Results 41 to 50 of about 18,853 (204)

Evolution of Nuclear Shell Structure due to the Pion Exchange Potential

, 2006
The evolution of nuclear shell structure is investigated for the first time within density-dependent relativistic Hartree-Fock theory and the role of $\pi$-exchange potential is studied in detail.
Blatt J. M., Geng L.-S., Hiroyuki Sagawa, Jie Meng, Long W. H., Long W. H. Giai N. V. Meng J., Nguyen Van Giai, Reinhard P.-G., Serot B., WenHui Long, Yukawa H.   +10 more
core   +3 more sources

Enhancing theranostic potential of anti-mesothelin sdAb through site-specific labeling at a unique conserved lysine by molecular engineering

EJNMMI Radiopharmacy and Chemistry
Background Mesothelin is a 40 kDa glycoprotein overexpressed in several cancers, including triple-negative breast cancer (TNBC). The anti-mesothelin single-domain antibody (sdAb, or nanobody) A1 can serve as a radio-theranostic agent, but random DOTA ...
Émilien N’Guessan, Florian Raes, Mitra Ahmadi, Sandrine Bacot, Laurent Dumas, Julien Leenhardt, Marlène Debiossat, Clémence André, Jean-Luc Lenormand, Catherine Ghezzi, Daniel Fagret, Charlotte Lombardi, Alexis Broisat   +12 more
doaj   +1 more source

Antiproliferative activity, cell-cycle arrest, apoptotic induction and LC-HRMS/MS analyses of extracts from two Linum species

Pharmaceutical Biology, 2022
Context Linum is the largest genus of the Linaceae family; the species of this genus are known to have anticancer activity.Objective In this study, ethyl acetate extracts of L. numidicum Murb. (EAELN) and L. trigynum L.
Ryma Mouna, Alexis Broisat, Abdalwahab Ahmed, Marlène Debiossat, Ahcène Boumendjel, Catherine Ghezzi, Zahia Kabouche   +6 more
doaj   +1 more source

PACS-Herschel FIR detections of Lyman-alpha emitters at 2.0

, 2012
In this work we analyze the physical properties of a sample of 56 spectroscopically selected star-forming (SF) Ly$\alpha$ emitting galaxies at 2.0$\lesssim$z$\lesssim$3.5 using both a spectral energy distribution (SED) fitting procedure from rest-frame ...
A. Bongiovanni, A. Cimatti, A. Ederoclite, A. M. Pérez García, A. Poglitsch, B. Altieri, B. Magnelli, Balestra, Blanc, Bond, Bongiovanni, Bruzual, Buat, Calzetti, Chapman, Chary, Cowie, Cowie, Cowie, D. Elbaz, D. Lutz, Deharveng, E. Daddi, E. Sturm, Elbaz, Elbaz, Elmegreen, F. Pozzi, Feldmann, Finkelstein, Finkelstein, Finkelstein, Finkelstein, Gawiser, Gawiser, Grazian, Gronwall, Guaita, Guaita, H. Aussel, Hogg, Hopkins, Hopkins, I. Oteo, I. Pintos-Castro, I. Valtchanov, J. Cepa, Kennicutt, Kornei, L. Tacconi, Lai, Le Floc’h, Lutz, M. Sánchez-Portal, Madau, Murayama, N. Förster Schreiber, Neufeld, Nilsson, Nilsson, Nilsson, Nilsson, Nordon, Oke, Ono, Oteo, Ouchi, Ouchi, P. Andreani, P. Popesso, Peng, Pentericci, Pentericci, Pilbratt, Pirzkal, Poglitsch, Popesso, Pérez-González, R. Genzel, R. Maiolino, R. Pérez-Martínez, Reddy, Rhoads, S. Berta, Salpeter, Santini, Shioya, Wuyts   +87 more
core   +1 more source

Dual Action of Dipyridamole in Experimental Rheumatoid Arthritis: Suppression of Joint Inflammation and Upregulation of Muscle Anabolism via Adenosine and AMPK pathways

Arthritis &Rheumatology, Accepted Article.
Introduction Rheumatoid sarcopenia, characterized by the progressive loss of skeletal muscle mass and function, is a frequent comorbidity in rheumatoid arthritis (RA), linked to prolonged, severe systemic inflammation. Purinergic signaling (adenosine, AMP, and ATP) plays a crucial role in inflammation, myogenesis, and muscle hypertrophy.
Miguel Marco‐Bonilla, Maria Fresnadillo, Irene Sanchez‐Platero, Macarena de la Riva‐Bueno, Fernando Huete‐Toral, Gonzalo Carracedo, Carmen Conde, Yolanda Benitez, Pablo Minguez, Sandra Carolina Cifuentes, Joaquin Rams, Gabriel Herrero‐Beaumont, Raquel Largo, Aránzazu Mediero   +13 more
wiley   +1 more source

Side by side comparison of NOTA and DOTA for conjugation efficiency, gallium-68 labeling, and in vivo biodistribution of anti-mesothelin sdAb A1-His

EJNMMI Radiopharmacy and Chemistry
Background Mesothelin is a glycoprotein overexpressed in various cancers, with limited expression in healthy tissues. The single-domain antibody (sdAb, or nanobody) A1-His has previously successfully been validated in mice for the SPECT imaging of ...
Émilien N’Guessan, Sandrine Bacot, Florian Raes, Julien Leenhardt, Thibault Guenard, Laurent Dumas, Catherine Ghezzi, Daniel Fagret, Charlotte Lombardi, Alexis Broisat, Mitra Ahmadi   +10 more
doaj   +1 more source

Impact of a Moderate CYP3A4 Inducer (Bosentan) on Lurbinectedin Pharmacokinetics and Safety in Patients with Advanced Solid Tumors: An Open-Label, Two-Way, Crossover, Phase Ib Drug–Drug Interaction Study

Pharmaceuticals
This open-label, two-way, crossover, phase Ib drug–drug interaction study investigated whether the pharmacokinetics (PKs) and safety profile of lurbinectedin (LRB) are affected by co-administration of a moderate CYP3A4 inducer (bosentan, BOS) in adult ...
Irene Moreno, Tatiana Hernández, Emiliano Calvo, Salvador Fudio, Carmen Kahatt, Cristian Fernández, Jorge Luis Iglesias, Gema Corral, Laura Pérez-Ramos, Lola Montilla, Ali Zeaiter, Rubin Lubomirov   +11 more
doaj   +1 more source

Large strain nonlinear model of lead rubber bearings for beyond design basis earthquakes

Nuclear Engineering and Technology, 2019
Studies on the application of the lead rubber bearing (LRB) isolation system to nuclear power plants are being carried out as one of the measures to improve seismic performance.
Seunghyun Eem, Daegi Hahm
doaj   +1 more source

Amplification in Mechanical Properties of a Lead Rubber Bearing for Various Exposure Times to Low Temperature

Buildings, 2023
In this paper, new formulations to predict the change in mechanical properties, namely, post-yield stiffness and characteristic strength of lead rubber bearings (LRBs) at low ambient temperatures, are proposed based on test results. Proposed formulations
Cansu Yasar, Volkan Karuk, Onur Kaplan, Esengul Cavdar, Gokhan Ozdemir   +4 more
doaj   +1 more source

Spectral variability on primitive asteroids of the Themis and Beagle families: space weathering effects or parent body heterogeneity?

, 2016
Themis is an old and statistically robust asteroid family populating the outer main belt, and resulting from a catastrophic collision that took place 2.5$\pm$1.0 Gyr ago.
Barucci, M. A., Campins, H., Fornasier, S., Lantz, C., Nesvorny, D., Perna, D.   +5 more
core   +3 more sources