Results 21 to 30 of about 192,231 (260)

Is airway pressure release ventilation, a better primary mode of post-operative ventilation for adult patients undergoing open heart surgery? A prospective randomised study

Annals of Cardiac Anaesthesia, 2021
Context: Cardiopulmonary bypass (CPB) induced acute lung injury is accounted for most of the post-operative pulmonary dysfunction which leads to decreased compliance and hypoxemia.
V Manjunath, Bhavya G Reddy, S R Prasad
doaj   +1 more source

Trajectories of hypoxemia and pulmonary mechanics of COVID-19 ARDS in the NorthCARDS dataset

BMC Pulmonary Medicine, 2022
Background Understanding heterogeneity seen in patients with COVIDARDS and comparing to non-COVIDARDS may inform tailored treatments. Methods A multidisciplinary team of frontline clinicians and data scientists worked to create the Northwell COVIDARDS ...
Daniel Jafari, Amir Gandomi, Alex Makhnevich, Michael Qiu, Daniel M. Rolston, Eric P. Gottesman, Adey Tsegaye, Paul H. Mayo, Molly E. Stewart, Meng Zhang, Negin Hajizadeh   +10 more
doaj   +1 more source

Alveolar Tissue Fiber and Surfactant Effects on Lung Mechanics—Model Development and Validation on ARDS and IPF Patients

IEEE Open Journal of Engineering in Medicine and Biology, 2021
Goal: Alveolar compliance is a main determinant of lung airflow. The compliance of the alveoli is a function of their tissue fiber elasticity, fiber volume, and surface tension.
Jiayao Yuan, Caitlyn M. Chiofolo, Benjamin J. Czerwin, Nikolaos Karamolegkos, Nicolas W. Chbat   +4 more
doaj   +1 more source

Sevoflurane improves respiratory mechanics and gas exchange in a case series of infants with severe bronchiolitis‐induced acute respiratory distress syndrome

Clinical Case Reports, 2018
Key Clinical Message This report describes the successful use of a new intervention to improve respiratory mechanics and gas exchange in a relatively homogeneous group of infants with severe bronchiolitis‐induced PARDS after failure of conventional ...
Mirco Nacoti, Jacopo Colombo, Oliviero Fochi, Daniele Bonacina, Francesco Fazzi, Giacomo Bellani, Ezio Bonanomi   +6 more
doaj   +1 more source

Comparison of lung aeration loss in open abdominal oncologic surgeries after ventilation with electrical impedance tomography-guided PEEP versus conventional PEEP: a pilot feasibility study [PDF]

Korean Journal of Anesthesiology
Background Existing literature lacks high-quality evidence regarding the ideal intraoperative positive end-expiratory pressure (PEEP) to minimize postoperative pulmonary complications (PPCs). We hypothesized that applying individualized PEEP derived from
A. R. Karthik, Nishkarsh Gupta, Rakesh Garg, Sachidanand Jee Bharati, M. D. Ray, Vijay Hadda, Sourabh Pahuja, Seema Mishra, Sushma Bhatnagar, Vinod Kumar   +9 more
doaj   +1 more source

The application of chest wall compression in ventilation of acute respiratory distress syndrome patients

Guangxi Yike Daxue xuebao
Acute respiratory distress syndrome (ARDS) is a life-threatening non-cardiogenic pulmonary edema. Despite lung-protective ventilation strategies serving as the cornerstone of ARDS treatment, some patients still fail to effectively alleviate hypoxemia or ...
LIU Yuhua, ZHANG Zhaopei, LIU Xiaoqing, LIU Xuesong   +3 more
doaj   +1 more source

Cardiopulmonary interaction during spontaneous breathing and mechanical ventilation [PDF]

Exploration of Cardiology
Cardiopulmonary interaction is a fundamental physiological process during spontaneous breathing, but it is profoundly altered in critically ill patients receiving mechanical ventilation (MV). Positive-pressure ventilation modifies intrathoracic, pleural,
Angel Benjamin Rojas, Susana Vanoni, Carla Gobbi, Juan Carlos Vergottini   +3 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Precision-Controlled Bionic Lung Simulator for Dynamic Respiration Simulation

Bioengineering
Mechanical ventilation is indispensable for patients with severe respiratory conditions, and high-fidelity lung simulators play a pivotal role in ventilator testing, clinical training, and respiratory research.
Rong-Heng Zhao, Shuai Ren, Yan Shi, Mao-Lin Cai, Tao Wang, Zu-Jin Luo   +5 more
doaj   +1 more source