Results 101 to 110 of about 124,017 (271)

Mechanical Load‐Induced Upregulation of Talin2 through Non‐Canonical Deubiquitination of OTUB1 Drives Facet Joint Osteoarthritis Pathogenesis

open access: yesAdvanced Science, EarlyView.
Facet joint osteoarthritis (FJOA), prevalent in the elderly, involves Talin2 upregulation promoting ECM degradation while suppressing synthesis. Mechanical load stabilizes Talin2 via OTUB1‐mediated non‐canonical deubiquitination, driving CCL2 expression that recruits immune cells, exacerbating inflammatory joint degeneration.
Yizhen Huang   +11 more
wiley   +1 more source

CQ-VAE: Coordinate Quantized VAE for Uncertainty Estimation with Application to Disk Shape Analysis from Lumbar Spine MRI Images [PDF]

open access: yesarXiv, 2020
Ambiguity is inevitable in medical images, which often results in different image interpretations (e.g. object boundaries or segmentation maps) from different human experts. Thus, a model that learns the ambiguity and outputs a probability distribution of the target, would be valuable for medical applications to assess the uncertainty of diagnosis.
arxiv  

Lumbar puncture [PDF]

open access: yesEmergency Medicine Australasia, 2014
Ben Butson, Paul Kwa
openaire   +3 more sources

Functional asymmetry of the spine in standing and sitting positions [Funkční asymetrie páteře vstoje a vsedě]

open access: yesActa Universitatis Palackianae Olomucensis. Gymnica, 2010
BACKGROUND: A sedentary lifestyle, together with functional asymmetry of the body, are potentially dysfunctional factors. OBJECTIVE: In this project, the authors are trying to identify the connections between a sedentary lifestyle and the amount of ...
Rafał Gnat   +2 more
doaj  

Machine-agnostic Automated Lumbar MRI Segmentation using a Cascaded Model Based on Generative Neurons [PDF]

open access: yes
Automated lumbar spine segmentation is very crucial for modern diagnosis systems. In this study, we introduce a novel machine-agnostic approach for segmenting lumbar vertebrae and intervertebral discs from MRI images, employing a cascaded model that synergizes an ROI detection and a Self-organized Operational Neural Network (Self-ONN)-based encoder ...
arxiv   +1 more source

Preoperative sarcopenia negatively impacts short‐ and long‐term outcomes of rectal cancer: A propensity score‐matched analysis

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
This study examined the effects of skeletal muscle mass on the short‐ and long‐term outcomes of rectal cancer. This study revealed that preoperative sarcopenia was associated with more total postoperative complications, more anastomotic leakage, and worse survival in rectal cancer patients.
Shinya Abe   +9 more
wiley   +1 more source

Unique bone microanatomy reveals ancestry of subterranean specializations in mammals

open access: yesEvolution Letters, Volume 6, Issue 6, Page 552-561, December 2022., 2022
Abstract Acquiring a subterranean lifestyle entails a substantial shift for many aspects of terrestrial vertebrates’ biology. Although this lifestyle is associated with multiple instances of convergent evolution, the relative success of some subterranean lineages largely remains unexplained.
Eli Amson   +6 more
wiley   +1 more source

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