Results 241 to 250 of about 90,647 (304)

Deletion of a Pax1 Sex‐Associated Genomic Region Associated With Adolescent Idiopathic Scoliosis Leads to Disc Degeneration, Instability, and Vertebral Rotation in Mice

JOR SPINE, Volume 9, Issue 2, June 2026.
Overview of the effects of Pax1‐SAR deletion on gene expression, IVD degeneration, and resultant scoliotic‐like curvature between sexes. Proposed mechanism of sex‐dependent changes in gene expression in females (right) and males (left), resulting in sex‐dependent disc degeneration and scoliotic phenotypes.
Edward C. Moody, Emma M. Wade, Shuji Mizumoto, Jeremy McCallum‐Loudeac, Megan J. Wilson   +4 more
wiley   +1 more source

Inhibition of PLA2G15 Alleviates Palmitic Acid‐Induced Lysosomal Membrane Permeabilization in Human Nucleus Pulposus Cells During Intervertebral Disc Degeneration

JOR SPINE, Volume 9, Issue 2, June 2026.
LMP is responsible for lysosomal dysfunction in IDD. The lipid composition changes in the lysosomal membrane, mediated by PLA2G15, are the cause of LMP. The C/EBPα significantly promotes PLA2G15 expression under PA overload stress. Inhibition of PLA2G15 alleviates PA‐induced LMP by inhibiting the hydrolysis of lysosomal membrane phospholipids. ABSTRACT
Liqun Duan, Jiang Jiang, Shuangshuang Tu, Chuanfu Li, Yijun Dong, Yongjin Li, Wenzhi Zhang, Xi Chen   +7 more
wiley   +1 more source

Platelet‐Rich Fibrin Induces New Bone Formation to Promote Extreme Lateral Interbody Fusion of Spine in Rabbits

JOR SPINE, Volume 9, Issue 2, June 2026.
Preparation process of PRF and its promotion of intervertebral fusion. The rabbit lateral fusion model proves that PRF can promote the intervertebral fusion rate of allograft bone. In vitro experiments can be observed that PRF promotes the osteogenic expression of BMSCS.
Weijian Wang, Jiaqi Li, Han Wu, Sidong Yang, Shaorong Li, Wei Zhang   +5 more
wiley   +1 more source

Larger Lumbar Vertebral Body Osteophyte Volume Is Associated With Older Age and a More Caudal Vertebral Level in Individuals With Chronic Low Back Pain

JOR SPINE, Volume 9, Issue 2, June 2026.
Procrustes analysis was used to match osteophyte‐free lumbar vertebral bodies to lumbar vertebral bodies containing osteophytes. The volume of the reference library bone was subtracted to create an osteophyte model, from which regional osteophyte volumes were calculated.
Clarissa LeVasseur, Sabreen Megherhi, Matthew Mesoros, Gina McKernan, Richard Warwose, William Donaldson, Joon Y. Lee, Gwendolyn Sowa, William Anderst   +8 more
wiley   +1 more source

Entering a new era for exercise countermeasures in human spaceflight

Experimental Physiology, EarlyView.
Enrico De Martino, Patrick Swain, Kirsty Lindsay, Claire Bruce‐Martin, Ewoud Jacobs, Bradley Barbour, Chris Buckley, Adam C. McDonnell, Nick Caplan, Luke Hughes   +9 more
wiley   +1 more source

Intradiscal Cutibacterium acnes Sustains Modic Type 1‐Like Lesions Over Time in a Rat Lumbar Endplate Injury Model

JOR SPINE, Volume 9, Issue 2, June 2026.
Intradiscal C. acnes injection sustained MC1‐like lesions with persistent neutrophil sustenance in an etiology‐specific lumbar MC rat model. This suggests that patients with bacterial MC etiology may persist in painful MC1, highlighting C. acnes and neutrophils as potential targets to promote MC1‐to‐MC2 conversion and improve pain and disability ...
Irina Heggli, Alon Lai, Denise Iliff, Marco D. Burkhard, Niklas Koehne, Harsev Singh, Jonathan J. Huang, Alan C. Seifert, Damien Laudier, Noah Bonnheim, Levon Rodriguez, Timothy D. Jacobsen, James C. Iatridis   +12 more
wiley   +1 more source

On‐Scanner Correction of Gradient Nonlinearity Bias for Accurate Assessment of Diffusion Heterogeneity Across Bone Sites in Myelofibrosis Patients

Magnetic Resonance in Medicine, Volume 95, Issue 6, Page 3386-3395, June 2026.
ABSTRACT Purpose To improve accuracy of apparent diffusion coefficient (ADC) measurement across different bone‐marrow (BM) sites for myelofibrosis (MF) patients. Methods Vendor‐provided ADC gradient nonlinearity correction (GNC) was implemented for 41 MF study subjects on a 3T clinical scanner.
Dariya Malyarenko, Brian D. Ross, Johannes M. Peeters, Ajit Devaraj, Ramin Jafari, Humera Tariq, Kristen M. Pettit, Moshe Talpaz, Gary D. Luker, Thomas L. Chenevert   +9 more
wiley   +1 more source

Application of Digital, Web‐Based, and Online Strategies in Point of Care Ultrasound (POCUS) Training: A Scoping Review

Health Science Reports, Volume 9, Issue 5, May 2026.
ABSTRACT Background Ultrasound is a commonly used modality in healthcare. Point of care ultrasound (POCUS) is performed at the patient's bedside with many purported benefits. Aims Given its increasingly popularity, this scoping review examined the role of digital, web‐based, and online educational strategies for POCUS. Methods Adhering to Joanna Briggs
Jessica Hang, Sandhya Maranna, Nayana Parange, Saravana Kumar   +3 more
wiley   +1 more source

A Decade of Leadership and Impact: Celebrating 10 Years of the ORS Spine Section

JOR SPINE, Volume 9, Issue 2, June 2026.
Neharika Bhadouria, Rahul Gawri, Gabriela Graziani, Dennis E. Anderson, Ana V. Chee, Chitra L. Dahia, Ashish Diwan, Morgan B. Giers, Svenja Illien‐Junger, Anthony Kirilusha, David J. Nuckley, Derek H. Rosenzweig, Cheryle Séguin, Dmitriy Sheyn, Graciosa Q. Teixeira, Mauro Alini, Keita Ito, Robert L. Mauck, Daisuke Sakai, Jeannie Bailey, Aaron J. Fields, Sibylle Grad, Sarah E. Gullbrand, Nilsson Holguin, Rita Kandel, Zhen Li, Joshua Li, John T. Martin, Fackson Mwale, Grace D. O'Connell, Devina Purmessur, Nam Vo, Uruj Zehra, Nadeen O. Chahine, Lisbet Haglund, Judith A. Hoyland, Christine L. Le Maitre, Jeffrey C. Lotz, Makarand V. Risbud, Lachlan J. Smith, Simon Tang, James C. Iatridis, Karin Wuertz‐Kozak, Dino Samartzis   +43 more
wiley   +1 more source