Results 181 to 190 of about 1,756,909 (330)

Deposition of inhaled aerosols in the human lung: From infancy to adulthood

Chantal Darquenne
openalex   +1 more source

A Decoy‐Receptor‐Armed Biomimetic Nanotherapeutic With Inherent Tropism for Conserved Pathogenic Macrophages for Treating Osteoarthritis and Intervertebral Disc Degeneration

Advanced Science, EarlyView.
A biomimetic doppelgänger nanosystem neutralizes extracellular inflammatory cytokines and silences intracellular pyroptosis, reprogramming pathogenic macrophages to attenuate both joint and spine degeneration. ABSTRACT Osteoarthritis (OA) and intervertebral disc degeneration (IVDD) are debilitating musculoskeletal disorders driven by shared ...
Fudong Li, Bin Zhang, Zhiqiu Zhang, Bing Zheng, Linhui Han, Chen Yan, Jialin Li, Kaiqiang Sun, Tianyi Zhao, Jiangang Shi   +9 more
wiley   +1 more source

Household wood smoke exposure, lung black carbon deposition, and genomic instability in U.S. Mountain West Residents

Yue Feng, Chelin Hu, Cassie Rowe, Wei-Chung Su, E. Morales Carrasco, Batel Blechter, Tamar Ginossar, Akshay Sood, Changjian Feng, Nathaniel Rothman, Yiliang Zhu, Kristen McHenry, Zeina H Jaffar, Xiaozhong Yu, Hahn, Micah, committee member, Qing Lan B, Shuguang Leng   +16 more
openalex   +1 more source

Carrier‐Free Berberine/Nitidine Chloride Self‐Assembled Nanoparticles Induce Ferroptosis to Overcome Bortezomib Resistance in Multiple Myeloma

Advanced Science, EarlyView.
A schematic illustrating the fabrication process and ferroptosis‐mediated therapeutic mechanism of carrier‐free self‐assembled BBR/NC‐SAPs for overcoming bortezomib resistance in multiple myeloma. ABSTRACT Therapeutic relapse driven by bortezomib resistance represents a formidable clinical barrier in the management of multiple myeloma (MM).
Yiwen Lv, Shuang Liu, Hong Wu, Guiluan Li, Ying Rong, Guangchao Li, Yangmin Zhu, Qi Zhong, Ruiming Ou, Huijuan Shen, Zhi Liu, Jing Huang, Zhenwei Wang, Pei Lin, Qing Zhang, Guopan Yu, Zhao Yin   +16 more
wiley   +1 more source

Effect of Nebulizer Breath-Guiding on Breathing Patterns and Lung Deposition

Benjamin Heine, Uwe Schuschnig, Jakob Richter, Andreas Liebl, Lea Botermann, Gesa Bräunlich, Nicolas Schwenck, Maximilian J. Grill, Michael Hahn   +8 more
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Iron‐Tannic Acid Hydrogel Mediated Mild Photothermal Therapy Combined With Ferroptosis Enhances Anti‐Tumor Immunity in Colorectal Cancer

Advanced Science, EarlyView.
An injectable gelatin‐based tannic acid–iron hydrogel with mild photothermal therapy could not only induce immunogenic cell death, but also elicit ferroptosis of both tumor cells and tumor‐associated macrophages, resulting in DC maturation, T‐cell infiltration and down‐regulation of ferroptosis‐sensitive M2‐type TAMs levels.
Yuan Zhu, Xi Yu, Tao Wang, Wanyi Liu, Chang Lu, Jiani Zhong, Yujie He, Wei Li, Kunxi Zhang, Peihao Yin, Zeting Yuan   +10 more
wiley   +1 more source

Evaluation of analytical particle deposition models against experimental mouse lung data

M. Puig, Nicolas Molinari
openalex   +2 more sources

Transport and deposition of pharmaceutical aerosols in a helium–oxygen mixture in a CT-based nose-to-lung respiratory tract [PDF]

Xinlei Huang, Akshoy Ranjan Paul, Prashanta Kumar Mandal, Suvash C. Saha   +3 more
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Maximizing Deep Lung Deposition in Healthy and Fibrotic Subjects During Jet Nebulization. [PDF]

J Aerosol Med Pulm Drug Deliv, 2020
Samuel J, Smaldone GC.
europepmc   +1 more source

Dual‐Targeting Biomimetic Nanozymes Loaded Microneedle Patch Promotes Scarless Wound Healing Through Anti‐Inflammatory and Anti‐Fibrotic Effects

Advanced Science, EarlyView.
This study developed a dual‐targeting biomimetic nanozyme hybrid system (Cu‐CeO2@ABs‐FTP) and integrated it with HAMA hydrogel to fabricate a microneedle patch (CAF@MN). The patch promotes fibroblast‐mediated wound repair, targets macrophages to induce M2 polarization, and targets myofibroblasts to exert anti‐fibrotic effects, thereby enabling rapid ...
Hongyi Zhang, Jinwei Li, Shan Hua, Shengming Wu, Chenlong He, Yuan Zhu, Ming Yin, Han Zhou, Huawei Liu, Chika Hasegawa, Jun Lyu, Keyue Xiao, Hua Jiang, Yilong Wang, Yuxin Qian   +14 more
wiley   +1 more source