Results 191 to 200 of about 129,762 (268)

Combined pulmonary fibrosis and emphysema: a narrative review. [PDF]

Front Med (Lausanne)
Zeng W, Liang B, Ou X.
europepmc   +1 more source

Non‐invasive and efficient diabetic retinal mitochondrial repair nanoplatform based on engineered endothelial mitochondrial‐derived vesicles with dynamic integrated stress response modulation

Interdisciplinary Medicine, EarlyView.
Under hyperglycemic conditions, mitochondrial dysfunction in retinal endothelial cells triggers excessive reactive oxygen species/reactive nitrogen species production, barrier protein degradation, and endothelial barrier breakdown in diabetic retinopathy.
Siyu Gui, Jie Gao, Tianchang Tao, Peng Wang, Zhihao Huang, Yuyang She, Jiajie Li, Jingwan Su, Zhe Lu, Jianchao Qiao, Song Wang, Xiaodong Sun, Mohan Li   +12 more
wiley   +1 more source

Case Report: Pneumocystis jiroveci pneumonia: report of five children with the nephrotic syndrome and review of the literature. [PDF]

Front Pediatr
Han P, Yuan X, Li C, Zhang L, Cui J.
europepmc   +1 more source

Adipose‐derived small extracellular vesicles exacerbate microvascular dysfunction in heart failure with preserved ejection fraction via mmu‐miR‐582‐3p‐mediated Rap1b suppression

Interdisciplinary Medicine, EarlyView.
This study reveals that small extracellular vesicles (sEVs) from visceral fat compromise coronary microcirculation in a mouse model of heart failure with preserved ejection fraction (HFpEF). The SGLT2 inhibitor canagliflozin emerges as a therapeutic strategy, improving cardiac function and endothelial health.
Lu Chen, Qiuhan Wang, Mengjia Shen, Mingjue Li, Yingqi Zhu, Cankun Zheng, Siyuan Ma, Hairuo Lin, Xiaokang Fu, Rui Zhang, Jianping Bin, Yulin Liao, Qiancheng Wang   +12 more
wiley   +1 more source

Interstitial Lung Diseases in Israel: Large Variability in Close Geographic Proximity. [PDF]

Diagnostics (Basel)
Hershko T, Freund O, Schneer S, Segel MJ, Wand O, Bar-Shai A, Shitrit D, Levy L, Adir Y, Unterman A.   +9 more
europepmc   +1 more source

Lymph‐based liquid biopsy: Current progress and future potential

Interdisciplinary Medicine, EarlyView.
Recent evidence under the revised Starling principle indicates that lymph‐based liquid biopsies may offer superior diagnostic performance over blood‐based counterparts in certain clinical scenarios, such as early‐stage solid tumor detection. Currently, various biomarkers within the lymphatic system show significant diagnostic potential for a range of ...
Dongdong Liu, Leheng Cheng, Xiaolin Hu, Sergio Bernardini, Hong Zhang, Ling Zhu, Yang Luo   +6 more
wiley   +1 more source

Granulomatous Lymphocytic Interstitial Lung Disease as the Initial Manifestation of Common Variable Immunodeficiency in a Young Adult. [PDF]

Cureus
Almeida PS, Carvalho AM, Magalhães RG, Silveira-Rosa T, Silva JE.   +4 more
europepmc   +1 more source

Chronic Low‐Dose Unsymmetrical Dimethylhydrazine Exposure in Rats: Multiorgan Mechanisms and Biomarker Identification

Journal of Applied Toxicology, EarlyView.
ABSTRACT Unsymmetrical dimethylhydrazine (UDMH), a highly toxic rocket propellant with known multiorgan effects, requires urgent characterization of its chronic low‐dose toxicity. Using an integrated approach including exploratory transcriptomics (n = 3/group) and metabolomic (n = 4/group) approaches in male Sprague–Dawley rats exposed to high‐dose ...
Fuzhou Liu, Bing Liu, Keli Wang, Xiaoyu Wang, Zhen Sun, Xiaojuan Pan, Zengming Zhao   +6 more
wiley   +1 more source

ANCA-negative pauci-immune crescentic glomerulonephritis associated with nivolumab in lung cancer. [PDF]

CEN Case Rep
Furuyama R, Eriguchi M, Kamikawa M, Beppu Y, Tamaki H, Uemura T, Tasaki H, Nishimoto M, Kosugi T, Tanabe K, Matsui M, Samejima KI, Tsuruya K.   +12 more
europepmc   +1 more source