Results 41 to 50 of about 2,934 (189)

Antiproliferative activity, cell-cycle arrest, apoptotic induction and LC-HRMS/MS analyses of extracts from two Linum species

open access: yesPharmaceutical Biology, 2022
Context Linum is the largest genus of the Linaceae family; the species of this genus are known to have anticancer activity.Objective In this study, ethyl acetate extracts of L. numidicum Murb. (EAELN) and L. trigynum L.
Ryma Mouna   +6 more
doaj   +1 more source

Burrow Persistence and Spatial Distribution of Federally and State‐Protected Gopher Tortoise (Gopherus polyphemus) Populations in Southwest Alabama

open access: yesAnimal Conservation, EarlyView.
The gopher tortoise (Gopherus polyphemus), a keystone species and ecosystem engineer, has declined by ~80% over the past century due to primarily habitat loss. In a 28‐year resurvey of federally protected Mobile County and state‐protected Baldwin County, we found tortoise populations persisted at ~59% and ~31% of sites, respectively, with significant ...
Robin B. Lloyd Jr.   +4 more
wiley   +1 more source

A single-domain antibody for the detection of pathological Tau protein in the early stages of oligomerization

open access: yesJournal of Translational Medicine
Background Soluble oligomeric forms of Tau protein have emerged as crucial players in the propagation of Tau pathology in Alzheimer’s disease (AD). Our objective is to introduce a single-domain antibody (sdAb) named 2C5 as a novel radiotracer for the ...
Nicolas De Leiris   +13 more
doaj   +1 more source

Amplification in Mechanical Properties of a Lead Rubber Bearing for Various Exposure Times to Low Temperature

open access: yesBuildings, 2023
In this paper, new formulations to predict the change in mechanical properties, namely, post-yield stiffness and characteristic strength of lead rubber bearings (LRBs) at low ambient temperatures, are proposed based on test results. Proposed formulations
Cansu Yasar   +4 more
doaj   +1 more source

Non‐Rigid 3D Shape Correspondences: From Foundations to Open Challenges and Opportunities

open access: yesComputer Graphics Forum, EarlyView.
Abstract Estimating correspondences between deformed shape instances is a long‐standing problem in computer graphics; numerous applications, from texture transfer to statistical modelling, rely on recovering an accurate correspondence map. Many methods have thus been proposed to tackle this challenging problem from varying perspectives, depending on ...
A. Zhuravlev   +14 more
wiley   +1 more source

Allele-specific RNAi selectively silences mutant SOD1 and achieves significant therapeutic benefit in vivo

open access: yesNeurobiology of Disease, 2006
RNA interference (RNAi) has the potential to treat diseases caused by dominant, gain-of-function type of gene mutations. In these diseases, one allele is mutated and produces a toxic protein, whereas the other allele is normal and performs vital ...
Xugang Xia   +3 more
doaj   +1 more source

Establishing Shape Correspondences: A Survey

open access: yesComputer Graphics Forum, EarlyView.
Abstract Shape correspondence between surfaces in 3D is a central problem in geometry processing, concerned with establishing meaningful relations between surfaces. While all correspondence problems share this goal, specific formulations can differ significantly: Downstream applications require certain properties that correspondences must satisfy ...
A. Heuschling, H. Meinhold, L. Kobbelt
wiley   +1 more source

Large strain nonlinear model of lead rubber bearings for beyond design basis earthquakes

open access: yesNuclear Engineering and Technology, 2019
Studies on the application of the lead rubber bearing (LRB) isolation system to nuclear power plants are being carried out as one of the measures to improve seismic performance.
Seunghyun Eem, Daegi Hahm
doaj   +1 more source

Quibbling with the LRB over "Hackers"

open access: yes, 2012
In a recent piece for the LRB, Mattathias Schwartz gives an inside look at the truly scary world of carding, the practice of stealing credit card information, through a review of Mischa Glenny's new book <i> DataMarket: How Hackers Became the New Mafia </i> .
openaire   +2 more sources

Limit states for the damage assessment of bridges supported on LRB bearings

open access: yesJournal of Physics: Conference Series, 2015
There is now a common awareness that excessive strength is neither essential nor a synonymous of good performance in strong earthquakes. It is widely recognized that the design process should put more emphasis on predicting structural damage, according to the performance -based design philosophy. This paper presents an approach for assessing the damage
M Jara, C Gómez, J M Jara, B A Olmos
openaire   +1 more source

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