Results 91 to 100 of about 53,833 (282)

Rhoifolin Alleviates Ulcerative Colitis by Targeting NMNAT1 and Activating SIRT1‐FOXO1 Signaling to Enhance ILC3s Effector Function

Advanced Science, EarlyView.
Rhoifolin directly targets NMNAT1, thereby activating nicotinamide salvage pathway and promoting intracellular NAD+ biosynthesis. Elevated NAD+ levels enhance SIRT1 activity, leading to FOXO1 deacetylation and nuclear translocation. Nuclear FOXO1 subsequently binds to the IL‐22 promoter, upregulating IL‐22 transcription and potentiating ILC3 effector ...
Hongqiong Yang, Yishu Zhang, Sijia Feng, Xiaoqing Ma, Jiayi Feng, Junwei Wang, Jialin Gao, An Pan, Dapeng Wu, Kang Ding, Caijuan Zheng, Qi Lv, Lihong Hu   +12 more
wiley   +1 more source

On The Least Number of Palindromes in an Infinite Word

, 2012
We investigate the least number of palindromic factors in an infinite word. We first consider general alphabets, and give answers to this problem for periodic and non-periodic words, closed or not under reversal of factors.
Zamboni, LQ, FICI, Gabriele
core  

Long Noncoding RNA PCALRx Interacts with Pyruvate Carboxylase to Drive Multi‐Organ Developmental Toxicity in Zebrafish Embryos Exposed to Amoxicillin

Advanced Science, EarlyView.
Embryonic amoxicillin exposure disrupts multi‐organ development in zebrafish larvae through a lncRNA–metabolic enzyme regulatory axis. PCALRx associates with pyruvate carboxylase, promotes PC protein ubiquitination, and impairs mitochondrial energy metabolism, while vitamin B1 partially restores PC‐centered metabolic function and developmental outcomes.
Yixue Yao, Ping Jiang, Xinli Zhou, Mengying Yin, Qiong Luo, Hui Wang   +5 more
wiley   +1 more source

Life quality and institutionalized elderly’s functional capacity

Kairós Gerontologia, 2015
Objective: Analyzing the life quality (LQ) and the institutionalized elderly’s functional capacity (FC). Materials and Methods: It was consisted an example of 20 elderly, institutionalized, and it was verified the LQ and the FC.
Julia Roberta de Oliveira, Paulo Roberto Rocha Júnior   +1 more
doaj  

Limitations and Benefits of Link Quality Prediction in Stochastic Wireless Multihop Networks

International Journal of Distributed Sensor Networks
In wireless multihop networks, such as wireless sensor networks, link quality (LQ) is one of the most important metrics and is widely used in higher-layer applications such as routing protocols.
Xiaofei Shi, Wenxing Liao, Zhenhua Hu
doaj   +1 more source

Liquiritin Protects Against Cardiac Fibrosis After Myocardial Infarction by Inhibiting CCL5 Expression and the NF-κB Signaling Pathway

Drug Design, Development and Therapy, 2022
Xue Han,1,* Yakun Yang,1,* Muqing Zhang,2,3 Li Li,4 Yucong Xue,2 Qingzhong Jia,4 Xiangting Wang,2,5 Shengjiang Guan3,6 1School of Pharmacy, Hebei University of Chinese Medicine, Shijiazhuang, People’s Republic of China; 2College of Integrative ...
Han X, Yang Y, Zhang M, Li L, Xue Y, Jia Q, Wang X, Guan S   +7 more
doaj  

AARS1‐Mediated RUNX3 K193 Lactylation Enhances the Activation and Cytotoxicity of CD8+T Cells in Smoking‐Related Emphysema

Advanced Science, EarlyView.
Exposure to CS causes an elevation of AARS1 levels, which increases the levels of RUNX3 lactylation at the K193 site and increases protein levels of RUNX3 through inhibition of autolysosomal degradation. Elevated RUNX3 levels promote CD8+T cell activation and augment their cytotoxicity, which induces alveolar epithelial cell death and facilitates the ...
Ying Zhu, Jiaheng Lin, Yifan Li, Qiaoqiao Zhou, Min Yu, Cheng Cheng, Kang Chang, Dang Lin, Tao Bian, Yan Wu, Lu Lu, Haibo Xia, Qizhan Liu   +12 more
wiley   +1 more source

Perbandingan Risiko Dan Return Investasi Pada Indeks Lq 45 Dengan Indeks Jakarta Islamic Index (JII)

El-Jizya: Jurnal Ekonomi Islam, 2018
This study compares the risks and returns between the two indices in the Indonesian Stock Exchange (IDX), namely the LQ 45 Index and the Jakarta Islamic Index (JII). This research period, starting from January 2008 to December 2017.
Yoyok Prasetyo
doaj   +1 more source

One‐Pot Direct Recycling of Spent LiCoO2 via Synergistic Binder Defluorination and Phase Reconstruction

Advanced Science, EarlyView.
A Li+‐DES system enables targeted defluorination and synergistic repair of spent LiCoO2 cathodes in a single medium. The regenerated material recovers a well‐ordered layered structure with a high capacity of 157.4 mAh g−1 and 83.1% capacity retention after 300 cycles, demonstrating a sustainable and efficient closed‐loop recycling strategy for lithium ...
Yingjie Hu, Songhu Ye, Fan Li, Chunhui Zhong, Bailin Xiang, Yulan Chen, Lili Zhi, Qingxia Liu, Junfeng Li, Zhixiang Chen   +9 more
wiley   +1 more source

Repurposing a Small Molecule Plant Hormone as a Tunable ON‐Switch for CAR‐T Cell Immunotherapy

Advanced Science, EarlyView.
By engineering a receptor system integrating the plant auxin receptor AFB1 with its co‐receptor IAA7, we enable ligand‐dependent interactions triggered by the plant hormone auxins. This design allows rapid, reversible, and dose‐dependent T cell activation, resulting in potent cytotoxicity against B‐cell lymphoma in vitro and in vivo.
Hongxiang Zeng, Lei Zheng, Rongkun Tao, Sirui Zheng, Yanke Zhong, Yongxia Niu, Peng Zhang, Xiang Ma, Chen Yang, Min Zhang, Fuyu Duan, Jing Yang, Xuan Wei, Xiang Zhou, Zhenbiao Yang, Zhaoxi Sun, Qizhou Lian   +16 more
wiley   +1 more source