Results 161 to 170 of about 3,149,992 (309)

Efficacy of Antimicrobial Silver‐Plated Dressings Compared to Usual Care in Preventing Left Ventricular Assist Device Driveline Infections

open access: yesArtificial Organs, EarlyView.
Integrating silver‐plated wound dressings into DLES care presents a safe and effective strategy for DLI prevention. Key findings include a 100% infection‐free rate in the Silverlon group, no NPWT and hospital readmission in the Silverlon group, and no severe DESTINE stages (3, 4) in the Silverlon group.
Barbara Veiter   +9 more
wiley   +1 more source

Prevention and Management of Driveline Infections in Ventricular Assist Device Patients: The DESTINE 2.0 Staging Proposal and Expert Recommendations

open access: yesArtificial Organs, EarlyView.
DESTINE 2.0 decision flowchart: stage‐based assessment and management of driveline exit‐site disorders. The flowchart provides a simplified decision‐support tool for the stage‐based evaluation and management of driveline exit‐site disorders in LVAD patients, intended as a practical complement to the staging pyramid (Figre 2) and the detailed staging ...
Alexander M. Bernhardt   +7 more
wiley   +1 more source

Diagnostic performance of panfungal PCR on tissue specimens for the diagnosis of invasive fungal diseases: a systematic review and meta-analysis of the Fungal PCR Initiative (FPCRI). [PDF]

open access: yesJ Clin Microbiol
Filippidis P   +27 more
europepmc   +1 more source

Frequency, Burden and Pathogens of Acute Respiratory Illness in Very Preterm Infants During Infancy

open access: yesActa Paediatrica, EarlyView.
ABSTRACT Aim To describe the frequency, burden, and pathogen profile of acute respiratory illnesses (ARIs) in very preterm infants during the first year after neonatal intensive care unit (NICU) discharge. Methods Very preterm infants were followed prospectively (August 2015–January 2017) with monthly assessments of symptoms, medication use, and ...
Patricia De Gouveia Belinelo   +9 more
wiley   +1 more source

Covalent drug discovery: Progress against key targets, emerging strategies and lessons learnt

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Covalent drug discovery is currently experiencing a boom in industrial and academic interest. To date, at least 75 covalent drugs have received regulatory approval, targeting both traditional target classes and more challenging proteins for which other approaches failed. In many cases, unique aspects of covalent targeting are essential for the
Charles P. Brown   +2 more
wiley   +1 more source

COVID-19-Associated Fungal Co-Infections: Pathogenesis, Diagnostics, Biomarkers, and Therapeutic Strategies. [PDF]

open access: yesJ Clin Med
Choudhury S   +10 more
europepmc   +1 more source

Advances in Spatial Heterogeneity and Cellular Localization Specificity of Intratumoral Bacteria

open access: yesCancer Science, EarlyView.
Spatial localization of intratumoral bacteria governs their functional roles in tumor progression, metastasis, and treatment responses, with guiding significance for clinical management, as reviewed across three spatial paradigms. ABSTRACT Bacteria in tumors are increasingly recognized to be a part of the tumor microenvironment and their biological ...
Minlan Ren   +11 more
wiley   +1 more source

Unmasking Iododerma: A Distinctive Histopathologic Pattern of Neutrophil‐Rich Dermatosis With Haloed Cryptococcoid Bodies in the Setting of Hydralazine Exposure and Autoimmune Serologic Abnormalities

open access: yesJournal of Cutaneous Pathology, EarlyView.
ABSTRACT Cutaneous iododerma is a rare adverse reaction to iodine‐containing compounds that may clinically and histopathologically mimic infection, vasculitis, malignancy, and other neutrophilic dermatoses. Although most commonly associated with iodinated contrast exposure, a variety of predisposing factors and potential associations have been reported,
Volha Lenskaya   +4 more
wiley   +1 more source

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