Results 21 to 30 of about 356,670 (302)

Lymphatic function is required prenatally for lung inflation at birth [PDF]

, 2014
Mammals must inflate their lungs and breathe within minutes of birth to survive. A key regulator of neonatal lung inflation is pulmonary surfactant, a lipoprotein complex which increases lung compliance by reducing alveolar surface tension (Morgan, 1971)
Adams, Alders, Aslihan Sen, Atochina-Vasserman, Avery, Bellini, Bland, Bourbon, Celeste M. Nelson, Clark, Compernolle, Couser, David R. Enis, David R. Rawnsley, Guyton, Haddy, Hintz, Hummler, Janér, Jason P. Gleghorn, Jisheng Yang, Kaipainen, Karkkainen, Karkkainen, Kobayashi, Kulkarni, Laurence, Lee, Mark L. Kahn, Martel, Milner, Moessinger, Morgan, Morikawa, Mäkinen, Nogee, Noonan, Patrick, Paul R. Hess, Schnitzer, Sharp, Stephanie Chia, Suresh, Susan H. Guttentag, Tammela, Wang, Wigle, Xi Liu, Yiqing Yang, Zhang, Zhiying Zou, Zoltán Jakus, Zou   +52 more
core   +1 more source

Endothelial toll-like receptor 4 maintains lung integrity via epigenetic suppression of p16INK4a. [PDF]

, 2019
We previously reported that the canonical innate immune receptor toll-like receptor 4 (TLR4) is critical in maintaining lung integrity. However, the molecular mechanisms via which TLR4 mediates its effect remained unclear.
Ardito, Taylor, Hwangbo, Cheol, Kim, So-Jin, Lee, Patty J, Li, Alfred, Min, Jin-Na, Peng, Tien, Sauler, Maor, Shan, Peiying, Zhang, Xuchen, Zhang, Yi   +10 more
core   +1 more source

Effect of hypothermia on lung compliance [PDF]

Thorax, 1970
The changes in pulmonary compliance have been studied under conditions of total body hypothermia. Five groups of sheep were used; two groups were controls—one for the effects of anaesthesia and the other for normothermic biventricular bypass. The third group was cooled using a femoro-femoral arterio-venous shunt to 20°-23° C.
C W, Deal, J C, Warden, I, Monk
openaire   +2 more sources

Prone position: Does it help with acute respiratory distress syndrome (ARDS) requiring extracorporeal membrane oxygenation (ECMO)? [PDF]

, 2017
Introduction: Lung protective ventilation therapy with low tidal volume-high PEEP is the standard treatment for the patients with acute respiratory distress syndrome (ARDS).
Azimzadeh, Nava, Baram, Michael, Cavarocchi, Nicholas C., Hirose, Hitoshi   +3 more
core   +2 more sources

Alterações da função pulmonar após tratamento cirúrgico de cardiopatias congênitas com hiperfluxo pulmonar Changes in pulmonary function after surgical treatment of congenital heart disease with pulmonary hyperflow

Arquivos Brasileiros de Cardiologia, 2008
FUNDAMENTO: Análise das condições pulmonares dos pacientes no pós-operatório de cirurgia cardíaca pediátrica. OBJETIVO: Avaliar o comportamento da complacência pulmonar e resistência da via aérea nos pacientes portadores de cardiopatias congênitas com ...
Lilian Goraieb, Ulisses Alexandre Croti, Suzana Renata Perez Orrico, Omar Yesid Prieto Rincon, Domingo Marcolino Braile   +4 more
doaj   +1 more source

Is airway pressure release ventilation, a better primary mode of post-operative ventilation for adult patients undergoing open heart surgery? A prospective randomised study

Annals of Cardiac Anaesthesia, 2021
Context: Cardiopulmonary bypass (CPB) induced acute lung injury is accounted for most of the post-operative pulmonary dysfunction which leads to decreased compliance and hypoxemia.
V Manjunath, Bhavya G Reddy, S R Prasad
doaj   +1 more source

Deletion of vitamin D receptor leads to premature emphysema/COPD by increased matrix metalloproteinases and lymphoid aggregates formation [PDF]

, 2011
Deficiency of vitamin D is associated with accelerated decline in lung function. Vitamin D is a ligand for nuclear hormone vitamin D receptor (VDR), and upon binding it modulates various cellular functions.
Hwang, Jae-woong, Rahman, Irfan, Sun, Jun, Sundar, Isaac K, Wu, Shaoping   +4 more
core   +1 more source

Trajectories of hypoxemia and pulmonary mechanics of COVID-19 ARDS in the NorthCARDS dataset

BMC Pulmonary Medicine, 2022
Background Understanding heterogeneity seen in patients with COVIDARDS and comparing to non-COVIDARDS may inform tailored treatments. Methods A multidisciplinary team of frontline clinicians and data scientists worked to create the Northwell COVIDARDS ...
Daniel Jafari, Amir Gandomi, Alex Makhnevich, Michael Qiu, Daniel M. Rolston, Eric P. Gottesman, Adey Tsegaye, Paul H. Mayo, Molly E. Stewart, Meng Zhang, Negin Hajizadeh   +10 more
doaj   +1 more source

Alveolar Tissue Fiber and Surfactant Effects on Lung Mechanics—Model Development and Validation on ARDS and IPF Patients

IEEE Open Journal of Engineering in Medicine and Biology, 2021
Goal: Alveolar compliance is a main determinant of lung airflow. The compliance of the alveoli is a function of their tissue fiber elasticity, fiber volume, and surface tension.
Jiayao Yuan, Caitlyn M. Chiofolo, Benjamin J. Czerwin, Nikolaos Karamolegkos, Nicolas W. Chbat   +4 more
doaj   +1 more source

Patterns of recruitment and injury in a heterogeneous airway network model [PDF]

, 2015
In respiratory distress, lung airways become flooded with liquid and may collapse due to surface-tension forces acting on air-liquid interfaces, inhibiting gas exchange.
Cressoni M, Murphy SL, Oliver E. Jensen, Peter S. Stewart, The Acute Respiratory Distress Syndrome Network, Weibel ER   +5 more
core   +2 more sources