Results 141 to 150 of about 3,948,840 (323)

A Preventive Approach to Common Diseases of the Lung [PDF]

, 1954
H. Joules
openalex   +1 more source

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

Molecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson, Emma L. Dorward, Kristyn Jurrius, Nathalie Nataren, Markus Tondl, Kay K. Myo Min, Michaelia P. Cockshell, Anahita Fouladzadeh, John Toubia, Mark DeNichilo, Delphine Merino, Claudine S. Bonder   +11 more
wiley   +1 more source

"Embryoma of Lung" [PDF]

, 1952
W. G. Barnard
openalex   +1 more source

Underestimation of lung regions on chest X-ray segmentation masks assessed by comparison with total lung volume evaluated on computed tomography [PDF]

arXiv
Lung mask creation lacks well-defined criteria and standardized guidelines, leading to a high degree of subjectivity between annotators. In this study, we assess the underestimation of lung regions on chest X-ray segmentation masks created according to the current state-of-the-art method, by comparison with total lung volume evaluated on computed ...
arxiv  

MET and NF2 alterations confer primary and early resistance to first‐line alectinib treatment in ALK‐positive non‐small‐cell lung cancer

Molecular Oncology, EarlyView.
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu, Ning Ding, Xiaobo Xu, Yedan Chen, Yong Zhang, Jingwen Liu, Jiebai Zhou, Hairong Bao, Donghui Zhang, Yijun Song, Yang Shao, Yuanlin Song   +11 more
wiley   +1 more source

Chronic Diffuse Interstitial Fibrosis of the Lungs [PDF]

, 1951
A. G. Heppleston
openalex   +1 more source

Mutational landscape determines sensitivity to PD-1 blockade in non–small cell lung cancer

Science, 2015
N. Rizvi, M. Hellmann, A. Snyder, P. Kvistborg, V. Makarov, J. Havel, William Lee, Jianda Yuan, P. Wong, Teresa Ho, Martin L. Miller, N. Rekhtman, A. Moreira, Fawzia Ibrahim, Cameron Bruggeman, Billel Gasmi, R. Zappasodi, Y. Maeda, C. Sander, E. Garon, T. Merghoub, J. Wolchok, T. Schumacher, T. Chan   +23 more
semanticscholar   +1 more source

Improving Lung Cancer Diagnosis and Survival Prediction with Deep Learning and CT Imaging [PDF]

arXiv
Lung cancer is a major cause of cancer-related deaths, and early diagnosis and treatment are crucial for improving patients' survival outcomes. In this paper, we propose to employ convolutional neural networks to model the non-linear relationship between the risk of lung cancer and the lungs' morphology revealed in the CT images.
arxiv  

Ubiquitination of transcription factors in cancer: unveiling therapeutic potential

Molecular Oncology, EarlyView.
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley   +1 more source

REST OF THE INDIVIDUAL LUNG BY POSTURE [PDF]

, 1916
Gerald B. Webb
openalex   +1 more source