Results 231 to 240 of about 90,647 (304)

Effect of artificial gravity on calcaneal bone marrow adipose tissue and mineral content in female and male participants in 60 days of bed rest

Experimental Physiology, EarlyView.
Abstract Modulation of bone marrow adipose tissue (BMAT) with prolonged inactivity was reported in haemopoietic but not in non‐haemopoietic bones. This prospective randomized controlled trial submitted 16 men and 8 women to 60 days of 6° head‐down‐tilt bed rest.
Tammy Liu, Gerd Melkus, Tim Ramsay, Alain Berthiaume, Gabriele Armbrecht, Guy Trudel   +5 more
wiley   +1 more source

50% body weight loading reduces stature increases and lumbar disc expansion from 4 h hyper‐buoyancy floatation versus 15 min sitting upright

Experimental Physiology, EarlyView.
Abstract Microgravity is associated with stature increases, back pain and post‐flight intervertebral disc (IVD) herniation. This study aims to determine whether 30 s seated 50% body weight (BW) axial loading is comparable to 15 min sitting upright in 1 g upon changes in stature, anterior lumbar IVD height (via ultrasound), passive vertebral stiffness ...
David Marcos‐Lorenzo, Christina Lysandrou, Laura Sudres, Alfonso Gil‐Martinez, Jaap Swanenburg, James Edward Clark, David Andrew Green   +6 more
wiley   +1 more source

Opportunistic use of chest low-dose computed tomography (LDCT) imaging for low bone mineral density and osteoporosis screening: cutoff thresholds for the attenuation values of the lower thoracic and upper lumbar vertebrae. [PDF]

Quant Imaging Med Surg
Pan YL, Wu YB, Wang HG, Yu TH, He D, Lu XJ, Zhao FF, Ma HF, Wang YJ, Cai YK.   +9 more
europepmc   +1 more source

Molecular pathophysiology of chronic kidney disease–mineral and bone disorder: Focus on the fibroblast growth factor 23–Klotho axis and bone turnover dynamics

Experimental Physiology, EarlyView.
Abstract Chronic kidney disease–mineral and bone disorder (CKD‐MBD) is a major complication of chronic kidney disease (CKD), characterized by disruptions in mineral metabolism, abnormal bone turnover and vascular calcification, which collectively increase the risk of fractures and cardiovascular disease.
Alief Waitupu, Laras Pratiwi, Henry Sutanto, Djoko Santoso, Decsa Medika Hertanto   +4 more
wiley   +1 more source

Osteochondroma - lumbar vertebra / spine

, 2019
openaire   +1 more source

Secretome and Pathway Analysis of Stress Induced Disc Degeneration In Vitro

JOR SPINE, Volume 9, Issue 2, June 2026.
Integrated secretome and phosphoprotein profiling of human nucleus pulposus cells revealed that IL‐1β and TLR2/6 activation induce a shared degenerative program, defined by consistent upregulation of IL‐6, IL‐8, GRO‐α, ICAM‐1, and MMP‐7 and convergence on NF‐κB/AP‐1 signaling.
Exarchos Kanelis, Andrea Nüesch, Joseph Snuggs, Christine Lyn Le Maitre, Leonidas G. Alexopoulos   +4 more
wiley   +1 more source

Viscoelastic and Morphologic Changes in the Lumbar Intervertebral Discs of the 5xFAD Mouse Model of Alzheimer's Disease

JOR SPINE, Volume 9, Issue 2, June 2026.
The intervertebral discs (IVDs) from mice with amyloid pathologies are larger, flatter, and exhibit increased energy absorption, making these IVDs more susceptible to damage. This heightened vulnerability may predispose elderly individuals with AD to disc injuries, accelerating IVD degeneration and spinal pain. ABSTRACT Background Chronic low back pain,
C. E. Gonzalez, C. A. Schurman, K. A. Wilson, B. Schilling, L. M. Ellerby, S. Y. Tang   +5 more
wiley   +1 more source

Measurement of the kinematics of the lumbar spine in vivo

, 2001
Allen, R., Nixon, M.S., Zheng, Y.
core  

A Network‐Based Approach to Understanding Key Signaling Pathways in Intervertebral Disc Biology

JOR SPINE, Volume 9, Issue 2, June 2026.
A literature‐based signaling network capturing the most relevant pathways in human nucleus pulposus cells was first constructed from curated biological evidence. The network was then translated into a system of ordinary differential equations to derive steady‐state solutions and define median baseline activity levels.
Sofia Tseranidou, Zerihun G. Workineh, Maria Segarra‐Queralt, Francis Kiptengwer Chemorion, Paola Bermudez‐Lekerika, Exarchos Kanelis, Katherine B. Crump, Benjamin Gantenbein, Leonidas G. Alexopoulos, Christine L. Le Maitre, Janet Piñero, Jérôme Noailly   +11 more
wiley   +1 more source

Patients With Chronic Low Back Pain Without Advanced Disk Degeneration Exhibit Gut Microbiome Dysbiosis: Evidence From an Age‐, Sex‐, and BMI‐Matched Pilot Study

JOR SPINE, Volume 9, Issue 2, June 2026.
Chronic low back pain in patients without advanced disc degeneration is associated with gut microbiome dysbiosis, marked by reduced microbial diversity and altered bacterial composition. These findings support a gut–disk axis in which impaired gut barrier integrity and systemic inflammation may contribute to disc inflammation, nociceptive fiber ...
Stone Sima, Thomas Jeffries, Alisha Sial, Suhani Sharma, Neha Chopra, Fan Zhang, Georgina Hold, Wentian Li, Ji Tu, Victor Chen, Ashish Diwan   +10 more
wiley   +1 more source