Results 141 to 150 of about 66,038 (239)

Endoplasmic reticulum stress and the unfolded protein response in lung diseases: molecular pathways and therapeutic interventions

The Journal of Pathology, Volume 269, Issue 3, Page 268-283, July 2026.
Abstract Endoplasmic reticulum stress (ERS) occurs when the protein‐folding capacity of the endoplasmic reticulum (ER) is overwhelmed, triggering the unfolded protein response (UPR) to restore homeostasis. However, severe or persistent ERS can shift the UPR toward pro‐inflammatory, apoptotic, and fibrotic signaling, thereby exacerbating tissue injury ...
Lanlan Song, Yichen Liu, Chen Xu, Yaochen Zhang, Kaiming Xu, Dan Yao, Xiaoying Huang   +6 more
wiley   +1 more source

Pulmonary Exacerbations and Treatment in PCD: A Narrative Review

Pediatric Pulmonology, Volume 61, Issue 7, July 2026.
ABSTRACT Primary ciliary dyskinesia (PCD) is a rare genetic disorder that causes chronic lung disease. Patients with PCD often experience pulmonary exacerbations with worsening symptoms and lung function decline. This review provides an overview of the existing knowledge regarding the PEx in PCD and reveals understudied topics that should be addressed ...
Pinelopi Anagnostopoulou, Stephanie Thee, Panayiotis Kouis, Panayiotis Yiallouros   +3 more
wiley   +1 more source

A Revised Model for Muscarine Biosynthesis Involving Lysine Trimethylation

Angewandte Chemie, Volume 138, Issue 24, 8 June 2026.
The fatal mushroom toxin l‐(+)‐muscarine is one of the most prominent natural products. We elucidated its biosynthetic origin in the sweating mushroom Collybia rivulosa based on incorporation of stable isotope‐labeled compounds and extensive mass spectrometric analyses.
Sebastian Dörner, Kai Rogge, Felix Trottmann, Christian Hertweck, Dirk Hoffmeister   +4 more
wiley   +2 more sources

<i>Scedosporium apiospermum</i> Infective Endocarditis With Brain Abscesses in a Lung Transplant Recipient: Review of the Literature and Evaluating the Use of Next-Generation Sequencing. [PDF]

Case Rep Infect Dis
Wong E, England J, Jagadeesan V.
europepmc   +1 more source

Associations Between Oral Health Related Outcomes and Electronic Cigarette Use in Young People: A Scoping Review

International Journal of Paediatric Dentistry, Volume 36, Issue 4, Page 577-584, July 2026.
ABSTRACT Background Vaping is prevalent among youth, but its effects on oral health remain poorly understood. Exposure to harmful chemicals and nicotine during this critical developmental period raises concerns for long‐term oral health impacts. Aim This scoping review synthesizes available evidence regarding oral health related outcomes of e‐cigarette
Jessica Tran, Hollie Bendotti, Moya Vandeleur   +2 more
wiley   +1 more source

Pulmonary aspergillosis complicated by recurrent pneumothorax in a person living with HIV: A case report. [PDF]

Radiol Case Rep
Sara K, Imane S, Brahim A, Mouna E.
europepmc   +1 more source

Insights Into the Susceptibility of Fungal Infection and STAT3 Genetic Mutations

Mycoses, Volume 69, Issue 7, July 2026.
ABSTRACT Signal transducer and activator of transcription 3 (STAT3) is a key transcription factor that regulates a spectrum of genes and signalling pathways critical for the antifungal immune response. Mutations in the STAT3 gene confer susceptibility to severe and recurrent fungal infections, predominantly via disruption of interleukin‐17 (IL‐17 ...
Fengming Li, Xiaodong Liu, Yuanyuan Li, Jie Wu, Ningning Dang, Jing Guo   +5 more
wiley   +1 more source

Alternatively activated monocyte-derived myeloid cells promote extracellular pathogen persistence in pulmonary fungal granulomas. [PDF]

J Exp Med
Zheng Y, Jean Pierre M, Ansaldo E, Dobson HE, Kamenyeva O, Onyishi CU, Douglas S, Febres Aldana C, Engin Zerk P, Sereti I, Betancourt JJ, Nielsen K, McCaffery E, Dang EV.   +13 more
europepmc   +1 more source

Empowering fungal infection research with single-cell RNA sequencing. [PDF]

Commun Biol
Toth R, Cabarrubias FR, Czimmerer Z, Vecsernyes-Nagy K, Gacser A.   +4 more
europepmc   +1 more source

A case of lung nodular aspergilloma mimicking tumor metastasis accompanied by pulmonary embolism in a gastric cancer patient in remission. [PDF]

SAGE Open Med Case Rep
Kaya AO, Kaya A, Gundogdu C.
europepmc   +1 more source