Results 161 to 170 of about 279,339 (314)

MCM4 as Potential Metastatic Biomarker in Lung Adenocarcinoma. [PDF]

open access: yesDiagnostics (Basel)
Lai HC, Liu JF, Chang TM, Ling TY.
europepmc   +1 more source

A Case of CA19-9 Producing Papillary Adenocarcinoma (Bronchiolo-Alveolar Carcinoma) of the Lung Diagnosed by Open Lung Biopsy.

open access: bronze, 1994
小牟田 清   +9 more
openalex   +2 more sources

Association between Smoking and Tumor Progression in Japanese Women with Adenocarcinoma of the Lung [PDF]

open access: green, 1999
Ikuo Sekine   +7 more
openalex   +1 more source

A Super‐Enhancer‐Driven Transcriptional Regulatory Circuit Underlying Abiraterone Resistance in Castration‐Resistant Prostate Cancer

open access: yesAdvanced Science, EarlyView.
This study identifies a super‐enhancer‐driven transcriptional regulatory circuit comprising BCL6, SMAD3, and NFIB that cooperate to drive cholesterol synthesis via SREBF2/HMGCR/FDFT1 activation and regulate CDK2/CCND3 for cell cycle control. Targeting this circuit with BI‐3802 or downstream inhibitors (Fatostatin/Lovastatin) overcomes abiraterone ...
Liling Jiang   +18 more
wiley   +1 more source

KLF13 promotes ferroptosis and chemosensitivity in lung adenocarcinoma. [PDF]

open access: yesBMC Biol
Shi H   +9 more
europepmc   +1 more source

RPL6 Interacts with HMGCS1 to Stabilize HIF‐1α by Promoting Cholesterol Production in Hepatocellular Carcinoma

open access: yesAdvanced Science, EarlyView.
The study found that RPL6 is frequently upregulated in HCC tissues with extrahepatic metastasis. Elevated RPL6 bound to and increased the stability of HMGCS1 mRNA, thereby enhancing intracellular cholesterol levels. Subsequently, increased cholesterol promotes cancer metastasis in HCC by stabilizing HIF‐1α protein.
Minli Yang   +15 more
wiley   +1 more source

Oral Engineered Extracellular Vesicles Based on Ion Exchange Strategy for Multipronged Management of Wilson's Disease Complicated with Reproductive Dysfunction Therapy

open access: yesAdvanced Science, EarlyView.
This study reports for the first time an oral targeted nanomedicine that conducts ion exchange through engineered Ganoderma‐derived extracellular vesicle, managing both the in‐copper and ex‐copper in a multi‐pronged approach, offering a promising therapeutic strategy for addressing WD with reproductive dysfunction.
Tingting Wang   +12 more
wiley   +1 more source

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