Results 231 to 240 of about 2,054,545 (287)

Pre‐Encoded IFN‐I Sensitivity Exacerbates Memory T Cell Senescence in Solid Tumors

Advanced Science, EarlyView.
Type I interferon (IFN‐I) signaling promotes p21‐dependent cell cycle arrest in senescent tumor‐specific memory T cells, resulting in poor proliferative responses and solid tumor regression during cancer vaccination. Conversely, IFNα/β receptor blockade reinvigorates T cell proliferation to regress solid tumors and is more effective with increasing ...
Andrew Nguyen, Scott R Walsh, Li Deng, Lan Chen, Yonghong Wan   +4 more
wiley   +1 more source

Organized Lung Cancer Screening of Subjects Occupationally Exposed to Lung Carcinogens: The LUng Cancer Screening Occupational exposure Study Entry Findings. [PDF]

JTO Clin Res Rep
Delva F, Gendarme S, Boudet L, Zysman M, Fuhrman C, Brillet PY, Brochard P, Paris C, Bylicki O, Le Denmat V, Loddé B, Belacel M, Abdessemed N, Despagne M, Jaunas K, Lacourt A, Clin B, Gehanno JF, Laurent F, Dournes G, Mathoulin-Pélissier S, Chouaïd C, Pairon JC.   +22 more
europepmc   +1 more source

Interactions of Antibody Drug Conjugate Anti‐Tubulin and Topoisomerase I Inhibitor Payloads with Radiotherapy to Potentiate Immunotherapy

Advanced Science, EarlyView.
Antibody drug conjugates deliver their cytotoxic anti‐tubulin or topoisomerase I inhibitor payloads to tumors through cancer cell receptor targeting. The released drug payloads induce cellular changes that interact with radiotherapy resulting in radiosensitization that improves cancer cell kill and stimulates anti‐tumor immune responses.
Jacqueline Lesperance, Bryan S. Yung, Michael M. Allevato, Marcus M Cheng, Maria F. Camargo, Robert Saddawi‐Konefka, Kanika Dhawan, Ashwyn K. Sharma, Mahsa Mortaja, Sophie Bice, Daniel J. Scanderbeg, Diego Alvarado, Jyoti Mayadev, Ramez N. Eskander, Stephen R. Adams, Pippa F. Cosper, J. Silvio Gutkind, Sunil J. Advani   +17 more
wiley   +1 more source

Clinical Versus Pathologic Staging in Early-Stage Non-Small Cell Lung Cancer Assessed by an Established Lung Cancer Multidisciplinary Meeting. [PDF]

Thorac Cancer
Nolan J, Sather T, Hukins C, Murphy M.
europepmc   +1 more source

Tailoring Vascular‐Immune Homeostasis via Manganese‐DNA Complex‐Armed Immunogenic Extracellular Vesicles for Pancreatic Cancer Immunotherapy

Advanced Science, EarlyView.
This study demonstrates that Mn2⁺–tumor DNA complexes encapsulated in dendritic cell (DC)– derived immunogenic extracellular vesicles (EVDC@Mn‐DNA) act as a DC‐specific cGAS– STING activator. EVDC@Mn‐DNA treatment enhances intratumoral DC activation, improves tumor vascular function, promotes CD8⁺ T cell activity, and suppresses pancreatic tumor growth,
Xue Jiang, Lihuan Shang, Xiaochun Chen, Xiangzhan Kong, Xiaojuan Wang, Linjia Jiang, Huiying Zhao, Yafeng Zhu, Cheng Huang, Shiyi Deng, Rui Zhang, Minghui Wang, Haoming Lin, Ping‐Pui Wong   +13 more
wiley   +1 more source

Lung cancer screening care pathways in community settings: an examination of 3 healthcare systems. [PDF]

Ann Am Thorac Soc
Walsh C, Palazzo L, Hansell L, Louie T, Long S, Brown M, Hippe DS, Coronado GD, Decell K, Leone RJ, Lodhi S, Wysham N, Wernli KJ, Triplette M.   +13 more
europepmc   +1 more source

Engineering T cell therapies for lung cancer. [PDF]

Mol Ther Oncol
Balke-Want H, Keerthi V, Feldman SA.
europepmc   +1 more source

Erratum: Crizotinib Treatment for Lorlatinib-resistant MET-amplified EML4-ALK-fusion Positive Advanced Lung Adenocarcinoma: A Case Report

Chinese Journal of Lung Cancer
Editorial Office of Chinese Journal of Lung Cancer
doaj   +1 more source

The progress of biomarkers detection to lung cancer. [PDF]

Discov Oncol
Qi H, Li F, Peng L, Lin J, Jiang Z.
europepmc   +1 more source