Results 111 to 120 of about 637,902 (343)
Animal Models and Experimental Medicine, EarlyView.In an ethanol (EtOH)‐treated mouse model, increases in the NLRP3 inflammasome proteins, PC degeneration, and motor coordination disorders were observed. DIP suppressed the NLRP3‐ASC‐caspase‐1 signaling pathway, and alleviated the motor deficits and cerebellar pathological changes in chronic EtOH‐treated mice.
Jian Zhang +5 more
wiley +1 more source
Burden of Fungal Infections in Colombia
Journal of Fungi, 2018 Data with respect to the epidemiological situation of fungal diseases in Colombia is scarce. Thus, the aim of this study is to estimate the burden of fungal infections.
Carlos Arturo Alvarez-Moreno +2 more
doaj +1 more source
Inception-Based Network and Multi-Spectrogram Ensemble Applied For Predicting Respiratory Anomalies and Lung Diseases [PDF]
arXiv, 2020 This paper presents an inception-based deep neural network for detecting lung diseases using respiratory sound input. Recordings of respiratory sound collected from patients are firstly transformed into spectrograms where both spectral and temporal information are well presented, referred to as front-end feature extraction.
arxiv
PC945, a Novel Inhaled Antifungal Agent, for the Treatment of Respiratory Fungal Infections
Journal of Fungi, 2020 Disease due to pulmonary Aspergillus infection remains a significant unmet need, particularly in immunocompromised patients, patients in critical care and those with underlying chronic lung diseases. To date, treatment using inhaled antifungal agents has
A. Murray +7 more
semanticscholar +1 more source
Allergic bronchopulmonary aspergillosis: diagnostic and treatment challenges [PDF]
, 2016 Allergic bronchopulmonary aspergillosis (ABPA) is a pulmonary disorder, occurring mostly in asthmatic and cystic fibrosis patients, caused by an abnormal T-helper 2 lymphocyte response of the host to Aspergillus fumigatus antigens.
CINICOLA, BIANCA LAURA +3 more
core +1 more source
Arthritis &Rheumatology, EarlyView.Objective The objective of this study was to investigate the effect of prophylactic trimethoprim‐sulfamethoxazole (TMP‐SMX) on the incidence of serious infections in patients with antineutrophil cytoplasmic antibody–associated vasculitis (AAV). Methods This multicenter cohort study was designed to emulate a target trial that studied 296 patients with ...
Yun Kyu Kim +7 more
wiley +1 more source
iScience, 2023 Summary: Fungi cause various forms of invasive fungal disease (IFD), and fungal sensitization can contribute to the development of asthma, asthma severity, and other hypersensitivity diseases, such as atopic dermatitis (AD). In this study, we introduce a
Huifang Liu +8 more
doaj
Anti-Aspergillus Activities of the Respiratory Epithelium in Health and Disease
Journal of Fungi, 2018 Respiratory epithelia fulfil multiple roles beyond that of gaseous exchange, also acting as primary custodians of lung sterility and inflammatory homeostasis. Inhaled fungal spores pose a continual antigenic, and potentially pathogenic, challenge to lung
Margherita Bertuzzi +6 more
doaj +1 more source
Role of unfolded proteins in lung disease
Thorax, 2020 The lungs are exposed to a range of environmental toxins (including cigarette smoke, air pollution, asbestos) and pathogens (bacterial, viral and fungal), and most respiratory diseases are associated with local or systemic hypoxia.
Kirsty L. Bradley +4 more
semanticscholar +1 more source
Biotechnology and Applied Biochemistry, EarlyView.Abstract Over the past 10 years, nanotechnology has emerged as a very promising technique for a wide range of biomedical applications. Green synthesized metal and metal oxide nanoparticles (NPs) are cheap, easy to produce in large quantities, and safe for the environment.
Kaan Şendal +6 more
wiley +1 more source