Results 61 to 70 of about 228,011 (281)

Using a novel virtual-reality simulator to assess performance in lumbar puncture: a validation study

BMC Medical Education, 2023
Background A lumbar puncture procedure’s success depends on a competent physician minimizing the risk of failing to get a sample and avoiding complications such as post-dural headache.
Sujun Xie, Søren Grimstrup, Leizl Joy Nayahangan, Zheng Wang, Xing Wan, Lars Konge   +5 more
doaj   +1 more source

Association Between Neurofilament Light Chain and Real‐World Ambulatory Function in Progressive MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurofilament light chain (NfL) is a biomarker of neuroaxonal injury in multiple sclerosis (MS), yet associations with functional outcomes remain unclear. Longitudinal associations between serum NfL (sNfL) and daily step count (STEPS) from wearable devices were assessed in a large international progressive MS cohort.
Gabby B. Joseph, Megan McCune, Riley Bove, Ahmed Abdelhak, Bruce A. C. Cree, Valerie J. Block   +5 more
wiley   +1 more source

Subjective Cognitive Concerns and Cognitive Trajectories in Parkinson's Disease: Biomarker Impact

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the relationship of subjective cognitive concerns (SCC) with biomarkers of Alzheimer's disease (AD), neurodegeneration, and Parkinson's disease (PD) and domain‐specific cognitive trajectories among cognitively unimpaired persons with de novo PD. Method Cognitively unimpaired participants with SCC (n = 294) and without SCC (
Francesca V. Lopez, Fareshte Erani, Katherine J. Bangen, David G. Coughlin, Douglas Galasko, Kelsey R. Thomas   +5 more
wiley   +1 more source

Cerebral venous thrombosis as a complication of intracranial hypotension after lumbar puncture

BMJ Neurology Open, 2020
Background Optic neuritis is recognised by the international classification of headache disorders as a painful cranial nerve lesion. A lumbar puncture may be performed in the investigation of optic neuritis.
Cecilia Cappelen-Smith, Leon Stephen Edwards, Ramesh Cuganesan   +2 more
doaj   +1 more source

Correlation between blood glucose and cerebrospinal fluid glucose levels in patients with differences in glucose metabolism

Frontiers in Neurology, 2023
ObjectivesWe aimed to determine a method to identify normal cerebrospinal fluid (CSF) glucose levels by examining the correlation between blood and CSF glucose levels in patients with normal and abnormal glucose metabolism.MethodsOne hundred ninety-five ...
Qing Che Tan, Qing Che Tan, Xiao Wei Xing, Jia Tang Zhang, Mian Wang He, Yu Bao Ma, Lei Wu, Xiaolin Wang, Hong Fen Wang, Sheng Yuan Yu   +9 more
doaj   +1 more source

Cumulative occupational lumbar load and lumbar disc disease : results of a German multi-center case-control study (EPILIFT) [PDF]

, 2009
Background The to date evidence for a dose-response relationship between physical workload and the development of lumbar disc diseases is limited. We therefore investigated the possible etiologic relevance of cumulative occupational lumbar load to lumbar
Grifka, Joachim, Ditchen Dirk, Joachim Grifka, Hofmann Friedrich, Martina Michaelis, Ellegast Rolf, Oliver Linhardt, Annekatrin Bergmann, Elsner Gine, Petereit-Haack, Gabriela, Jäger Matthias, Rolf Ellegast, Ditchen, Dirk Marcel, Luttmann, Alwin, Schumann Barbara, Seidler, Andreas, Haerting Johannes, Seidler Andreas, Luttmann Alwin, Jäger, Matthias, Grifka Joachim, Friedrich Hofmann, Schumann, Barbara, Andreas Seidler, Michaelis, Martina, Johannes Haerting, Bergmann, Annekatrin, Alwin Luttmann, Haerting, Johannes, Elsner, Gine, Ulrich Bolm-Audorff, Ellegast, Rolf, Bolm-Audorff, Ulrich, Barbara Schumann, Michaelis Martina, Dirk Ditchen, Hofmann, Friedrich, Petereit-Haack Gabriela, Bolm-Audorff Ulrich, Gine Elsner, Gabriela Petereit-Haack, Ellegast, Rolf Peter, Linhardt Oliver, Ditchen, Dirk, Bergmann Annekatrin, Linhardt, Oliver, Matthias Jäger   +46 more
core   +2 more sources

Cerebrospinal Fluid Over Plasma Links Analytes to Cognitive Decline in Older Adults at Risk for Alzheimer's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To identify inflammatory analytes in cerebrospinal fluid (CSF) and plasma associated with cognitive decline in cognitively normal (CN) older adults at risk for Alzheimer's disease (AD). Methods In a longitudinal study of 118 CN older adults (65–80 years, 54% APOE ε4, 26% preclinical AD), 1331 CSF and 1501 plasma analytes were ...
Jagan A. Pillai, Audrey Zhu, Chunxuan Ma, Ming Wang, Yifan Yang, Lynn M. Bekris, Maria Khrestian, Frank P. DiFilippo, Mikhail Nasrallah, Aaron Burberry, James B. Leverenz, Yuan Hou, Feixiong Cheng, Stephen M. Rao   +13 more
wiley   +1 more source

Lumbar puncture in patients using anticoagulants and antiplatelet agents

Arquivos de Neuro-Psiquiatria, 2016
The use of anticoagulants and antiplatelet agents has largely increased. Diagnostic lumbar puncture in patients taking these drugs represents a challenge considering the opposing risks of bleeding and thrombotic complications.
Renan Domingues, Gustavo Bruniera, Fernando Brunale, Cristóvão Mangueira, Carlos Senne   +4 more
doaj   +1 more source

Dural tear from diagnostic lumbar puncture followed by long-term morbidity: a case report

Neurological Research and Practice, 2020
Background Lumbar punctures are performed in different medical settings and are a key procedure in the diagnosis of several neurological conditions. Complications are rare and generally self-limiting.
Aleksander Fjeld Haugstvedt, Inger Birgitte Havsteen, Hanne Christensen   +2 more
doaj   +1 more source

Early Clinical and Cerebrospinal Fluid Predictors of 1‐Year Recurrence in Autoimmune GFAP Astrocytopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Autoimmune glial fibrillary acidic protein astrocytopathy (GFAP‐A) is an inflammatory central nervous system disorder with variable outcomes. Relapse occurs in a subset of patients, but early predictors remain unclear. We aimed to identify admission‐available features associated with 1‐year recurrence and develop an interpretable ...
Qingting Hong, Yuping Xiao, Yuhan Wu, Ziyuan Huang, Weishan Liang, Li Xiao, Yaqing Shu, Tingting Lu, Yanyu Chang, Wei Qiu, Yuge Wang   +10 more
wiley   +1 more source