Voice and Speech in Atypical Parkinsonian Disorders
Background Motor speech disorders are early, common, and functionally limiting features of atypical parkinsonian disorders (APDs) such as progressive supranuclear palsy (PSP), corticobasal syndrome (CBS), and multiple system atrophy (MSA). These impairments are underrecognized and undertreated in neurology clinics.
Federico Rodriguez‐Porcel +48 more
wiley +1 more source
Clinical impact of double protease inhibitor boosting with Lopinavir/Ritonavir and Amprenavir as part of salvage antiretroviral therapy [PDF]
Purpose: Double protease inhibitor (PI) boosting is being explored as a new strategy in salvage antiretroviral (ARV) therapy. However, if a negative drug interaction leads to decreased drug levels of either or both PIs, double PI boosting could lead to ...
Gough, K. +10 more
core
CSF LPV concentrations and viral load in viral suppressed patients on LPV/r monotherapy given once daily [PDF]
Introduction: Plasma trough concentrations of lopinavir (LPV) given as LPV/r 800/200 mg once daily (OD) are reduced in comparison with 400/100 mg twice daily (BID). While OD dosage of LPV/r is sufficient to achieve viral suppression in plasma, data about
Masó Serra, Margarita +8 more
core +1 more source
Quality improvement project to improve adherence to lung protective ventilation guidelines
Introduction Lung protective ventilation (LPV) is advocated for all patients requiring mechanical ventilation (MV), for any duration of time, to prevent worsening lung injury. Previous studies proved simple interventions can increase awareness of LPV and
Dhruv Parekh +3 more
doaj +1 more source
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski +9 more
wiley +1 more source
Two-Degree-of-Freedom Controller Design for Linear Parameter-Varying Systems [PDF]
A design strategy for Linear Parameter-Varying (LPV) systems is considered in a Two-Degree-Of-Freedom (TDOF) control framework. First, a coprime factorization for LPV systems is introduced.
Wei, Xie, Eisaka, Toshio
core +1 more source
Flexible-Link Robot Control Using a Linear Parameter Varying Systems Methodology
This paper addresses the issues of the Linear Parameter Varying (LPV) modelling and control of flexible-link robot manipulators. The LPV formalism allows the synthesis of nonlinear control laws and the assessment of their closed-loop stability and ...
Houssem Halalchi +2 more
doaj +1 more source
Robust model predictive control based on polytopic LPV model for hypersonic vehicles
Considering the air-breathing hypersonic vehicle (AHV) system with strong nonlinearity and external disturbance, an off-line robust model predictive controller (RMPC) is presented based on the polytopic LPV model under the effects of disturbances ...
Shaokang Zhang +7 more
core +1 more source
LPV-MPC control of autonomous vehicles [PDF]
In this work, a novel approach is presented to solve the trajectory tracking problem for autonomous vehicles. This method is based on the use of a cascade control where the external loop solves the position control using a novel Linear Parameter Varying -
Puig Cayuela, Vicenç +2 more
core +1 more source
ICU Implementation Determinants and Delivery of Lung Protective VentilationTake-Home Points
Background: Lung protective ventilation (LPV) improves mortality in patients with ARDS and is applied widely in other patients receiving mechanical ventilation. Despite strong evidence, LPV is implemented inconsistently.
Chad H. Hochberg, MD, MHS +7 more
doaj +1 more source

