Results 261 to 270 of about 85,967 (327)

Eukaryotic initiation factors eIF4F and eIF4B promote translation termination upon closed-loop formation. [PDF]

Nucleic Acids Res
Shuvalova E, Shuvalov A, Al Sheikh W, Ivanov AV, Biziaev N, Egorova TV, Dmitriev SE, Terenin IM, Alkalaeva E.   +8 more
europepmc   +1 more source

Nanoneedle‐Based Electroporation for Efficient Manufacturing of Human Primary Chimeric Antigen Receptor Regulatory T‐Cells

Advanced Science, EarlyView.
Low reproducibility and inefficient gene transfer hamper clinical manufacturing of chimeric antigen receptor regulatory T cells (CAR Tregs). Nanoneedle mediated electroporation generates primary human CAR Tregs under good manufacturing practice conditions with superior efficiency compared to viral transduction.
Ningjia Sun, Cong Wang, William Edwards, Yikai Wang, Xiangrong L. Lu, Chenlei Gu, Samuel McLennan, Panicos Shangaris, Peng Qi, Daniela Mastronicola, Cristiano Scottà, Giovanna Lombardi, Ciro Chiappini   +12 more
wiley   +1 more source

Luminescent Lanthanide Infinite Coordination Polymers for Ratiometric Sensing Applications. [PDF]

Molecules
Song Z, Hao Y, Long Y, Zhang P, Zeng R, Chen S, Chen W.   +6 more
europepmc   +1 more source

Metal–Organic Frameworks: Unlocking New Frontiers in Cardiovascular Diagnosis and Therapy

Advanced Science, EarlyView.
Metal–organic frameworks (MOFs), are composed of metal ions and bridging organic ligands, are recognized as an excellent platform for host‐gust chemistry. Its rich structural composition, modifiable sites, and multilevel pore distribution can provide delivery and release of signaling molecules, probes, and therapeutic drugs, which exhibit great medical
Qilu Wu, Yuxiao Feng, Mathilde Lepoitevin, Meng Yu, Christian Serre, Jun Ge, Yuan Huang   +6 more
wiley   +1 more source

Application of a novel RNA-protein interaction assay to develop inhibitors blocking RNA-binding of the HuR protein. [PDF]

Front Genet
Filcenkova L, Reisbitzer A, Joseph BP, Weber V, Carloni P, Rossetti G, Krauß S.   +6 more
europepmc   +1 more source

The Transcription Factor WFZP Interacts with the Chromatin Remodeler TaSYD to Regulate Root Architecture and Nitrogen Uptake Efficiency in Wheat

Advanced Science, Volume 12, Issue 15, April 17, 2025.
Root development and nitrogen uptake efficiency are vital for crop productivity. Du, Li, Jiang, et al. show that the wheat transcription factor WFZP and the chromatin remodeler TaSYD form a complex within the nucleus, thereby activating the expression of genes associated with root development and nitrate transporters, ultimately enhancing both root ...
Dejie Du, Zhaoju Li, Zihao Jiang, Jun Yuan, Xiangyu Zhang, Huanhuan Zhao, Lulu Tian, Yunjie Liu, Renhan Li, Fei He, Xiongtao Li, Wensheng Ke, Lingling Chai, Jie Liu, Mingming Xin, Yingyin Yao, Qixin Sun, Jiewen Xing, Zhongfu Ni   +18 more
wiley   +1 more source

Targeting pseudoknots with Cas13b inhibits porcine epidemic diarrhoea virus replication. [PDF]

J Gen Virol
Han HJ, Yu D, Yu J, Kim J, Do Heo W, Tark D, Kang SM.   +6 more
europepmc   +1 more source

Glutathione-Coated Luminescent Gold Nanoparticles: A Surface Ligand for Minimizing Serum Protein Adsorption

, 2014
Rodrigo D. Vinluan, Jinbin Liu, Chen Zhou, Mengxiao Yu, Shengyang Yang, Amit Kumar, Shasha Sun, Andrew P. Dean, Xiankai Sun, Jie Zheng   +9 more
openalex   +1 more source

Nuclear‐Localized BCKDK Facilitates Homologous Recombination Repair to Support Breast Cancer Progression and Therapy Resistance

Advanced Science, EarlyView.
Under DNA damage, tumor cells rely on efficient DNA repair for survival and therapy resistance. This study has demonstrated that BCKDK localizes to breast cancer cell nuclei, where it binds to and phosphorylates RNF8, thereby blocking ubiquitin‐mediated degradation of RAD51 and enhancing HRR. A selective BCKDK inhibitor synergizes with clinical agents,
Haiying Liu, Jiaqian Feng, Tingting Pan, Pinggen Zhang, Ling Ye, Zetan Jiang, Zilong Zhou, Qiankun Mao, Jian Li, Xinyi Yang, Ping Gao, De Huang, Huafeng Zhang   +12 more
wiley   +1 more source

Maturing conditions of bimetallic nanocomposites as a new factor influencing Au-Ag synergism and impact of Cu(II) and/or Fe(III) on luminescence. [PDF]

R Soc Open Sci
Svačinová V, Pluháček T, Petr M, Siskova K.   +3 more
europepmc   +1 more source