Results 81 to 90 of about 2,211,257 (305)

A “triple whammy” in adenocarcinoma lung

Lung India, 2019
Osimertinib (AZD9291), a third-generation epidermal growth factor receptor (EGFR)-tyrosine-kinase inhibitor (TKI), is useful in the treatment of non-small cell lung cancer who show resistance to first-generation EGFR-TKIs and harbor T790M mutation. Acquisition of resistance to osimertinib due to several mechanisms has been reported. We report the first
Ram Babu Sah, Dipti Gothi, Mahismita Patro, Sameer Vaidya   +3 more
openaire   +4 more sources

Gastric cancer is the leading cause of death in Italian adult patients with common variable immunodeficiency [PDF]

, 2018
An increased prevalence of malignant lymphoma and of gastric cancer has been observed in large cohorts of patients with common variable immunodeficiency (CVID), the most frequently symptomatic primary immunodeficiency. Surveillance strategies for cancers
Agostini, Carlo, Cinetto, Francesco, Crescenzi, Ludovica, Milito, Cinzia, Pecoraro, Antonio, Pulvirenti, Federica, Quinti, Isabella, Rizzo, Francesca, Santangeli, Enrico, Spadaro, Giuseppe, Tabolli, Stefano, Valente, Michele   +11 more
core   +3 more sources

Development and validation of an immune‐related prognostic signature in lung adenocarcinoma

Cancer Medicine, 2020
Lung adenocarcinomas (LUAD) is the most common histological subtype of lung cancers. Tumor immune microenvironment (TIME) is involved in tumorigeneses, progressions, and metastases. This study is aimed to develop a robust immune‐related signature of LUAD.
Sijin Sun, W. Guo, Zhen Wang, Xin Wang, Guochao Zhang, Hao Zhang, Renda Li, Yibo Gao, B. Qiu, F. Tan, Yushun Gao, Q. Xue, Shugeng Gao, Jie He   +13 more
semanticscholar   +1 more source

p40 Immunohistochemistry Is an Excellent Marker in Primary Lung Squamous Cell Carcinoma [PDF]

Journal of Pathology and Translational Medicine, 2018
Background Lung cancer is the third most common cancer worldwide. With major advances in the molecular testing of lung cancers and the introduction of targeted therapies, the distinction between adenocarcinoma and squamous cell carcinoma as well as ...
Khairunisa Ahmad Affandi, Nur Maya Sabrina Tizen, Muaatamarulain Mustangin, Reena Rahayu MdReena Rahayu Md Zin   +3 more
doaj   +1 more source

Controversies and challenges in the histologic subtyping of lung adenocarcinoma

Translational Lung Cancer Research, 2020
Lung adenocarcinomas differ in prognosis based on their histologic growth pattern. Adenocarcinoma in situ (AIS) and minimally invasive adenocarcinoma (MIA) both have an excellent prognosis when completely resected, whereas solid and micropapillary ...
K. Butnor
semanticscholar   +1 more source

Rab3B enhances the stabilization of DDX6 to promote lung adenocarcinoma aggressiveness

Molecular Medicine
Background Liver kinase B1 (LKB1) is frequently mutated in lung adenocarcinoma, and its loss contributes to tumor progression. Methods To identify LKB1 downstream genes that promote lung adenocarcinoma aggressiveness, we performed bioinformatical ...
Guodong Yao, Shan Yu, Feng Hou, Zunyu Xiao, Guangqi Li, Xiaobin Ji, Jigang Wang   +6 more
doaj   +1 more source

Expression of ASPM in Lung Adenocarcinoma and Its Relationship with Development and Prognosis

Chinese Journal of Lung Cancer, 2020
Background and objective Previous studies have shown that ASPM is a tumorigenesis associated protein, mutations in ASPM can lead to MCPH. This study mainly explores the relationship between the ASPM expression of lung adenocarcinoma and the development ...
Junjie WANG, Zhenyu HE, Renhui DUAN
doaj   +1 more source

Multi‐kinase framework promotes proliferation and invasion of lung adenocarcinoma through activation of dynamin‐related protein 1

Molecular Oncology, 2021
Recent studies revealed the role of dynamin‐related protein 1 (DRP1), encoded by the DNM1L gene, in regulating the growth of cancer cells of various origins. However, the regulation, function, and clinical significance of DRP1 remain undetermined in lung
Kuei‐Pin Chung, Yen‐Lin Huang, Yi‐Jung Chen, Yi‐Hsiu Juan, Chia‐Lang Hsu, Kiichi Nakahira, Yen‐Tsung Huang, Mong‐Wei Lin, Shang‐Gin Wu, Jin‐Yuan Shih, Yih‐Leong Chang, Chong‐Jen Yu   +11 more
doaj   +1 more source

Lung Adenocarcinoma with Gingival Metastasis

European Journal of Case Reports in Internal Medicine, 2018
Gingival metastasis of lung cancer is uncommon. We report the case of an 82-year-old male smoker admitted to the pulmonology department with right pleural effusion. A chest computed tomography (CT) scan showed an invasive right hilar tumour, adherent to the superior vena cava, pulmonary artery, main right bronchus, mediastinal pleura and pericardium ...
Gargouri, Imen, Hergli, Benzarti Wafa, Aissa, Sana, Kanoun-Belajouza, Samia, Hayouni, Abdelaziz, Garrouche, Abdelhamid, Abdelghani, Ahmed, Benzarti, Mohamed   +7 more
openaire   +5 more sources

Predicting EGFR mutation status in lung adenocarcinoma on computed tomography image using deep learning

European Respiratory Journal, 2019
Epidermal growth factor receptor (EGFR) genotyping is critical for treatment guidelines such as the use of tyrosine kinase inhibitors in lung adenocarcinoma.
Shuo Wang, Jingyun Shi, Z. Ye, D. Dong, Dongdong Yu, Mu Zhou, Y. Liu, O. Gevaert, Kun Wang, Yongbei Zhu, Hongyu Zhou, Zhenyu Liu, Jie Tian   +12 more
semanticscholar   +1 more source