LRP5, SLC6A3, and SOX10 Expression in Conventional Ameloblastoma
Genes, 2023 Cell proliferation and invasion are characteristic of many tumors, including ameloblastoma, and are important features to target in possible future therapeutic applications. Objective: The objective of this study was the identification of key genes and inhibitory drugs related to the cell proliferation and invasion of ameloblastoma using bioinformatic ...
Lorena Correa-Arzate +6 more
openaire +2 more sources
Up-regulation Of Pai-1 And Down-regulation Of Upa Are Involved In Suppression Of Invasiveness And Motility Of Hepatocellular Carcinoma Cells By A Natural Compound Berberine [PDF]
, 2016 published_or_final_versio
Cao, F +9 more
core +9 more sources
The Wnt Co-Receptor Lrp5 Is Required for Cranial Neural Crest Cell Migration in Zebrafish. [PDF]
PLoS ONE, 2015 During vertebrate neurulation, cranial neural crest cells (CNCCs) undergo epithelial to mesenchymal transition (EMT), delaminate from the neural plate border, and migrate as separate streams into different cranial regions.
Bernd Willems +5 more
doaj +1 more source
WNT signalling in prostate cancer [PDF]
, 2017 Genome sequencing and gene expression analyses of prostate tumours have highlighted the potential importance of genetic and epigenetic changes observed in WNT signalling pathway components in prostate tumours-particularly in the development of castration-
A Ghoshal +166 more
core +2 more sources
The C-terminal region Mesd peptide mimics full-length Mesd and acts as an inhibitor of Wnt/β-catenin signaling in cancer cells. [PDF]
PLoS ONE, 2013 While Mesd was discovered as a specialized molecular endoplasmic reticulum chaperone for the Wnt co-receptors LRP5 and LRP6, recombinant Mesd protein is able to bind to mature LRP5 and LRP6 on the cell surface and acts as a universal antagonist of LRP5/6
Cuihong Lin +6 more
doaj +1 more source
Annals of Medicine, 2022 Objective To explore the clinical manifestations and search for the variants of six related genes (LRP5, FZD4, TSPAN12, NDP, KIF11 and ZNF408) in Chinese patients with familial exudative vitreoretinopathy (FEVR), and investigate the correlation between ...
Jianbo Mao +8 more
doaj +1 more source
Coronectomy of deeply impacted lower third molar : incidence of outcomes and complications after one year follow-up [PDF]
, 2015 Objectives: The purpose of present study was to assess the surgical management of impacted third molar with proximity to the inferior alveolar nerve and complications associated with coronectomy in a series of patients undergoing third molar surgery ...
Ajbage, Jimoh Olubanwo +6 more
core +3 more sources
Deletion of a Single beta-Catenin Allele in Osteocytes Abolishes the Bone Anabolic Response to Loading [PDF]
, 2014 The Wnt/β-catenin signaling pathway is essential for bone cell viability and function and for skeletal integrity. To determine if β-catenin in osteocytes plays a role in the bone anabolic response to mechanical loading, 18- to 24-week-old osteocyte β ...
Akhter +53 more
core +2 more sources
Polymorphism in LRP5 (rs556442) is associated with higher TG levels in Iranian children
Annals of Human Biology, 2017 Background: Wnt signalling/LRP5 is involved in adipogenesis by down-regulating adipogenic transcription factors. Therefore polymorphisms in components of this pathway may lead to metabolic disorders. Aim: This study tested the impact of LRP5 polymorphism
Nima Montazeri-Najafabady +4 more
doaj +1 more source
Wnt Signaling in Neural Crest Ontogenesis and Oncogenesis. [PDF]
, 2019 Neural crest (NC) cells are a temporary population of multipotent stem cells that generate a diverse array of cell types, including craniofacial bone and cartilage, smooth muscle cells, melanocytes, and peripheral neurons and glia during embryonic ...
Hao, Hongyan +4 more
core +2 more sources