Results 201 to 210 of about 97,171 (272)

Disentangled Assembly Graphs Reveal Hidden Eukaryotic Diversity in eDNA Metagenomic Data

open access: yesMolecular Ecology Resources, Volume 26, Issue 3, April 2026.
ABSTRACT Genome assembly graphs contain valuable yet frequently overlooked information that can enhance assembly completeness by revealing contig connectivity. Here, we demonstrate how leveraging these information‐rich structures enables the discovery of hidden microeukaryotic diversity in environmental DNA shotgun metagenomic datasets.
Manon Mireille Geerts   +4 more
wiley   +1 more source

The Therapeutic Potential of Farm Dust Extracts in a Mouse Model of Eosinophilic Inflammation

open access: yesAllergy, Volume 81, Issue 4, Page 1173-1192, April 2026.
Farm dust extract (FDE) treatment reduces airway eosinophilia, mucus overproduction, and MHC‐II expression on DCs, limiting antigen presentation and Th2 inflammation. It increases PD‐L1 on DCs, promoting T cell deactivation. Additionally, FDE enhances Tregs and upregulates CTLA‐4, reinforcing suppression.
Rabia Ülkü Korkmaz   +16 more
wiley   +1 more source

Structural and organisational impacts of peri‐operative enhanced care services in the UK: a Retrospective Evaluation of Postoperative Alternatives to Critical Care (REPACC)

open access: yesAnaesthesia, Volume 81, Issue 4, Page 500-512, April 2026.
Summary Introduction The enhanced care model of peri‐operative care has evolved to meet increasing surgical demand, aiming to relieve pressure on critical care and prevent unnecessary cancellation of surgery. Despite widespread adoption of these facilities in the UK, no resources currently describe the national landscape of enhanced care or the ...
Christopher Oddy   +330 more
wiley   +1 more source

Roles of TIF1β in Leukemic Stem Cell Through SETDB1‐Dependent and Independent Mechanisms

open access: yesCancer Science, Volume 117, Issue 4, Page 896-903, April 2026.
In leukemic stem cell, BCR::ABL cooperates with TIF1β to open chromatin at oncogenes and close chromatin at differentiation regulators, driving leukemic reprogramming. In TIF1β‐deficient stem cell, the loss of TIF1β inverts this balance, showing closed chromatin at oncogenes and open chromatin at differentiation regulators.
Mariko Morii, Sho Kubota, Goro Sashida
wiley   +1 more source

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