Results 61 to 70 of about 1,644,009 (295)

Validation of flavivirus infectious clones carrying fluorescent markers for antiviral drug screening and replication studies

Frontiers in Microbiology, 2023
Flaviviruses have emerged as major arthropod-transmitted pathogens and represent an increasing public health problem worldwide. High-throughput screening can be facilitated using viruses that easily express detectable marker proteins.
Liubov Cherkashchenko, Liubov Cherkashchenko, Nathalie Gros, Alice Trausch, Aymeric Neyret, Mathilde Hénaut, Gregor Dubois, Matthieu Villeneuve, Christine Chable-Bessia, Sébastien Lyonnais, Andres Merits, Delphine Muriaux, Delphine Muriaux   +12 more
doaj   +1 more source

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

FEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang, Mingqiang Deng, Dongmei He, Diqin Lai, Dongjun Liu, Dengyong Zhu, Zhenhua Zhang, Peng Tang, Chuanman Zhou, Menghui Yin, Xichen Bao   +10 more
wiley   +1 more source

Synthesis and characterization of time-resolved lanthanide (III) luminescent probes for potential detection of melanoma skin cancer [PDF]

, 2017
The focal point of this research is to continue the development of a time-resolved lanthanide (III) luminescent probe that may aid in early detection of melanoma skin cancer. If melanoma cancer is found at an early stage, it can successfully be taken out
NC DOCKS at Western Carolina University, Love, Brian William   +1 more
core  

Highly luminescent TCNQ in melamine [PDF]

, 2023
Optical properties of molecules change drastically as results of interactions with surrounding environments as observed in solutions, clusters and aggrergates. Here we make 7,7,8,8-tetracyanoquinodimethane (TCNQ) highly luminescent by encapsulating it in
Vipin, Mishra, Arthur, Mantel, Hidetsugu, Shiozawa, Peter, Kapusta, Alexander, Prado-Roller   +4 more
core   +1 more source

Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection

FEBS Open Bio, EarlyView.
Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow, Isabel Brandtjen, Yaxin Mo, Melissa Gulley, Louis Osorio, Sagar Kudchodkar, Nandita C. Jhumur, Christine C. Roberts, Lisa K. Denzin, David I. Shreiber, Biju Parekkadan, Hao Lin, Joel N. Maslow   +12 more
wiley   +1 more source

Site-selective ser-hydrolase labelling with a luminescent organometallic NCN-platinum complex [PDF]

, 2010
The synthesis, spectroscopic properties and protein-binding studies of a novel luminescent organometallic NCN-platinum complex are described. The luminescent organometallic complex was linked to a serine hydrolase reactive phosphonate group by means of ...
van Koten, G., Sub Chem Biol & Organic Chem begr 1-6-12, Organic Chemistry and Catalysis, Dijkstra, H.P., Sub Membrane Enzymology begr. 01-06-12, Egmond, M.R., Lemcke, B., Klein Gebbink, R.J.M., Dep Scheikunde, Wieczorek, B., Membrane Enzymology   +10 more
core   +1 more source

A new insight into aggregation structure of organic solids and its relationship to room‐temperature phosphorescence effect

Aggregate
In order to improve the performance of organic luminescent materials, lots of studies have been carried out at the molecular level. However, these materials are mostly applied as solids or aggregates in practical applications, in which the relationship ...
Mingxue Gao, Jia Ren, Yanxiang Gong, Manman Fang, Jie Yang, Zhen Li   +5 more
doaj   +1 more source

Enhancement of intrinsic protein luminescence in nanosized complex

Doklady Biochemistry and Biophysics, 2012
[No abstract available]
Chudinova G.K., Nagovitsyn I.A., Nikitin A.K., Kurilkin V.V., Konov V.I.   +4 more
openaire   +4 more sources

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

Light-Emitting Silicon Nanowires (Si NWs) as a Novel Sensing Platform for SARS-CoV-2 Detection

Proceedings
Silicon nanowires (Si NWs) are considered an outstanding material for several applications. We have realized quantum-confined and room-temperature luminescent Si NWs.
Antonio Alessio Leonardi, Emanuele Luigi Sciuto, Maria José Lo Faro, Barbara Fazio, Maria Giovanna Rizzo, Luca Francioso, Rosaria Anna Picca, Francesco Nastasi, Alessia Irrera, Sabrina Conoci   +9 more
doaj   +1 more source