Results 31 to 40 of about 1,756,909 (330)

A Rapid Fluorescence Method for In Vivo Quantitation of Lung Deposition of a Nebulized Drug: Multiple Uses for Advancing Aerosolized Drug Development and Specific Insight Regarding Aerosolized Vitamin A for Preventing Bronchopulmonary Dysplasia. [PDF]

Methods Protoc
Gelfand CA, Wang Y, Chandan G, Liu J, Madrigal S, Sakurai R, Yu C, Guerra C, Segal R, Rehan VK.   +9 more
europepmc   +3 more sources

Numerical Simulation of Particle Motions in Cascade Impactor and Human Respiratory System [PDF]

MATEC Web of Conferences, 2021
Dry powder inhalations (DPIs) have gathered attention as a treatment for respiratory diseases due to the large effective absorption area in a human lung. A cascade impactor is generally used to investigate the inhalation performance of DPIs.
Ohsaki Shuji, Mitani Ryosuke, Fujiwara Saki, Nakamura Hideya, Watano Satoru   +4 more
doaj   +1 more source

A Compartment-Based Mathematical Model for Studying Convective Aerosol Transport in Newborns Receiving Nebulized Drugs during Noninvasive Respiratory Support

Pharmaceutics, 2020
Nebulization could be a valuable solution to administer drugs to neonates receiving noninvasive respiratory support. Small and irregular tidal volumes and air leaks at the patient interface, which are specific characteristics of this patient population ...
Francesco Tarantini, Ilaria Milesi, Xabier Murgia, Federico Bianco, Raffaele L. Dellacà   +4 more
doaj   +1 more source

In Silico Lung Deposition Profiles of Three Single-Inhaler Triple Therapies in Patients with COPD Using Functional Respiratory Imaging. [PDF]

Int J Chron Obstruct Pulmon Dis
Singh D, Roche N, Wu L, Sadafi H, De Backer J, Monshi Tousi N, Marshall J.   +6 more
europepmc   +3 more sources

Quantification of collagen and proteoglycan deposition in a murine model of airway remodelling [PDF]

, 2005
Background: Sub- epithelial extracellular matrix deposition is a feature of asthmatic airway remodelling associated with severity of disease, decline in lung function and airway hyperresponsiveness.
Reinhardt Alistair K, Robin J McAnulty, Reinhardt, AK, McAnulty Robin J, Geoffrey J Laurent, Laurent, GJ, Laurent Geoffrey J, Bottoms, SE, Bottoms Stephen E, McAnulty, RJ, Stephen E Bottoms, Alistair K Reinhardt   +11 more
core   +2 more sources

Evaluation of a Novel Dry Powder Surfactant Aerosol Delivery System for Use in Premature Infants Supported with Bubble CPAP

Pharmaceutics, 2023
Aerosolized lung surfactant therapy during nasal continuous positive airway pressure (CPAP) support avoids intubation but is highly complex, with reported poor nebulizer efficiency and low pulmonary deposition.
Robert M. DiBlasi, Coral N. Crandall, Rebecca J. Engberg, Kunal Bijlani, Dolena Ledee, Masaki Kajimoto, Frans J. Walther   +6 more
doaj   +1 more source

Regional Inhaled Deposited Dose of Indoor Combustion-Generated Aerosols in Jordanian Urban Homes

Atmosphere, 2020
Indoor combustion processes associated with cooking, heating, and smoking are a major source of aerosols in Jordanian dwellings. To evaluate human exposure to combustion-generated aerosols in Jordanian indoor environments, regional inhaled deposited dose
Tareq Hussein, Brandon E. Boor, Jakob Löndahl   +2 more
doaj   +1 more source

Lung Deposition and Inspiratory Flow Rate in Patients with Chronic Obstructive Pulmonary Disease Using Different Inhalation Devices: A Systematic Literature Review and Expert Opinion [Corrigendum]

International Journal of COPD, 2021
Baloira A, Abad A, Fuster A, et al. Int J Chron Obstruct Pulmon Dis. 2021;16:1021–1033. Page 1026, left column, fourth paragraph, the text “Inhaler devices are many times classified as low- (30 L/min or below), medium– (~30–60 L ...
Baloira A, Abad A, Fuster A, García Rivero JL, García-Sidro P, Márquez-Martín E, Palop M, Soler N, Velasco JL, González-Torralba F   +9 more
doaj  

Pulmonary drug delivery strategies: A concise, systematic review

Lung India, 2012
Because of limitations associated with the conventional treatment of various chronic diseases a growing attention has been given to the development of targeted drug delivery systems. Pulmonary route of drug delivery gaining much importance in the present
J S Patil, S Sarasija
doaj   +1 more source

The avian lung-associated immune system [PDF]

, 2006
The lung is a major target organ for numerous viral and bacterial diseases of poultry. To control this constant threat birds have developed a highly organized lung-associated immune system.
Reese, Sven, Dalamani, Grammatia, Kaspers, Bernd, Sven Reese, Grammatia Dalamani, Bernd Kaspers   +5 more
core   +1 more source