
wiley   +1 more source

Quality improvement project to improve adherence to lung protective ventilation guidelines

BMJ Open Quality
Introduction Lung protective ventilation (LPV) is advocated for all patients requiring mechanical ventilation (MV), for any duration of time, to prevent worsening lung injury. Previous studies proved simple interventions can increase awareness of LPV and
Dhruv Parekh, Adam Harriman, Katrina Butler, Jonathan Weblin   +3 more
doaj   +1 more source