Results 201 to 210 of about 1,756,909 (330)

Engineered Cyanobacteria‐Hydrogel Microecological System for Oxygen Reprogramming Synergizes Immunomodulation With Anabolism in Osteoarthritis Therapy

Advanced Science, EarlyView.
An injectable cyanobacteria‐laden hydrogel enables light‐dependent oxygen metabolism engineering for osteoarthritis therapy. Photosynthetic oxygen release under red light irradiation suppresses synovial inflammation via HIF‐1α inhibition and M2 macrophage polarization, while respiratory oxygen consumption in darkness stabilizes chondrocyte HIF‐1α to ...
Lerong Yang, Chong Shen, Hongjun Huang, Siyi Liu, Zeyu Huang, Licheng Xi, Huan Cao, Li Zheng, Zainen Qin   +8 more
wiley   +1 more source

Application of artificial intelligence in quantifying lung deposition dose of black carbon in people with exposure to ambient combustion particles. [PDF]

J Expo Sci Environ Epidemiol
Jiang M, Hu CJ, Rowe CL, Kang H, Gong X, Dagucon CP, Wang J, Lin Y, Sood A, Guo Y, Zhu Y, Alexis NE, Gilliland FD, Belinsky SA, Yu X, Leng S.   +15 more
europepmc   +1 more source

Erratum: Lung Deposition and Inspiratory Flow Rate in Patients with Chronic Obstructive Pulmonary Disease Using Different Inhalation Devices: A Systematic Literature Review and Expert Opinion [Corrigendum]. [PDF]

Int J Chron Obstruct Pulmon Dis, 2021
europepmc   +1 more source

Real-time single-particle imaging of functional lungs reveals mosaic-like patterns of aerosol deposition in alveoli

Gabrielle N. Grifno, Han Ali Kahvecioglu, Robert LeBourdais, Victoria Travnik, Rohin Banerji, Winita Wangsrikhun, Linzheng Shi, Suleyman B. Bozal, H Suh, Ahmed Raslan, Athanasios Batgidis, Byungjun Kang, Feiyang Deng, Caleb J. Dalton, Andrew Tsao, Lauren Castle, Kathryn Regan, Abdulrahman Kobayter, M. Vannini, Mohammad Rashidian, Liang Hao, Giovanni Ligresti, Joseph P. Mizgerd, P. Worth Longest, Michael Hindle, W. Mark Saltzman, James P. Butler, Bélâ Suki, Hadi Tavakoli Nia   +28 more
openalex   +1 more source

Phase Separation of TRIM21 Modulates PTPN14 Stability to Drive Flow‐Dependent Endothelial Activation and Atherogenesis

Advanced Science, EarlyView.
Disturbed flow promotes the formation of TRIM21‐rich biomolecular droplets, which concentrate TRIM21 and PTPN14 and facilitate their SPRY‐FERM interaction (illustrated by the TRIM21 D355‐PTPN14 R132 salt bridge). This condensate‐driven proximity enables TRIM21 to catalyze K48‐linked polyubiquitination of PTPN14 at lysine 956, leading to proteasome ...
Xue He, Qiannan Ma, Xue Wang, Jiaxu Mang, Chufeng Li, Bingjun Wu, Liu Yao, Yequn Chen, Qiankun Bao, Yi Zhu, Jinlong He   +10 more
wiley   +1 more source

Formation, not degradation: the matrix-deposition axis of fibrotic lung is molecularly decoupled from forced vital capacity

Delfin Reyes
openalex   +1 more source

One‐Step Immobilized Phage Depolymerase Coatings for Catheter‐Related Bloodstream Infections

Advanced Science, EarlyView.
Catheter‐related bloodstream infections (CRBSI) caused by drug‐resistant Gram‐negative bacteria remain a major clinical challenge. Here, a polydopamine‐assisted depolymerase coating degrades bacterial capsules and restores serum‐mediated killing, effectively suppressing biofilms and reducing bacterial burden in vitro, ex vivo, and in vivo, presenting a
Lingkai Dong, Xingjin Li, Tao Hu, Qianqian Lu, Xiaoxu Zhang, Xi Chen, Yifan Luo, Zhong Zuo, Ronald Man Yeung Wong, Miao Xu, Tiancong Zhao, Sharon Shui Yee Leung   +11 more
wiley   +1 more source

Lung deposition patterns of MWCNT vary with degree of carboxylation. [PDF]

Nanotoxicology, 2019
Holian A, Hamilton RF, Wu Z, Deb S, Trout KL, Wang Z, Bhargava R, Mitra S.   +7 more
europepmc   +1 more source

Evaluation of analytical particle deposition models against experimental mouse lung data — reproduction code

M. Puig
openalex   +1 more source

p300‐Mediated H3K18 Lactylation Drives Radiation‐Induced Pulmonary Fibrosis via VIRMA‐Dependent m6A Modification of GATA3

Advanced Science, EarlyView.
Radiation triggers glycolytic reprogramming in alveolar epithelial type II cells, causing pathological lactate accumulation. This metabolic stress drives p300‐mediated H3K18 lactylation at the VIRMA promoter, activating transcription. Elevated VIRMA enriches m6A on GATA3 mRNA, which YTHDF1 stabilizes, ultimately driving epithelial–mesenchymal ...
Junxuan Yi, Mingwei Wang, Duo Yu, Mingqi Zhao, Xinyan Wang, Shiqi Li, Xiaowen Han, Wei Wei, Shunzi Jin   +8 more
wiley   +1 more source