Results 101 to 110 of about 869,268 (413)

The lumbar spine has an intrinsic shape specific to each individual that remains a characteristic throughout flexion and extension [PDF]

, 2014
Peer ...
Aspden, Richard M, Barr, Rebecca J, Cooper, Kay, Meakin, Judith R, Pavlova, Anastasia V   +4 more
core   +2 more sources

In Vivo Cytosolic Delivery of Biomolecules into Neurons for Super‐Resolution Imaging and Genome Modification

Advanced Science, EarlyView.
The N1 peptide specifically targets neurons, enabling cytosolic delivery of fluorescent dyes and proteins for super‐resolution imaging and functional genetic modification. Abstract Efficient delivery of biomolecules into neurons has significant impacts on therapeutic applications in the central nervous system (CNS) and fundamental neuroscience research.
Xiaoqian Ge, Joseph B. Wekselblatt, Scott Elmore, Bo Wang, Tongtong Wang, Renjinming Dai, Tingting Zhang, Harsh Dave, Mohammadaref Ghaderi, Athul Raj Anilkumar, Bill Wang, Shashank R. Sirsi, Jung‐Mo Ahn, Mikhail G. Shapiro, Yuki Oka, Carlos Lois, Zhenpeng Qin   +16 more
wiley   +1 more source

Differences in the Incidence of Symptomatic Cervical and Lumbar Disc Herniation According to Age, Sex and National Health Insurance Eligibility: A Pilot Study on the Disease’s Association with Work

International Journal of Environmental Research and Public Health, 2018
The aim of this research was to identify the differences in the incidence of symptomatic cervical and lumbar disc herniation according to age, sex, and national health insurance eligibility.
Youngki Kim, Dongmug Kang, Il-ho Lee, Se-Yeong Kim   +3 more
semanticscholar   +1 more source

Mechanical Load‐Induced Upregulation of Talin2 through Non‐Canonical Deubiquitination of OTUB1 Drives Facet Joint Osteoarthritis Pathogenesis

Advanced Science, EarlyView.
Facet joint osteoarthritis (FJOA), prevalent in the elderly, involves Talin2 upregulation promoting ECM degradation while suppressing synthesis. Mechanical load stabilizes Talin2 via OTUB1‐mediated non‐canonical deubiquitination, driving CCL2 expression that recruits immune cells, exacerbating inflammatory joint degeneration.
Yizhen Huang, Heng Sun, Haojie Chen, Xiangpeng Wang, Junduo Zhao, Yang Jiao, Hongyi Zhou, Haoyu Cai, Jiafeng Dai, Xuan Huang, Weiyun Chen, Jianxiong Shen   +11 more
wiley   +1 more source

A Localisation-Segmentation Approach for Multi-label Annotation of Lumbar Vertebrae using Deep Nets [PDF]

arXiv, 2017
Multi-class segmentation of vertebrae is a non-trivial task mainly due to the high correlation in the appearance of adjacent vertebrae. Hence, such a task calls for the consideration of both global and local context. Based on this motivation, we propose a two-staged approach that, given a computed tomography dataset of the spine, segments the five ...
arxiv  

Bandverbindungen der Dornfortsätze der Wirbelsäule [PDF]

, 1985
In the cervical region the fibres of the interspinous and nuchal ligaments pass in an anteroc ranial direction: they act against diminishing of the cervical lordosis.
Frick, H., Prestar, F.-J., Putz, Reinhard   +2 more
core   +1 more source

Locus Coeruleus Noradrenergic‐Spinal Projections Contribute to Electroacupuncture‐Mediated Antinociception in Postoperative Pain in Mice

Advanced Science, EarlyView.
How locus coeruleus noradrenergic‐spinal projections and subsequent α2A adrenoceptors‐CaMKII signaling cascades contribute to electroacupuncture‐induced antinociception in postoperative pain in mice is described. Abstract Postoperative pain remains a significant challenge in healthcare.
Wen‐Guang Chu, Ru Zhang, Hai‐Tao Li, Ying‐Chun Li, Hui Ding, Zhen‐Zhen Li, Wen‐Juan Han, Fei Wang, Xing‐Xing Zheng, Hong‐Hui Mao, Hua Yuan, Sheng‐Xi Wu, Rou‐Gang Xie, Ceng Luo   +13 more
wiley   +1 more source

Double gene mutations of LRSAM1 and REEP1 and a new REEP1 mutation site found in a patient with amyotrophic lateral sclerosis with subjective paresthesia: A case report

Ibrain, EarlyView., 2023
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by selective degeneration of upper and lower motor neurons. Leucine‐rich repeats and sterility α mutations in motif 1 (LRSAM1) has been proven to be involved in the pathogenesis of ALS.
Ji‐Yao Qin, Zun‐Lin Zhou, Yuan‐Qing Zhou, Ya Chen, Xiao‐Yan Yang, Hai‐Qing Zhang, Zu‐Cai Xu   +6 more
wiley   +1 more source

Comparison of the spine kinematics by defining lumbar as single and multi-segmental in completing critical daily task

Journal of Mechanical Engineering and Sciences, 2020
The change of the spinal curvature in completing a variety of daily tasks is essential to independent living. There is still a lack of studies highlighting the lumbar segmental contribution during sit-to-stand (STS) and stand-to-flexion (STF) usingnon ...
W.A.A Saad, M.A. Mat Dzahir, S.I Yamamoto, M. Hussein, M. Mohamad, S.M. Saad, M.A.M Dzahir, A. Azaman   +7 more
doaj   +1 more source

Predictive simulation of single-leg landing scenarios for ACL injury risk factors evaluation [PDF]

arXiv, 2022
The Anterior Cruciate Ligament rupture is a very common knee injury during sport activities. Landing after a jump is one of the most prominent human body movement scenarios that can lead to such an injury. The landing - related Anterior Cruciate Ligament (ACL) injury risk factors have been in the spotlight of research interest.
arxiv