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Assessment of an LSDV-Vectored Vaccine for Heterologous Prime-Boost Immunizations against HIV [PDF]
The modest protective effects of the RV144 HIV-1 vaccine trial have prompted the further exploration of improved poxvirus vector systems that can yield better immune responses and protection. In this study, a recombinant lumpy skin disease virus (LSDV) expressing HIV-1 CAP256.SU gp150 (Env) and a subtype C mosaic Gag was constructed (LSDVGC5) and ...
Rosamund Chapman +2 more
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Acta Tropica, 2023
Lumpy skin disease (LSD) is an economically important poxviral disease endemic to Asia, Europe, and Africa. Recently, LSD has spread to naïve countries, including India, China, Bangladesh, Pakistan, Myanmar, Vietnam, and Thailand. Here, we describe the complete genomic characterization of LSDV from India, LSDV-WB/IND/19 isolated from an LSD affected ...
Amit Kumar, Gnanavel Venkatesan
exaly +3 more sources
Lumpy skin disease (LSD) is an economically important poxviral disease endemic to Asia, Europe, and Africa. Recently, LSD has spread to naïve countries, including India, China, Bangladesh, Pakistan, Myanmar, Vietnam, and Thailand. Here, we describe the complete genomic characterization of LSDV from India, LSDV-WB/IND/19 isolated from an LSD affected ...
Amit Kumar, Gnanavel Venkatesan
exaly +3 more sources
LSDV-Vectored SARS-CoV-2 S and N Vaccine Protects against Severe Clinical Disease in Hamsters [PDF]
The SARS-CoV-2 pandemic demonstrated the need for potent and broad-spectrum vaccines. This study reports the development and testing of a lumpy skin disease virus (LSDV)-vectored vaccine against SARS-CoV-2, utilizing stabilized spike and conserved nucleocapsid proteins as antigens to develop robust immunogenicity.
Warren de Moor +2 more
exaly +5 more sources
International Journal of Biological Macromolecules
Lumpy skin disease caused by the lumpy skin disease virus (LSDV) infection causes significant economic losses to the cattle industry in many countries worldwide. The genetic homology between LSDV and both goat pox virus (GTPV) and sheep pox virus (SPPV) can reach around 97 %, indicating a high level of serological similarity.
军洋 房, Xuefeng Qi, Qinghong Xue
exaly +3 more sources
Lumpy skin disease caused by the lumpy skin disease virus (LSDV) infection causes significant economic losses to the cattle industry in many countries worldwide. The genetic homology between LSDV and both goat pox virus (GTPV) and sheep pox virus (SPPV) can reach around 97 %, indicating a high level of serological similarity.
军洋 房, Xuefeng Qi, Qinghong Xue
exaly +3 more sources
Approximating the bias of the LSDV estimator for dynamic unbalanced panel data models [PDF]
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
exaly +3 more sources
2022
Lumpy skin disease (LSD) is an economically important poxviral disease endemic to Asia, Europe, and Africa. Recently, LSD has spread to naïve countries, including India, China, Bangladesh, Pakistan, Myanmar, Vietnam, and Thailand. Here, we describe the complete genomic characterization of LSDV from India, LSDV-WB/IND/19 isolated from a calf in Vero ...
Amit Kumar +8 more
openaire +1 more source
Lumpy skin disease (LSD) is an economically important poxviral disease endemic to Asia, Europe, and Africa. Recently, LSD has spread to naïve countries, including India, China, Bangladesh, Pakistan, Myanmar, Vietnam, and Thailand. Here, we describe the complete genomic characterization of LSDV from India, LSDV-WB/IND/19 isolated from a calf in Vero ...
Amit Kumar +8 more
openaire +1 more source
The Importance of Quality Control of LSDV Live Attenuated Vaccines for Its Safe Application in the Field [PDF]
Vaccination is an effective approach to prevent, control and eradicate diseases, including lumpy skin disease (LSD). One of the measures to address farmer hesitation to vaccinate is guaranteeing the quality of vaccine batches. The purpose of this study was to demonstrate the importance of a quality procedure via the evaluation of the LSD vaccine ...
andy Haegeman, Kris De Clercq
exaly +4 more sources
Lumpy Skin Disease and Vectors of LSDV
2019Lumpy skin disease (LSD) is a viral disease of cattle caused by lumpy skin disease virus (LSDV). LSDV shares high degree of sequence homology with goatpox virus (GTPV) and sheeppox virus (SPPV), the two other members of the genus Capripoxvirus of the family Poxviridae. Genetically LSDV is a double-stranded DNA genome of approximately 151 kbp. LSD is an
Esayas Gelaye, Charles Euloge Lamien
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Poxviridae Protein kinases as targets for control of LSDV , Monkeypox like outbreaks
2023Lumpy skin disease virus has infected cows across the world resulting in the death or destruction of at least a million cows. Poxviridae family includes 88 such viruses that cause deadly diseases like smallpox, monkeypox and lumpy skin disease. Pox virus induced infections have been known to be sporadic and zoonotic.
Ramars Amanchy +4 more
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