Results 141 to 150 of about 113,160 (301)

Extracellular matrix and proteolysis: mechanisms driving irreversible changes and shaping cell behavior

open access: yesThe FEBS Journal, EarlyView.
Irreversible ECM proteolysis by remodeling enzymes shapes development, homeostasis, and disease. ECM‐degrading proteases display cell specificity and are governed by shared mechanisms, exhibiting functional redundancy in generating matrikines, growth factors, and cytokines.
Inna Solomonov, Orit Kollet, Irit Sagi
wiley   +1 more source

Targeting the microbiota‐miRNA‐protease axis: A new therapeutic avenue in melanoma

open access: yesThe FEBS Journal, EarlyView.
Modulation of extracellular matrix (ECM) turnover is central to melanoma progression and metastasis, driven largely by ECM proteases. This review highlights the epigenetic regulation of ECM proteases by microRNAs and their roles in melanoma growth, invasion, and immune modulation.
Elias N. Katsoulieris   +2 more
wiley   +1 more source

Comparative Prognosis of Fungal Balls Versus Invasive Pulmonary Mucormycosis

open access: yesInfection and Drug Resistance
Jiayu Wang,1– 4 Naishu Xie,1– 4 Rui Zhao,1– 4 Huihui Zeng,1– 4 Yan Chen1– 4 1Department of Pulmonary and Critical Care Medicine, The Second Xiangya Hospital, Central South University, Changsha, Hunan, People’s Republic of China; 2Research Unit of ...
Wang J, Xie N, Zhao R, Zeng H, Chen Y
doaj  

Associations Between Oral Health Related Outcomes and Electronic Cigarette Use in Young People: A Scoping Review

open access: yesInternational Journal of Paediatric Dentistry, EarlyView.
ABSTRACT Background Vaping is prevalent among youth, but its effects on oral health remain poorly understood. Exposure to harmful chemicals and nicotine during this critical developmental period raises concerns for long‐term oral health impacts. Aim This scoping review synthesizes available evidence regarding oral health related outcomes of e‐cigarette
Jessica Tran   +2 more
wiley   +1 more source

An intricate pulmonary infection in a patient with T-cell Acute Lymphoblastic Leukemia

open access: yesMediterranean Journal of Hematology and Infectious Diseases, 2014
Non-albicans Candida (NAC) is rarely isolated from specimens. Here, we report a case of pulmonary infiltrates strongly suspected for Candida guilliermondii infection in a patient affected by T-cell Acute Lymphoblastic Leukemia (T-ALL) resistant to ...
Calogero Vetro   +7 more
doaj  

Deep and disseminated dermatophytosis in immunocompromised populations—A systematic review

open access: yesJournal of the European Academy of Dermatology and Venereology, EarlyView.
Dermatophyte infections of the dermis and subcutaneous tissue (i.e. deep dermatophytosis)—associated with secondary complications including pseudomycetoma and systemic dissemination—affect vulnerable populations with primary or acquired immunodeficiencies.
Aditya K. Gupta   +5 more
wiley   +1 more source

OX40/OX40L modulation: A target for regulating T cells in cutaneous inflammatory disorders

open access: yesJournal of the European Academy of Dermatology and Venereology, EarlyView.
OX40 and OX40L are a co‐stimulatory immune checkpoint pair. Modulation of this pair impacts multiple immune phenotypes and is an attractive target for immunotherapy in dermatological disorders. Trials are underway with the majority in atopic dermatitis and currently in phase 3 trials.
Aditya K. Gupta   +4 more
wiley   +1 more source

Erythrocyte ‘Feierzeit’ reaction: Novel filamentous and vesicular response to n‐butyl acetate

open access: yesJournal of Microscopy, EarlyView.
Abstract Human erythrocytes (red blood cells; RBCs) undergo spontaneous disassembly after several hours of exposure to n‐butyl acetate (nBA). Images of the morphological changes were captured in time‐lapse sequences using differential interference contrast (DIC) light microscopy.
Philip W. Kuchel
wiley   +1 more source

Severe and disseminated atypical mycobacteriosis of the skin under immunosuppression

open access: yes
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Veronika Zenderowski   +6 more
wiley   +1 more source

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