Lung Deposition of Surfactant Delivered via a Dedicated Laryngeal Mask Airway in Piglets [PDF]
Pharmaceutics, 2021 It is unknown if the lung deposition of surfactant administered via a catheter placed through a laryngeal mask airway (LMA) is equivalent to that obtained by bolus instillation through an endotracheal tube.
Anders Nord +9 more
doaj +2 more sources
Lung Deposition and Inspiratory Flow Rate in Patients with Chronic Obstructive Pulmonary Disease Using Different Inhalation Devices: A Systematic Literature Review and Expert Opinion [PDF]
International Journal of COPD, 2021 Adolfo Baloira,1 Araceli Abad,2 Antonia Fuster,3 Juan Luis García Rivero,4 Patricia García-Sidro,5 Eduardo Márquez-Martín,6,7 Marta Palop,8 Néstor Soler,9 JL Velasco,10 Fernando González-Torralba11 1Complejo ...
Baloira A +9 more
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An experimental study on lung deposition of inhaled 2 μm particles in relation to lung characteristics and deposition models [PDF]
Particle and Fibre Toxicology, 2023 Background The understanding of inhaled particle respiratory tract deposition is a key link to understand the health effects of particles or the efficiency for medical drug delivery via the lung.
Jenny Rissler +5 more
doaj +2 more sources
Lung Deposition and Pharmacokinetics of Nebulized Cyclosporine in Lung Transplant Patients [PDF]
Journal of Aerosol Medicine and Pulmonary Drug Delivery, 2014 Inhaled cyclosporine (CsA) is being investigated as a prophylaxis for lung transplant rejection. Lung deposition and systemic exposure of nebulized CsA in lung transplant patients was evaluated as part of the Phase 3 cyclosporine inhalation solution (CIS) trial (CYCLIST).Ten patients received 300 mg of CIS (62.5 mg/mL CsA in propylene glycol) admixed ...
T E, Corcoran +4 more
openaire +3 more sources
Quantitative Imaging of Regional Aerosol Deposition, Lung Ventilation and Morphology by Synchrotron Radiation CT [PDF]
Scientific Reports, 2018 To understand the determinants of inhaled aerosol particle distribution and targeting in the lung, knowledge of regional deposition, lung morphology and regional ventilation, is crucial.
L. Porra +11 more
doaj +6 more sources
FIDEPOC: Consensus on Inspiratory Flow and Lung Deposition as Key Decision Factors in COPD Inhaled Therapy. [PDF]
Int J Chron Obstruct Pulmon Dis, 2022 González-Torralba F +9 more
europepmc +3 more sources
Administration of Bacteriophages via Nebulization during Mechanical Ventilation: In Vitro Study and Lung Deposition in Macaques. [PDF]
Viruses, 2023 Le Guellec S +15 more
europepmc +3 more sources
Pulmonary immunization: deposition site is of minor relevance for influenza vaccination but deep lung deposition is crucial for hepatitis B vaccination [PDF]
Acta Pharmaceutica Sinica B, 2019 Vaccination via the pulmonary route could be an attractive alternative to parenteral administration. Research towards the best site of antigen deposition within the lungs to induce optimal immune responses has conflicting results which might be dependent
Jasmine Tomar +7 more
doaj +2 more sources
Modelled lung deposition and retention of welding fume particles in occupational scenarios: a comparison to doses used in vitro. [PDF]
Arch Toxicol, 2022 McCarrick S, Karlsson HL, Carlander U.
europepmc +3 more sources
Lobar evenness of deposition/retention in rat lungs of inhaled silver nanoparticles: an approach for reducing animal use while maximizing endpoints [PDF]
Particle and Fibre Toxicology, 2019 Background Information on particle deposition, retention and clearance are important for the evaluation of the risk of inhaled nanomaterials to human health.
Jung Duck Park +11 more
doaj +2 more sources