Results 141 to 150 of about 5,782,344 (357)

Mitochondria‐Targeted Nanomotor: H2S‐Driven Cascade Therapy for Hepatocellular Carcinoma

Advanced Materials, EarlyView.
A mitochondrial‐targeted nanomotor integrates photodynamic therapy, mild photothermal therapy, and enzyme dynamic therapy into a self‐amplifying cascade through H2S‐driven metabolic reprogramming. Abstract Despite advances in combination therapies for cancer treatment, most strategies rely on modular‐additive designs that lack dynamic molecular cues to
Chengcheng Li, Xiaodong Ma, Shiji Fang, Biao Chen, Xinru Wang, Lingyun He, Xin Yang, Yuanqiang Li, Jessica M. Rosenholm, Zhongwei Zhao, Jiansong Ji, Hongbo Zhang   +11 more
wiley   +1 more source

High‐Throughput In Vivo Screening Using Barcoded mRNA Identifies Lipid Nanoparticles With Extrahepatic Tropism for In Situ Immunoengineering

Advanced Materials, EarlyView.
A high‐throughput in vivo mRNA LNP screening platform is developed and employed to screen a large library of 122 mRNA LNPs in vivo for delivery to immune, stromal, and parenchymal cells, identifying promising LNP candidates. A novel small particle flow cytometry‐based protein adsorption analysis method is utilized to interrogate protein corona ...
Alex G. Hamilton, Ajay S. Thatte, Junchao Xu, Zhangyi Luo, Hannah C. Safford, Kelsey L. Swingle, Jenna Muscat‐Rivera, Michael Kegel, Xuexiang Han, Ryann A. Joseph, Amanda M. Murray, Hannah C. Geisler, Ricardo C. Whitaker, Lulu Xue, Roman Spektor, Jilian R. Melamed, Drew Weissman, Michael J. Mitchell   +17 more
wiley   +1 more source

A cautionary note on the potential pitfalls of using N-terminal truncated CD63 to label small extracellular vesicles

Scientific Reports
Small extracellular vesicles (sEV) are nanosized vesicles that facilitate intracellular communication. A significant research obstacle is the isolation of sEV devoid of non-sEV contaminants.
Elias Sulaiman, Derek M. Yellon, Sean M. Davidson   +2 more
doaj   +1 more source

Recent Advances in Fluorescent Nanoparticles for Stimulated Emission Depletion Imaging

Biosensors
Stimulated emission depletion (STED) microscopy, as a popular super-resolution imaging technique, has been widely used in bio-structure analysis and resolving the dynamics of biological processes beyond the diffraction limit.
Liqing Qi, Songlin Liu, Jiantao Ping, Xingxing Yao, Long Chen, Dawei Yang, Yijun Liu, Chenjing Wang, Yating Xiao, Lubin Qi, Yifei Jiang, Xiaohong Fang   +11 more
doaj   +1 more source

Programmable Dimensional Lithography with Digital Micromirror Devices for Multifunctional Microarchitectures

Advanced Materials Technologies, EarlyView.
This review explores recent advances in digital micromirror device (DMD)‐based lithography, focusing on its programmable light modulation, multi‐material compatibility, and dimensional patterning strategies. It highlights innovations from optical system design to materials integration and multifunctional applications, positioning DMD lithography as a ...
Yubin Lee, Byungcheon Yoo, Chaeyeong Ryu, Jongwon Oh, Dahye Baek, Jiseok Lee   +5 more
wiley   +1 more source

Role of Hydrogen Bonding in Green Fluorescent Protein-like Chromophore Emission. [PDF]

, 2019
The fluorescence emission from green fluorescent protein (GFP) is known to be heavily influenced by hydrogen bonding between the core fluorophore and the surrounding side chains or water molecules.
Chen, Xiaofeng, Jiang, Jun, Luo, Yi, Miao, Hui, Nian, Shifeng, Sharman, Edward, Yang, Li, Zhang, Guozhen, Zhang, Xuepeng   +8 more
core  

Fabrication Technologies for Soft, Multimaterial Optical Fibers for In Vivo Diagnostics and Phototherapy, With a Focus on Extrusion Printing

Advanced Materials Technologies, EarlyView.
Soft multimaterial optical fibers integrate multiple functionalities—such as waveguiding, side emission, sensing, drug delivery or actuation—into a single filament for wearable, implantable, and tissue‐integrated devices for diagnostics and phototherapy.
Zahra Kafrashian, Jun Feng, Aránzazu del Campo   +2 more
wiley   +1 more source

INFLUENCE OF pH ON THE SPECTRAL-LUMINESCENT CHARACTERISTICS OF THE SOFT PROTEIN CROWN OF SILVER NANOPARTICLES

, 2022
F. D. Davidov, А. А. Кулешова, A. M. Saletsky   +2 more
openalex   +1 more source

End‐to‐End Sensing Systems for Breast Cancer: From Wearables for Early Detection to Lab‐Based Diagnosis Chips

Advanced Materials Technologies, EarlyView.
This review explores advances in wearable and lab‐on‐chip technologies for breast cancer detection. Covering tactile, thermal, ultrasound, microwave, electrical impedance tomography, electrochemical, microelectromechanical, and optical systems, it highlights innovations in flexible electronics, nanomaterials, and machine learning.
Neshika Wijewardhane, Lyn I. Jones, Richard M. Martin, Helen Winter, Faezeh Arab Hassani   +4 more
wiley   +1 more source

Regulating room temperature phosphorescence of carbazole quaternization pyridine in polymer through Hofmeister effect

Aggregate
Hofmeister effect is a famous physical chemistry phenomenon that was reported a hundred years ago, which firstly refers to the action of certain salts to decrease the solubility of proteins while others increase.
Runying He, Yun Yang, Qian Zhou, Shasha Chang, Yi Cheng, Xiurong Ma, Yonggang Shi, Liyan Zheng, Qiue Cao   +8 more
doaj   +1 more source