Results 41 to 50 of about 269,803 (346)
Elevated PAI-1 is associated with poor clinical outcomes in pediatric patients with acute lung injury. [PDF]
, 2009 PurposeDeposition of fibrin in the alveolar space is a hallmark of acute lung injury (ALI). Plasminogen activator inhibitor-1 (PAI-1) is an antifibrinolytic agent that is activated during inflammation. Increased plasma and pulmonary edema fluid levels of
Brady, Sandra +4 more
core +2 more sources
AtmosphereAirborne particulate matter is a major pollutant globally due to its impact on atmospheric processes and human health. Depending on their aerodynamic size, particles can penetrate the respiratory system, with ultrafine particles (UFPs) reaching the ...
Fabian L. Moreno Camacho +6 more
doaj +1 more source
KONA Powder and Particle Journal, 2017 The paper discusses essential engineering challenges related to the application of powder medicines for pulmonary delivery as inhaled aerosol. Starting from a physically based description of the complexity of aerosol dynamics inside the respiratory ...
Tomasz R. Sosnowski
doaj +1 more source
FACTORS THAT AFFECT THE LUNG DEPOSITION [PDF]
International Journal of Modern Physics: Conference Series, 2013 The lung is an external organ forming the site of unwanted material or particles. In order to protect it, the airways have to be highly effective filters and if the particle deposit they need to be cleared. Inhaled particles can cause a variety of diseases. There are various factors on which the prediction of depositing particles depends, such as age,
SHWETA SANKHALA +3 more
openaire +1 more source
Particle and Fibre Toxicology, 2023 Background Quantifying the dose and distribution of tobacco smoke in the respiratory system is critical for understanding its toxicity, addiction potential, and health impacts.
Kaisen Lin +6 more
doaj +1 more source
Increased expression of 5-hydroxytryptamine(2A/B) receptors in idiopathic pulmonary fibrosis: a rationale for therapeutic intervention [PDF]
, 2010 Background Idiopathic pulmonary fibrosis (IPF) has a poor prognosis and limited responsiveness to available treatments. It is characterised by epithelial cell injury, fibroblast activation and proliferation and extracellular matrix deposition ...
Amarie, Oana Veronica +8 more
core +1 more source
Control of Collagen Deposition in Mammalian Lung
Experimental Biology and Medicine, 1995 This review considers the mechanisms controlling collagen deposition in mammalian lung in five different states: normal development, fibrosis, erosion, pneumonectomy, and the steady state. Deposition is the net result of positive and negative processes.
R S, Bienkowski, M G, Gotkin
openaire +2 more sources
In vitro release and in vivo study of quercetin-loaded alginate-kappa carrageenan pulmospheres
Journal of Advanced Pharmaceutical Technology & ResearchSome antituberculosis drugs were reported to have adverse effects. The study investigates the use of quercetin pulmospheres as an alternative to traditional antituberculosis drugs.
Dewi Melani Hariyadi +5 more
doaj +1 more source
Regional Inhaled Deposited Dose of Urban Aerosols in an Eastern Mediterranean City
Atmosphere, 2019 We calculated the regional deposited dose of inhaled particulate matter based on number/mass concentrations in Amman, Jordan. The dose rate was the highest during exercising but was generally lower for females compared to males.
Tareq Hussein +5 more
doaj +1 more source
Dual antibiotherapy of tuberculosis mediated by inhalable locust bean gum microparticles [PDF]
, 2017 Despite the existence of effective oral therapy, tuberculosis remains a deadly pathology, namely because of bacterial resistance and incompliance with treatments.
Alves, Ana D. +7 more
core +1 more source