Results 81 to 90 of about 27,474 (246)

PACS‐2 Mitigates NPSC Apoptosis and Intervertebral Disc Degeneration by Preserving MAM Integrity via the SP1/LRRK2/Mfn2 Axis

Advanced Science, Volume 13, Issue 4, 19 January 2026.
This study investigates the role of PACS‐2 in IDD, demonstrating that it suppresses the nuclear translocation of SP1, thereby downregulating its downstream target LRRK2. This reduces LRRK2‐mediated ubiquitination and degradation of Mfn2 through the JNK pathway, preserving MAM integrity and promoting NPSC survival.
Liang Kang, Jiaqi Wang, Chenhao Zhao, Qiuwei Li, Zhigang Zhang, Huaqing Zhang, Chongyu Jia, Luping Zhou, Yanxin Wang, Yu Chen, Kaixuan Li, Xu Yan, Jie Fang, Haibao Wang, Dandan Wang, Pingping Su, Jingyu Zhang, Zhiwei Chen, Renjie Zhang, Cailiang Shen   +19 more
wiley   +1 more source

Co-occurrence of lumbar spondylolysis and lumbar disc herniation with lumbosacral nerve root anomaly

Journal of Craniovertebral Junction and Spine, 2014
Lumbosacral nerve root anomalies are the leading cause of lumbar surgery failures. Although co-occurrence of lumbar spondylolysis and disc herniation is common, it is very rare to observe that a nerve root anomaly accompanies these lesions. A 49-year-old
Tevfik Yilmaz, Yahya Turan, Ismail Gulsen, Sedat Dalbayrak   +3 more
doaj   +1 more source

Diagnosis and Treatment Report of a Case of Small Hepatocellular Carcinoma With Left Adrenal Metastasis and Hemorrhage in an Elderly Male Hepatitis B Virus Carrier

Clinical Case Reports, Volume 14, Issue 1, January 2026.
ABSTRACT A 64‐year‐old male hepatitis B virus (HBV) carrier was admitted to the hospital due to long‐term left lumbodorsal pain. He reported having suffered from lumbodorsal pain for 3 months. After visiting our hospital, he underwent a complete urinary system computed tomography (CT) scan, which revealed masses in the thyroid gland and liver ...
Guanyu Zhou, Fan Wu, Tianhe Feng, Tianqi Lin   +3 more
wiley   +1 more source

The Relationship of Lumbar Multifidus Muscle Change to Disc Hernia and Low Back Pain: An Magnetic Resonance Imaging Study

İstanbul Medical Journal, 2019
Introduction:Our aim was to evaluate the relationship between lumbar multifidus (LM) muscle atrophy and lumbar disc herniation by magnetic resonance imaging (MRI) findings in patients with low back pain.Methods:Lumbar MRI of 264 patients aged between 18 ...
Emrah Sayıt
doaj   +1 more source

Unforeseen Complications: Cauda Equina Syndrome After Vaginoplasty Combined With Epidural Analgesia

Clinical Case Reports, Volume 14, Issue 1, January 2026.
ABSTRACT This case describes the first postoperative complication of cauda equina syndrome following gender affirmation surgery. Postoperatively, an epidural catheter was placed for pain management. Despite its intended benefits, the patient developed symptoms of cauda equina syndrome, a rare but serious neurological condition possibly related to ...
Toni P. Seppälä, Kaisu Ojala
wiley   +1 more source

Lumbar disc herniation: long-term outcomes after mini-open discectomy [PDF]

, 2019
Tianhang Xie, Xi Yang, Yueming Song
openalex   +1 more source

Pyroptosis in Peripheral Neuropathy: From Molecular Mechanisms to Therapeutic Targeting

CNS Neuroscience &Therapeutics, Volume 32, Issue 1, January 2026.
Pyroptosis is a key inflammatory cell death pathway in peripheral neuropathy, with opposing roles: it perpetuates neuropathic pain but can be induced to kill neuroblastoma cells. This review consolidates mechanistic understanding and therapeutic strategies, arguing for a shift from disease‐centric to target‐centric treatment approaches to improve ...
Jinhuan Wei, Mingyue Liuyuan, Zhixin Ye, Xueying Wang, Xueli Zhou, Yifan Shan, Cheng He, Chunting Zhu, Chicheng Zhou, Jingyin Bao, Yonghui Zhang, Gang Chen   +11 more
wiley   +1 more source

Application progress on Chinese herb fumigation for lumbar disc herniation patients receiving conservative treatment

Huli yanjiu, 2015
AbstractIt summed up the application status quo of Chinese herb fumigation for lumbar disc herniation patients receiving conservative treatment，improved the traditional Chinese medicine nursing content of lumbar disc herniation patients with ...
郭闯, 李艳秋, 王丽芹, 等
doaj  

Geranium Essential Oil Use for Human Health: A Systematic Review of Clinical Evidence

Flavour and Fragrance Journal, Volume 41, Issue 1, Page 24-36, January 2026.
Geranium essential oil (Pelargonium graveolens) demonstrates efficacy in alleviating anxiety, pain and dermatological conditions, supporting its use as a safe, low‐cost complementary therapy. However, further controlled studies are needed to standardise protocols and confirm its benefits.
Amanda Karina Santos Vieira, Luiza Paes Barbosa, Juliana Rizzo Gnatta   +2 more
wiley   +1 more source

Ultrasound‐Guided Near‐Nerve Needle Recording in Sensory Conduction Study of the Superficial Fibular Nerve

Muscle &Nerve, Volume 73, Issue 1, Page 97-102, January 2026.
ABSTRACT Introduction/Aims The sensory nerve action potential (SNAP) of the superficial fibular nerve (SFN) is occasionally small and difficult to obtain using conventional surface recording (SR) or near‐nerve needle recording. This study aimed to demonstrate a novel method of sensory conduction study of the SFN using ultrasound‐guided near‐nerve ...
Haruki Nakano, Aishi Okazaki, Ryuichi Saura   +2 more
wiley   +1 more source