Results 131 to 140 of about 2,211,257 (305)

Hsa_circ_0079929 in lung adenocarcinoma and its biological implications in lung adenocarcinoma progression

open access: yesJournal of Cardiothoracic Surgery
This report investigated the expression, prognostic and biological implications of hsa_circ_0079929 in lung adenocarcinoma, which was based on clinical and experimental data.Patients with lung adenocarcinoma were screened and their clinical data and tissues (including cancerous tissues and adjacent normal tissues) were collected.
Yuan Shen, Ruixue Han, Xin Yu, Jing Mao
openaire   +3 more sources

Identification of integrin drug targets for 17 solid tumor types. [PDF]

open access: yes, 2018
Integrins are contributors to remodeling of the extracellular matrix and cell migration. Integrins participate in the assembly of the actin cytoskeleton, regulate growth factor signaling pathways, cell proliferation, and control cell motility.
Arun, Adith S   +2 more
core   +1 more source

Lung: Translocations in Adenocarcinoma [PDF]

open access: yesAtlas of Genetics and Cytogenetics in Oncology and Haematology, 2015
Review on Lung: Translocations in Adenocarcinoma, with data on clinics, and the genes involved.
openaire   +3 more sources

In vivo epigenetic CRISPR screen identifies Asf1a as an immunotherapeutic target in Kras-mutant lung adenocarcinoma.

open access: yesCancer Discovery, 2019
Despite substantial progress in lung cancer immunotherapy, the overall response rate in KRAS-mutant lung adenocarcinoma (ADC) patients remains low. Combining standard immunotherapy with adjuvant approaches that enhance adaptive immune responses-such as ...
Fei Li   +27 more
semanticscholar   +1 more source

Correlations between OCT4 Expression and Clinicopathological Factors 
and Prognosis of Patients with Lung Adenocarcinoma

open access: yesChinese Journal of Lung Cancer, 2013
Background and objective In recent years, cases of lung adenocarcinoma morbidity have consistently grown. OCT4 is the key gene that controls the automatic renewal of stem cells, and regulates the proliferation and differentiation of cancer stem cells ...
Xueyan ZHANG   +5 more
doaj   +1 more source

An Orally Active Galectin-3 Antagonist Inhibits Lung Adenocarcinoma Growth and Augments Response to PD-L1 Blockade.

open access: yesCancer Research, 2019
A combination therapy approach is required to improve tumor immune infiltration and patient response to immune checkpoint inhibitors that target negative regulatory receptors.
Lynda Vuong   +17 more
semanticscholar   +1 more source

Inhibition of NRF1/ABCC1 improves chemosensitivity of human lung adenocarcinoma cell lines to cisplatin [PDF]

open access: yesJichu yixue yu linchuang
Objective To explore the effect of nuclear respiratory factor 1(NRF1) activation of ATP binding cassette transporter C1(ABCC1) transcription on cisplatin resistance in lung adenocarcinoma cells and its potential mechanisms.
CHEN Qingxia, LIANG Yuling, LUO Yalan, NIU Bin
doaj   +1 more source

Wnt1 silences chemokine genes in dendritic cells and induces adaptive immune resistance in lung adenocarcinoma

open access: yesNature Communications, 2019
Lung adenocarcinoma (LUAD)-derived Wnts increase cancer cell proliferative/stemness potential, but whether they impact the immune microenvironment is unknown. Here we show that LUAD cells use paracrine Wnt1 signaling to induce immune resistance. In TCGA,
D. Kerdidani   +14 more
semanticscholar   +1 more source

Diffuse pulmonary infiltrates: A guise of adenocarcinoma

open access: yesRespiratory Medicine Case Reports, 2017
Small and non-small cell lung cancer present in a variety of radiologic and clinical patterns, and have been linked to smoking. Primary adenocarcinoma of the lung has been increasingly recognized in females and nonsmokers, often presenting a diagnostic ...
Mourad Ismail, Raminderjit Sekhon
doaj   +1 more source

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