Results 251 to 260 of about 2,251,685 (405)

Synthesis of lantadene analogs with marked in vitro inhibition of lung adenocarcinoma and TNF-α induced nuclear factor-kappa B (NF-κB) activation

, 2014
Monika Monika, Ankesh Sharma, Sharad Kumar Suthar, Vaibhav Aggarwal, Hong Boon Lee, Manu Sharma   +5 more
openalex   +1 more source

Prognostic significance of IMMT expression in surgically‐resected lung adenocarcinoma [PDF]

, 2019
Yasuhiro Hiyoshi, Yuichi Sato, Masaaki Ichinoe, Ryo Nagashio, Daisuke Hagiuda, Makoto Kobayashi, Seiichiro Kusuhara, Satoshi Igawa, Kazu Shiomi, Naoki Goshima, Yoshiki Murakumo, Makoto Saegusa, Yukitoshi Satoh, Noriyuki Masuda, Katsuhiko Naoki   +14 more
openalex   +1 more source

HSP70 Interactome‐Mediated Proteolysis Targeting Chimera (HSP70‐PROTAC) for Ferroptosis‐Driven Cancer Treatment

Advanced Science, EarlyView.
This study reports a novel targeted protein degradation strategy termed “HSP70‐PROTAC” that recruits Hsc70 complex to a target protein for inducing degradation. Among them, GDAz‐3 exhibits effective GPX4 degradation activity via UPS/CMA processes, triggering ferroptosis‐driven anticancer activity in vitro and in vivo.
Jinyun Dong, Yulong Li, Hui Liang, Zumei Wu, Shiqun Wang, Yichao Wang, Jieyu Xu, Yanning Lan, Maohua Cai, Guangzhao Pan, Haiyan Yang, Kai Miao, Zhe‐Sheng Chen, Fangfang Tao, Xuelei Ma, Jiang‐Jiang Qin   +15 more
wiley   +1 more source

Identification and functional characterization of genes associated with lipopolysaccharide in lung adenocarcinoma. [PDF]

BMC Cancer
Zhou S, Gao M, Dong S, Wang M, Xiao H, Shu Y, Wang X.   +6 more
europepmc   +1 more source

A Natural Sweetener‐inducible Genetic Switch Controls Therapeutic Protein Expression in Mammals

Advanced Science, EarlyView.
This study develops a natural sweetener, the psicose‐inducible transgene expression (PURE) system based on an Agrobacterium tumefaciens–derived transcriptional repressor PsiR. The PURE system is highly specific to psicose, being insensitive to other sugars and structurally similar molecules.
Longliang Qiao, Zhihao Wang, Shasha Tang, Yuan Fang, Guiling Yu, Xiaoting Qiu, Lingxue Niu, Tao Yan, Xingwan Liu, Xiaoding Ma, Deqiang Kong, Yang Zhou, Ningzi Guan, Jinzhong Tian, Meiyan Wang, Haifeng Ye, Fengfeng Cai   +16 more
wiley   +1 more source

Loffler endocarditis as an initial manifestation of lung adenocarcinoma: A case report. [PDF]

Medicine (Baltimore)
Yao H, Chen Y, Wu C, Wang Z, Bai F.
europepmc   +1 more source

Prognostic significance of micropapillary pattern and risk factors in patients with resected stage I lung adenocarcinoma and possible benefit of adjuvant therapy: a real-world multicenter study

Jianjie Li, Yujia Chi, Bo Jia, Qiwen Zheng, Minghan Yuan, Jianjun Zhang, A. Zhou, Wei Sun, Yue Yang, Jun Zhao, Tongtong An, Mengling Liu, Minglei Zhuo, Yang Xue, Hanxiao Chen, Jingjing Wang, Xiaoyu Zhai, Yidi Tai, Yuling He, Ling‐Dong Kong, Xumeng Ji, Yiliang Liu, Nan Wu, Ken Onodera, Paul Van Schil, Mathew Thomas, Fan Yang, Ziping Wang   +27 more
openalex   +1 more source

Lung Colloid Adenocarcinoma [PDF]

, 2020
openaire   +1 more source

Mutual Exclusion Analysis Shows that DUSP9 Negatively Regulates PD‐L1 Expression and Acts as a Target to Enhance Anti‐PD‐1 Efficacy

Advanced Science, EarlyView.
A mutually exclusive screening system is established to identify negative regulators of highly plastic genes. Dual specificity phosphatase (DUSP9) is a novel negative regulatory molecule of PD‐L1 by dephosphorylating STAT3, and acts as a target molecule in combination with PD‐1 antibody for tumor immunotherapy and a new clinical biomarker for ...
Yuzhe Hu, Ling Tang, Zheng Kuang, Danyi Huang, Ting Li, Gaofei Yin, Yingyu Chen, Wei Guo, Wenling Han, Pingzhang Wang   +9 more
wiley   +1 more source

Deciphering the Role of ADAMTS6 in the Epithelial-Mesenchymal Transition of Lung Adenocarcinoma Cells. [PDF]

Int J Mol Sci
Odarenko KV, Matveeva AM, Stepanov GA, Zenkova MA, Markov AV.   +4 more
europepmc   +1 more source